A series of pulse-doses of 7, 8, 12-trimethylbenz(a)anthracene-induced leukemia rapidly and consistently in very high yield in rats of Long-Evans (L-E) strain. The predominant type was a diffuse hepatic leukemia of erythroblastic stem cells.
Progressive hypothermia and a decline in pituitary function are newly recognized signs of advanced leukemia in rat.
Copyright © 1970 by The Rockefeller University Press
1970
