IDIOTYPIC DETERMINANTS OF IMMUNOGLOBULIN M DETECTED ON THE SURFACE OF HUMAN LYMPHOCYTES BY CYTOTOXICITY ASSAYS

Wernet , P.; Feizi , T.; Kunkel , H. G.

doi:10.1084/jem.136.3.650

P. Wernet,

P. Wernet

From The Rockefeller University, New York 10021

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T. Feizi,

T. Feizi

From The Rockefeller University, New York 10021

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H. G. Kunkel

From The Rockefeller University, New York 10021

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P. Wernet

From The Rockefeller University, New York 10021

T. Feizi

From The Rockefeller University, New York 10021

H. G. Kunkel

From The Rockefeller University, New York 10021

Received: June 23 1972

Online Issn: 1540-9538

Print Issn: 0022-1007

1972

The complement-mediated cytotoxicity assay has been used to demonstrate surface immunoglobulin determinants on human peripheral blood lymphocytes. In two individuals with monoclonal serum IgM components, idiotypic antisera demonstrated similar components on a significant proportion of the peripheral blood lymphocytes.

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1972

IDIOTYPIC DETERMINANTS OF IMMUNOGLOBULIN M DETECTED ON THE SURFACE OF HUMAN LYMPHOCYTES BY CYTOTOXICITY ASSAYS

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IDIOTYPIC DETERMINANTS OF IMMUNOGLOBULIN M DETECTED ON THE SURFACE OF HUMAN LYMPHOCYTES BY CYTOTOXICITY ASSAYS

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