Polymorphonuclear leukocyte chemotaxis has been elicited by oxidized arachidonic acid and other oxidized polyenoic lipids in the Boyden micropore filter assay system. This chemotactic activity was observed in the absence of serum and chemotactic proteins. The esterfied arachidonic acid present in plasma membranes may be a precursor of chemotactic messages as well as prostaglandins in vivo.
Article| June 01 1975
Polymorphonulcear leukocyte chemotaxis toward oxidized lipid components of cell membranes.
S R Turner
J A Campbell
W S Lynn
Online ISSN: 1540-9538
Print ISSN: 0022-1007
J Exp Med (1975) 141 (6): 1437–1441.
S R Turner, J A Campbell, W S Lynn; Polymorphonulcear leukocyte chemotaxis toward oxidized lipid components of cell membranes.. J Exp Med 1 June 1975; 141 (6): 1437–1441. doi: https://doi.org/10.1084/jem.141.6.1437
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