Purified antibodies against three different antigens and haptens (ovalbumin, dinitrophenol, and Type II pneumococcal polysaccharide) were prepared from specific precipitates from the antisera of several rabbits. The reactions of these preparations with antisera against the allotypic specificities carried by each of the animals forming the antibodies were used to compare the relative concentrations of molecules bearing each specificity in the different solutions of antibodies from each rabbit. These relative concentrations appeared to vary greatly from one preparation to another, although all the allotypic specificities carried by each animal were found in all the preparations of antibodies from that animal. The interpretation of these results is discussed.
Article|
October 01 1963
STUDIES ON THE RELATIONSHIP OF ALLOTYPIC SPECIFICITIES TO ANTIBODY SPECIFICITIES IN THE RABBIT
Ronald F. Rieder,
Ronald F. Rieder
From the Service d'Immunochimie Analytique, Institut Pasteur, Paris, France
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Jacques Oudin
Jacques Oudin
From the Service d'Immunochimie Analytique, Institut Pasteur, Paris, France
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Ronald F. Rieder
From the Service d'Immunochimie Analytique, Institut Pasteur, Paris, France
Jacques Oudin
From the Service d'Immunochimie Analytique, Institut Pasteur, Paris, France
Received:
June 05 1963
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright © 1963, by The Rockefeller Institute
1963
J Exp Med (1963) 118 (4): 627–633.
Article history
Received:
June 05 1963
Citation
Ronald F. Rieder, Jacques Oudin; STUDIES ON THE RELATIONSHIP OF ALLOTYPIC SPECIFICITIES TO ANTIBODY SPECIFICITIES IN THE RABBIT . J Exp Med 1 October 1963; 118 (4): 627–633. doi: https://doi.org/10.1084/jem.118.4.627
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