AH antigen, initially defined by an antibody present in a melanoma patient, is a cell surface antigen found on approximately 65% of melanoma cell lines. Absorption analysis indicates that AH is a differentiation antigen marking normal and malignant cells of neuroectodermal origin. The AH determinant has been found to be related to GD2 ganglioside.
Human melanoma antigen AH is an autoantigenic ganglioside related to GD2.
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T Watanabe, C S Pukel, H Takeyama, K O Lloyd, H Shiku, L T Li, L R Travassos, H F Oettgen, L J Old; Human melanoma antigen AH is an autoantigenic ganglioside related to GD2.. J Exp Med 1 December 1982; 156 (6): 1884–1889. doi: https://doi.org/10.1084/jem.156.6.1884
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