Neonatally initiated injection of anti-mu antiserum in mice has been shown to suppress the formation of reaginic antibodies in response to infection with the intestinal nematode, Nippostrongylus brasiliensis. This observation supports the hypothesis that IgE-producing cells arise from IgM-bearing precursors.
Article| July 01 1976
Suppression of reaginic antibody (IgE) formation in mice by treatment with anti-mu antiserum.
D D Manning
J K Manning
N D Reed
Online ISSN: 1540-9538
Print ISSN: 0022-1007
J Exp Med (1976) 144 (1): 288–292.
D D Manning, J K Manning, N D Reed; Suppression of reaginic antibody (IgE) formation in mice by treatment with anti-mu antiserum.. J Exp Med 1 July 1976; 144 (1): 288–292. doi: https://doi.org/10.1084/jem.144.1.288
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