Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2.
Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.
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W C Greene, R J Robb, P B Svetlik, C M Rusk, J M Depper, W J Leonard; Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.. J Exp Med 1 July 1985; 162 (1): 363–368. doi: https://doi.org/10.1084/jem.162.1.363
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