Flagellates of Naegleria gruberi have an interconnected flagellar apparatus consisting of nucleus, rhizoplast and accessory filaments, basal bodies, and flagella. The structures of these components have been found to be similar to those in other flagellates. The development of methods for obtaining the relatively synchronous transformation of populations of Naegleria amebae into flagellates has permitted a study of the development of the flagellar apparatus. No indications of rhizoplast, basal body, or flagellum structures could be detected in amebae. A basal body appears and assumes a position at the cell surface with its filaments perpendicular to the cell membrane. Axoneme filaments extend from the basal body filaments into a progressive evagination of the cell membrane which becomes the flagellum sheath. Continued elongation of the axoneme filaments leads to differentiation of a fully formed flagellum with a typical "9 + 2" organization, within 10 min after the appearance of basal bodies.
Article|
October 01 1966
DEVELOPMENT OF THE FLAGELLAR APPARATUS OF NAEGLERIA
Allan D. Dingle,
Allan D. Dingle
From the Department of Biology, Brandeis University, Waltham, Massachusetts.
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Chandler Fulton
Chandler Fulton
From the Department of Biology, Brandeis University, Waltham, Massachusetts.
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Allan D. Dingle
From the Department of Biology, Brandeis University, Waltham, Massachusetts.
Chandler Fulton
From the Department of Biology, Brandeis University, Waltham, Massachusetts.
Dr. Dingle's present address is the Research Unit in Biochemistry, Biophysics, and Molecular Biology, McMaster University, Hamilton, Ontario, Canada
Received:
February 16 1966
Online ISSN: 1540-8140
Print ISSN: 0021-9525
Copyright © 1966 by The Rockefeller University Press
1966
J Cell Biol (1966) 31 (1): 43–54.
Article history
Received:
February 16 1966
Citation
Allan D. Dingle, Chandler Fulton; DEVELOPMENT OF THE FLAGELLAR APPARATUS OF NAEGLERIA . J Cell Biol 1 October 1966; 31 (1): 43–54. doi: https://doi.org/10.1083/jcb.31.1.43
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