An acute frequently rapidly fatal respiratory illness occurring as an epidemic disease in Argentine swine has been shown to have a bacterium of the genus Hemophilus as its causative agent. This organism, for which the name Hemophilus pleuropneumoniae is suggested, causes a singular, fulminating pleuropneumonia in experimental swine. The very marked effectiveness of H. pleuropneumoniae as a respiratory pathogen contrasts strikingly with the relatively mild pathogenicity of the well known swine Hemophilus, H. influenzae suis, which, in concert with a virus, causes a less highly fatal respiratory ailment, swine influenza. Porcine contagious pleuropneumonia (PCP) is contagious under experimental conditions. In the pathogenesis of the disease, histopathological studies of early cases suggest that the lymphatics of the lung and pleura may be primarily involved and that the pneumonia and pleuritis then proceed from these initial sites of reaction.
Article|
March 01 1964
PORCINE CONTAGIOUS PLEUROPNEUMONIA : I. EXPERIMENTAL TRANSMISSION, ETIOLOGY, AND PATHOLOGY
Richard E. Shope
Richard E. Shope
From The Rockefeller Institute
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Richard E. Shope
From The Rockefeller Institute
Received:
November 03 1963
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright © 1964, by The Rockefeller Institute
1964
J Exp Med (1964) 119 (3): 357–368.
Article history
Received:
November 03 1963
Citation
Richard E. Shope; PORCINE CONTAGIOUS PLEUROPNEUMONIA : I. EXPERIMENTAL TRANSMISSION, ETIOLOGY, AND PATHOLOGY . J Exp Med 1 March 1964; 119 (3): 357–368. doi: https://doi.org/10.1084/jem.119.3.357
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