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Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis

Ebrahim Eskandari, Connie J. Eaves

J Cell Biol (2022) 221 (6): e202201159.

DOI: https://doi.org/10.1083/jcb.202201159

Published: 12 May 2022

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Journal Articles

Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering

Francesca Zappa, Nerea L. Muniozguren, Maxwell Z. Wilson, Michael S. Costello, Jose Carlos Ponce-Rojas, Diego Acosta-Alvear

J Cell Biol (2022) 221 (7): e202111100.

DOI: https://doi.org/10.1083/jcb.202111100

Published: 06 May 2022

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Includes: Supplementary data

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Secretory autophagy maintains proteostasis upon lysosome inhibition

Tina A. Solvik, Tan A. Nguyen, Yu-Hsiu Tony Lin, Timothy Marsh, Eric J. Huang, Arun P. Wiita, Jayanta Debnath, Andrew M. Leidal

J Cell Biol (2022) 221 (6): e202110151.

DOI: https://doi.org/10.1083/jcb.202110151

Published: 21 April 2022

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Includes: Supplementary data

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Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol (2022) 221 (6): e202201094.

DOI: https://doi.org/10.1083/jcb.202201094

Published: 21 April 2022

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Includes: Supplementary data

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Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

Ofer Guttman, Adrien Le Thomas, Scot Marsters, David A. Lawrence, Lauren Gutgesell, Iratxe Zuazo-Gaztelu, Jonathan M. Harnoss, Simone M. Haag, Aditya Murthy, Geraldine Strasser, Zora Modrusan, Thomas Wu, Ira Mellman, Avi Ashkenazi

J Cell Biol (2022) 221 (6): e202111068.

DOI: https://doi.org/10.1083/jcb.202111068

Published: 21 April 2022

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Includes: Supplementary data

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The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

J Cell Biol (2022) 221 (4): e202010065.

DOI: https://doi.org/10.1083/jcb.202010065

Published: 10 March 2022

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Includes: Supplementary data

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Ribbon boosts ribosomal protein gene expression to coordinate organ form and function

Rajprasad Loganathan, Daniel C. Levings, Ji Hoon Kim, Michael B. Wells, Hannah Chiu, Yifan Wu, Matthew Slattery, Deborah J. Andrew

J Cell Biol (2022) 221 (4): e202110073.

DOI: https://doi.org/10.1083/jcb.202110073

Published: 23 February 2022

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Includes: Supplementary data

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CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1

Xue Deng, Xing Sun, Wenkai Yue, Yongjia Duan, Rirong Hu, Kai Zhang, Jiangxia Ni, Jihong Cui, Qiangqiang Wang, Yelin Chen, Ang Li, Yanshan Fang

J Cell Biol (2021) 221 (1): e202103033.

DOI: https://doi.org/10.1083/jcb.202103033

Published: 02 November 2021

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Includes: Supplementary data

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Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion

Un Seng Chio, Yumeng Liu, SangYoon Chung, Woo Jun Shim, Sowmya Chandrasekar, Shimon Weiss, Shu-ou Shan

J Cell Biol (2021) 220 (11): e202103079.

DOI: https://doi.org/10.1083/jcb.202103079

Published: 06 October 2021

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Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine

Chen Chen, Yoshiaki Yamanaka, Koji Ueda, Peiying Li, Tamami Miyagi, Yuichiro Harada, Sayaka Tezuka, Satoshi Narumi, Masahiro Sugimoto, Masahiko Kuroda, Yuhei Hayamizu, Kohsuke Kanekura

J Cell Biol (2021) 220 (11): e202103160.

DOI: https://doi.org/10.1083/jcb.202103160

Published: 09 September 2021

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Includes: Supplementary data

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Translational regulation in the brain by TDP-43 phase separation

Ju Gao, Luwen Wang, Xiaojia Ren, Justin R. Dunn, Ariele Peters, Masaru Miyagi, Hisashi Fujioka, Fangli Zhao, Candice Askwith, Jingjing Liang, Xinglong Wang

J Cell Biol (2021) 220 (10): e202101019.

DOI: https://doi.org/10.1083/jcb.202101019

Published: 24 August 2021

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Includes: Supplementary data

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How the vacuole ESCRTs its own proteins to their final destination

W. Mike Henne

J Cell Biol (2021) 220 (8): e202105177.

DOI: https://doi.org/10.1083/jcb.202105177

Published: 19 July 2021

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Capture and delivery of tail-anchored proteins to the endoplasmic reticulum

Ákos Farkas, Katherine E. Bohnsack

J Cell Biol (2021) 220 (8): e202105004.

DOI: https://doi.org/10.1083/jcb.202105004

Published: 15 July 2021

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Journal Articles

Long-lived mitochondrial cristae proteins in mouse heart and brain

Ewa Bomba-Warczak, Seby L. Edassery, Timothy J. Hark, Jeffrey N. Savas

J Cell Biol (2021) 220 (9): e202005193.

DOI: https://doi.org/10.1083/jcb.202005193

Published: 14 July 2021

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Includes: Supplementary data

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Small-molecule modulators of INAVA cytosolic condensate and cell–cell junction assemblies

Denis Chang, Phi Luong, Qian Li, Jamie LeBarron, Michael Anderson, Lee Barrett, Wayne I. Lencer

J Cell Biol (2021) 220 (9): e202007177.

DOI: https://doi.org/10.1083/jcb.202007177

Published: 12 July 2021

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Includes: Supplementary data

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Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1

Kristina Väth, Carsten Mattes, John Reinhard, Roberto Covino, Heike Stumpf, Gerhard Hummer, Robert Ernst

J Cell Biol (2021) 220 (8): e202011078.

DOI: https://doi.org/10.1083/jcb.202011078

Published: 01 July 2021

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Includes: Supplementary data

Journal Articles

Go for the Golgi: Eating selectively with Calcoco1

Ai Yamamoto

J Cell Biol (2021) 220 (6): e202105005.

DOI: https://doi.org/10.1083/jcb.202105005

Published: 17 May 2021

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Journal Articles

A TRCky TA protein delivery service snubs the UPS

Alexander J. McQuown, Dvir Reif, Vladimir Denic

J Cell Biol (2021) 220 (5): e202103196.

DOI: https://doi.org/10.1083/jcb.202103196

Published: 20 April 2021

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Journal Articles

Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins

Jacob A. Culver, Malaiyalam Mariappan

J Cell Biol (2021) 220 (5): e202004086.

DOI: https://doi.org/10.1083/jcb.202004086

Published: 01 April 2021

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Journal Articles

The deubiquitylase USP9X controls ribosomal stalling

J Cell Biol (2021) 220 (3): e202004211.

DOI: https://doi.org/10.1083/jcb.202004211

Published: 28 January 2021

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Includes: Supplementary data

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Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis

Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering

Secretory autophagy maintains proteostasis upon lysosome inhibition

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

Ribbon boosts ribosomal protein gene expression to coordinate organ form and function

CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1

Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion

Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine

Translational regulation in the brain by TDP-43 phase separation

How the vacuole ESCRTs its own proteins to their final destination

Capture and delivery of tail-anchored proteins to the endoplasmic reticulum

Long-lived mitochondrial cristae proteins in mouse heart and brain

Small-molecule modulators of INAVA cytosolic condensate and cell–cell junction assemblies

Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1

Go for the Golgi: Eating selectively with Calcoco1

A TRCky TA protein delivery service snubs the UPS

Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins

The deubiquitylase USP9X controls ribosomal stalling

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