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Journal Articles

Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling

Jingya Xu, Xiaofei Li, Wei Chen, Ziyin Zhang, Yanping Zhou, Yahui Gou, Cheng-an Lv, Lu Jin, Xinyuan Qiu, Shengshan Ma, Qing-Qian Wu, Tongyu Liu, Lin Mi, Zhuoying Yang, Ting Yu, Xiaowen Pan, Yu Feng, Pengfei Shan, Zhuo-Xian Meng
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (9): e20221123.
DOI: https://doi.org/10.1084/jem.20221123
Published: 07 June 2023
View article titled, Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling
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Includes: Supplementary data
Journal Articles

Inborn errors of human B cell development, differentiation, and function

Stuart G. Tangye, Tina Nguyen, Elissa K. Deenick, Vanessa L. Bryant, Cindy S. Ma
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (7): e20221105.
DOI: https://doi.org/10.1084/jem.20221105
Published: 05 June 2023
View article titled, Inborn errors of human B cell development, differentiation, and function
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Journal Articles

Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity

Kunihiko Moriya, Tomohiro Nakano, Yoshitaka Honda, Miyuki Tsumura, Masato Ogishi, Motoshi Sonoda, Masahiko Nishitani-Isa, Takashi Uchida, Mohamed Hbibi, Yoko Mizoguchi, Masataka Ishimura, Kazushi Izawa, Takaki Asano, Fumihiko Kakuta, Daiki Abukawa, Darawan Rinchai, Peng Zhang, Naotomo Kambe, Aziz Bousfiha, Takahiro Yasumi, Bertrand Boisson, Anne Puel, Jean-Laurent Casanova, Ryuta Nishikomori, Shouichi Ohga, Satoshi Okada, Yoji Sasahara, Shigeo Kure
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (9): e20212276.
DOI: https://doi.org/10.1084/jem.20212276
Published: 05 June 2023
View article titled, Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity
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Includes: Supplementary data
Journal Articles

Type 2 inflammation and biological therapies in asthma: Targeted medicine taking flight

Imran Howell, Aleksandra Howell, Ian D. Pavord
Journal: Journal of Experimental Medicine
Series: Th2 responses
J Exp Med (2023) 220 (7): e20221212.
DOI: https://doi.org/10.1084/jem.20221212
Published: 02 June 2023
View article titled, Type 2 inflammation and biological therapies in asthma: Targeted medicine taking flight
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Journal Articles

Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis

In Special Collection:
Journal-Based CME Activities with Journal of Experimental Medicine (JEM)
Tae Sung Kim, Lakmali M. Silva, Vasileios Ionas Theofilou, Teresa Greenwell-Wild, Lu Li, Drake Winslow Williams, Tomoko Ikeuchi, Laurie Brenchley, NIDCD/NIDCR Genomics and Computational Biology Core, Thomas H. Bugge, Patricia I. Diaz, Mariana J. Kaplan, Carmelo Carmona-Rivera, Niki M. Moutsopoulos
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (9): e20221751.
DOI: https://doi.org/10.1084/jem.20221751
Published: 01 June 2023
View article titled, Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis
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Includes: Supplementary data
Journal Articles

Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis

Hannah A. Pizzato, Yahui Wang, Michael J. Wolfgang, Brian N. Finck, Gary J. Patti, Deepta Bhattacharya
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (9): e20221373.
DOI: https://doi.org/10.1084/jem.20221373
Published: 30 May 2023
View article titled, Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis
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Journal Articles

Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells

Ainsley Lockhart, Aubrey Reed, Tiago Rezende de Castro, Calvin Herman, Maria Cecilia Campos Canesso, Daniel Mucida
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221816.
DOI: https://doi.org/10.1084/jem.20221816
Published: 16 May 2023
View article titled, Dietary protein shapes the profile and repertoire of intestinal CD4<sup>+</sup> T cells
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Includes: Supplementary data
Journal Articles

Guardians of the oral barriers

Marcus Buggert
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (7): e20230550.
DOI: https://doi.org/10.1084/jem.20230550
Published: 15 May 2023
View article titled, Guardians of the oral barriers
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Journal Articles

Identification of an anergic BND cell–derived activated B cell population (BND2) in young-onset type 1 diabetes patients

In Special Collection:
B cells, Infectious Diseases, and Autoimmunity
Zachary C. Stensland, Christopher A. Magera, Hali Broncucia, Brittany D. Gomez, Nasha M. Rios-Guzman, Kristen L. Wells, Catherine A. Nicholas, Marynette Rihanek, Maya J. Hunter, Kevin P. Toole, Peter A. Gottlieb, Mia J. Smith
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221604.
DOI: https://doi.org/10.1084/jem.20221604
Published: 15 May 2023
View article titled, Identification of an anergic B<sub>ND</sub> cell–derived activated B cell population (B<sub>ND</sub>2) in young-onset type 1 diabetes patients
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Includes: Supplementary data
Journal Articles

Obesity alters monocyte developmental trajectories to enhance metastasis

Sheri A.C. McDowell, Simon Milette, Samuel Doré, Miranda W. Yu, Mark Sorin, Liam Wilson, Lysanne Desharnais, Alyssa Cristea, Ozgun Varol, Aline Atallah, Anikka Swaby, Valérie Breton, Azadeh Arabzadeh, Sarah Petrecca, Hamza Loucif, Aanya Bhagrath, Meghan De Meo, Katherine D. Lach, Marianne S.M. Issac, Benoit Fiset, Roni F. Rayes, Judith N. Mandl, Jörg H. Fritz, Pierre O. Fiset, Peter R. Holt, Andrew J. Dannenberg, Jonathan D. Spicer, Logan A. Walsh, Daniela F. Quail
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20220509.
DOI: https://doi.org/10.1084/jem.20220509
Published: 11 May 2023
View article titled, Obesity alters monocyte developmental trajectories to enhance metastasis
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Includes: Supplementary data
Journal Articles

Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice

Wanlin Cui, Yuji Nagano, Satoru Morita, Takeshi Tanoue, Hidehiro Yamane, Keiko Ishikawa, Toshiro Sato, Masato Kubo, Shohei Hori, Tadatsugu Taniguchi, Masanori Hatakeyama, Koji Atarashi, Kenya Honda
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221773.
DOI: https://doi.org/10.1084/jem.20221773
Published: 10 May 2023
View article titled, Diet-mediated constitutive induction of novel IL-4<sup>+</sup> ILC2 cells maintains intestinal homeostasis in mice
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Journal Articles

T helper 2 cells in asthma

James A. Harker, Clare M. Lloyd
Journal: Journal of Experimental Medicine
Series: Th2 responses
J Exp Med (2023) 220 (6): e20221094.
DOI: https://doi.org/10.1084/jem.20221094
Published: 10 May 2023
View article titled, T helper 2 cells in asthma
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Journal Articles

TB granuloma: CD30 co-stimulation for CD4+ T cell co-operation

Abigail R. Gress, Tyler D. Bold
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20230547.
DOI: https://doi.org/10.1084/jem.20230547
Published: 09 May 2023
View article titled, TB granuloma: CD30 co-stimulation for CD4<sup>+</sup> T cell co-operation
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Journal Articles

The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage

You-Sheng Lin, Yung-Chi Chang, Tai-Ling Chao, Ya-Min Tsai, Shu-Jhen Jhuang, Yu-Hsin Ho, Ting-Yu Lai, Yi-Ling Liu, Chiung-Ya Chen, Ching-Yen Tsai, Yi-Ping Hsueh, Sui-Yuan Chang, Tsung-Hsien Chuang, Chih-Yuan Lee, Li-Chung Hsu
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20220727.
DOI: https://doi.org/10.1084/jem.20220727
Published: 09 May 2023
View article titled, The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage
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Includes: Supplementary data
Journal Articles

OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

Ning Yang, Yi Wang, Shuaitong Liu, Shanza Baseer Tariq, Joseph M. Luna, Gregory Mazo, Adrian Tan, Tuo Zhang, Jiahu Wang, Wei Yan, John Choi, Anthony Rossi, Jenny Zhaoying Xiang, Charles M. Rice, Taha Merghoub, Jedd D. Wolchok, Liang Deng
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221166.
DOI: https://doi.org/10.1084/jem.20221166
Published: 05 May 2023
View article titled, OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs
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Includes: Supplementary data
Journal Articles

Intracellular trafficking of HLA-E and its regulation

In Special Collection:
B cells, Infectious Diseases, and Autoimmunity
Wanlin He, Ester Gea-Mallorquí, Huw Colin-York, Marco Fritzsche, Geraldine M. Gillespie, Simon Brackenridge, Persephone Borrow, Andrew J. McMichael
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221941.
DOI: https://doi.org/10.1084/jem.20221941
Published: 04 May 2023
View article titled, Intracellular trafficking of HLA-E and its regulation
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Includes: Supplementary data
Journal Articles

SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19

In Special Collection:
Journal-Based CME Activities with Journal of Experimental Medicine (JEM)
Ksenia Rybkina, Joseph N. Bell, Marissa C. Bradley, Teddy Wohlbold, Marika Scafuro, Wenzhao Meng, Rebecca C. Korenberg, Julia Davis-Porada, Brett R. Anderson, Rachel J. Weller, Joshua D. Milner, Anne Moscona, Matteo Porotto, Eline T. Luning Prak, Kalpana Pethe, Thomas J. Connors, Donna L. Farber
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20221518.
DOI: https://doi.org/10.1084/jem.20221518
Published: 03 May 2023
View article titled, SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19
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Includes: Supplementary data
Journal Articles

Breaking bad

Mohini Bhattacharya, Alexander R. Horswill
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (6): e20230421.
DOI: https://doi.org/10.1084/jem.20230421
Published: 02 May 2023
View article titled, Breaking bad
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Journal Articles

Ruth Scherz-Shouval: Together we can ask big questions

Lucie Van Emmenis
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (6): e20230600.
DOI: https://doi.org/10.1084/jem.20230600
Published: 28 April 2023
View article titled, Ruth Scherz-Shouval: Together we can ask big questions
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Journal Articles

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

Kristina Zec, Barbora Schonfeldova, Zhichao Ai, Erinke Van Grinsven, Gabriela Pirgova, Hayley L. Eames, Dorothée L. Berthold, Moustafa Attar, Ewoud B. Compeer, Tal I. Arnon, Irina A. Udalova
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (8): e20220595.
DOI: https://doi.org/10.1084/jem.20220595
Published: 28 April 2023
View article titled, Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation
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Includes: Supplementary data