The helper function of carrier-primed T cells was found to be radiosensitive in vivo. The results could not be attributed to interference with the spleen-seeking properties of the irradiated cells. It is suggested that T cell division is essential for the induction of 7S antibody responses in vivo.
CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE : VIII. RADIOSENSITIVITY OF THYMUS-DERIVED LYMPHOCYTES
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R. E. Anderson, J. Sprent, J. F. A. P. Miller; CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE : VIII. RADIOSENSITIVITY OF THYMUS-DERIVED LYMPHOCYTES . J Exp Med 1 March 1972; 135 (3): 711–717. doi: https://doi.org/10.1084/jem.135.3.711
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