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18 May 2009
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Cover Image
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On the cover
A 3D reconstruction of the different membrane compartments of a budding yeast cell. Klemm et al. devise new methods to purify secretory vesicles (red) and Golgi/endosomes (yellow), and analyze their lipid composition, suggesting a mechanism for both protein and lipid sorting at the trans-Golgi network.
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ISSN 0021-9525
EISSN 1540-8140
In this Issue
In This Issue
In Focus
Lipid rafts inflate at the trans-Golgi
A new method to characterize the lipid content of vesicles suggests how cells sort secretory cargo.
People & Ideas
David Sherwood: Invasive procedures
Sherwood uses a unique in vivo model to study how cells invade through extracellular barriers.
Editorial
Review
Report
Heterochromatin protein 1 is recruited to various types of DNA damage
Martijn S. Luijsterburg,Christoffel Dinant,Hannes Lans,Jan Stap,Elzbieta Wiernasz,Saskia Lagerwerf,Daniël O. Warmerdam,Michael Lindh,Maartje C. Brink,Jurek W. Dobrucki,Jacob A. Aten,Maria I. Fousteri,Gert Jansen,Nico P. Dantuma,Wim Vermeulen,Leon H.F. Mullenders,Adriaan B. Houtsmuller,Pernette J. Verschure,Roel van Driel