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Albert Reynolds (1956–2022): The father of p120

Gregg Wildenberg, Deborah J. Mariner, Panos Z. Anastasiadis, Micheal A. Davis, Renee Ireton, Huapeng Yu, Andrew L. Smith, Sarah Kurley, Juliet M. Daniel, Agnes Roczniak-Ferguson, Xiaobo Xia, Meredith Brown, Manish Tripathi, Molly Seale, Robert Carnahan, Whitney Smalley-Freed, Michael Dohn

J Cell Biol (2023) 222 (2): e202211100.

DOI: https://doi.org/10.1083/jcb.202211100

Published: 27 January 2023

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ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia

Gabriel Kreider-Letterman, Abel Castillo, Eike K. Mahlandt, Joachim Goedhart, Agustin Rabino, Silvia Goicoechea, Rafael Garcia-Mata

J Cell Biol (2022) 222 (2): e202207020.

DOI: https://doi.org/10.1083/jcb.202207020

Published: 26 December 2022

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Includes: Supplementary data

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α-Tubulin detyrosination links the suppression of MCAK activity with taxol cytotoxicity

Danilo Lopes, Alexandre L. Seabra, Bernardo Orr, Helder Maiato

J Cell Biol (2022) 222 (2): e202205092.

DOI: https://doi.org/10.1083/jcb.202205092

Published: 02 December 2022

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ATM inhibition drives metabolic adaptation via induction of macropinocytosis

Zhentai Huang, Chi-Wei Chen, Raquel Buj, Naveen Kumar Tangudu, Richard S. Fang, Kelly E. Leon, Erika S. Dahl, Erika L. Varner, Eliana von Krusenstiern, Aidan R. Cole, Nathaniel W. Snyder, Katherine M. Aird

J Cell Biol (2022) 222 (1): e202007026.

DOI: https://doi.org/10.1083/jcb.202007026

Published: 18 November 2022

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Aberrant phosphorylation inactivates Numb in breast cancer causing expansion of the stem cell pool

Maria Grazia Filippone, Stefano Freddi, Silvia Zecchini, Silvia Restelli, Ivan Nicola Colaluca, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Pier Paolo Di Fiore

J Cell Biol (2022) 221 (12): e202112001.

DOI: https://doi.org/10.1083/jcb.202112001

Published: 06 October 2022

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Includes: Supplementary data

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In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish

Dagan Segal, Hanieh Mazloom-Farsibaf, Bo-Jui Chang, Philippe Roudot, Divya Rajendran, Stephan Daetwyler, Reto Fiolka, Mikako Warren, James F. Amatruda, Gaudenz Danuser

J Cell Biol (2022) 221 (11): e202109100.

DOI: https://doi.org/10.1083/jcb.202109100

Published: 26 September 2022

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Includes: Supplementary data

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Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells

Rebecca Harris, Ming Yang, Christina Schmidt, Chloe Royet, Sarbjit Singh, Amarnath Natarajan, May Morris, Christian Frezza, Heike Laman

J Cell Biol (2022) 221 (7): e202203095.

DOI: https://doi.org/10.1083/jcb.202203095

Published: 07 June 2022

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DPYSL2 interacts with JAK1 to mediate breast cancer cell migration

Areej Abu Rmaileh, Balakrishnan Solaimuthu, Anees Khatib, Shirel Lavi, Mayur Tanna, Arata Hayashi, Michal Ben Yosef, Michal Lichtenstein, Nir Pillar, Yoav D. Shaul

J Cell Biol (2022) 221 (7): e202106078.

DOI: https://doi.org/10.1083/jcb.202106078

Published: 16 May 2022

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Includes: Supplementary data

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Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis

Ebrahim Eskandari, Connie J. Eaves

J Cell Biol (2022) 221 (6): e202201159.

DOI: https://doi.org/10.1083/jcb.202201159

Published: 12 May 2022

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Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes

Lisa Donker, Susana A. Godinho

J Cell Biol (2022) 221 (6): e202204114.

DOI: https://doi.org/10.1083/jcb.202204114

Published: 10 May 2022

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Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

In Special Collection:

Chromatin Biology 2022 , The Year in Cell Biology: 2022

Nuria Ferrandiz, Laura Downie, Georgina P. Starling, Stephen J. Royle

J Cell Biol (2022) 221 (6): e202203021.

DOI: https://doi.org/10.1083/jcb.202203021

Published: 29 April 2022

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Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

Ofer Guttman, Adrien Le Thomas, Scot Marsters, David A. Lawrence, Lauren Gutgesell, Iratxe Zuazo-Gaztelu, Jonathan M. Harnoss, Simone M. Haag, Aditya Murthy, Geraldine Strasser, Zora Modrusan, Thomas Wu, Ira Mellman, Avi Ashkenazi

J Cell Biol (2022) 221 (6): e202111068.

DOI: https://doi.org/10.1083/jcb.202111068

Published: 21 April 2022

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Includes: Supplementary data

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Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol (2022) 221 (6): e202201094.

DOI: https://doi.org/10.1083/jcb.202201094

Published: 21 April 2022

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An unexpected role for PD-L1 in front–rear polarization and directional migration

Miguel Sánchez-Álvarez, Miguel A. del Pozo

J Cell Biol (2022) 221 (5): e202203137.

DOI: https://doi.org/10.1083/jcb.202203137

Published: 13 April 2022

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PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics

Mengdie Wang, Choua Xiong, Arthur M. Mercurio

J Cell Biol (2022) 221 (5): e202108083.

DOI: https://doi.org/10.1083/jcb.202108083

Published: 28 March 2022

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Non-canonical ubiquitylation makes its mark on Rap2 and cell motility

Patrick T. Caswell

J Cell Biol (2022) 221 (4): e202203029.

DOI: https://doi.org/10.1083/jcb.202203029

Published: 25 March 2022

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A JAM-A–tetraspanin–αvβ5 integrin complex regulates contact inhibition of locomotion

J Cell Biol (2022) 221 (4): e202105147.

DOI: https://doi.org/10.1083/jcb.202105147

Published: 16 March 2022

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Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling

Rebecca Cabral-Dias, Stefanie Lucarelli, Karolina Zak, Sadia Rahmani, Gurjeet Judge, John Abousawan, Laura F. DiGiovanni, Dafne Vural, Karen E. Anderson, Michael G. Sugiyama, Gizem Genc, Wanjin Hong, Roberto J. Botelho, Gregory D. Fairn, Peter K. Kim, Costin N. Antonescu

J Cell Biol (2022) 221 (4): e201808181.

DOI: https://doi.org/10.1083/jcb.201808181

Published: 03 March 2022

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Includes: Supplementary data

Journal Articles

Active RB causes visible changes in nuclear organization

In Special Collection:

Chromatin Biology 2022

Badri Krishnan, Takaaki Yasuhara, Purva Rumde, Marcello Stanzione, Chenyue Lu, Hanjun Lee, Michael S. Lawrence, Lee Zou, Linda T. Nieman, Ioannis Sanidas, Nicholas J. Dyson

J Cell Biol (2022) 221 (3): e202102144.

DOI: https://doi.org/10.1083/jcb.202102144

Published: 12 January 2022

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Journal Articles

Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression

In Special Collection:

Chromatin Biology 2022

Rebeca San Martin, Priyojit Das, Renata Dos Reis Marques, Yang Xu, Justin M. Roberts, Jacob T. Sanders, Rosela Golloshi, Rachel Patton McCord

J Cell Biol (2021) 221 (2): e202104108.

DOI: https://doi.org/10.1083/jcb.202104108

Published: 10 December 2021

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Includes: Supplementary data

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Albert Reynolds (1956–2022): The father of p120

ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia

α-Tubulin detyrosination links the suppression of MCAK activity with taxol cytotoxicity

ATM inhibition drives metabolic adaptation via induction of macropinocytosis

Aberrant phosphorylation inactivates Numb in breast cancer causing expansion of the stem cell pool

In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish

Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells

DPYSL2 interacts with JAK1 to mediate breast cancer cell migration

Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis

Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes

Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

Tumor suppressor BAP1 nuclear import is governed by transportin-1

An unexpected role for PD-L1 in front–rear polarization and directional migration

PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics

Non-canonical ubiquitylation makes its mark on Rap2 and cell motility

A JAM-A–tetraspanin–αvβ5 integrin complex regulates contact inhibition of locomotion

Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling

Active RB causes visible changes in nuclear organization

Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression

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