The method of study has an objective somewhat different from, and lacking the precision of, the ratio of Addis and the urea clearance of Van Slyke. It serves, however, to demonstrate that although for a month after unilateral nephrectomy the remaining kidney shows diminished capacity to hold blood urea within the normal range, nevertheless after 4 months this function is maintained in essentially the same degree as if both kidneys were present. This does not imply that all activities of the kidney remaining after unilateral nephrectomy are potentially augmented, but the data offered justify the conclusion that as the remaining kidney undergoes enlargement its functional capacity increases and the process represents a genuine hypertrophy in the critical sense.
Article|
January 01 1932
UREA TOLERANCE AFTER UNILATERAL NEPHRECTOMY IN RABBITS
Howard T. Karsner,
Howard T. Karsner
From the Institute of Pathology, Western Reserve University, Cleveland
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Ruben Straus,
Ruben Straus
From the Institute of Pathology, Western Reserve University, Cleveland
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Robert A. Moore,
Robert A. Moore
From the Institute of Pathology, Western Reserve University, Cleveland
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Ramon F. Hanzal
Ramon F. Hanzal
From the Institute of Pathology, Western Reserve University, Cleveland
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Howard T. Karsner
From the Institute of Pathology, Western Reserve University, Cleveland
Ruben Straus
From the Institute of Pathology, Western Reserve University, Cleveland
Robert A. Moore
From the Institute of Pathology, Western Reserve University, Cleveland
Ramon F. Hanzal
From the Institute of Pathology, Western Reserve University, Cleveland
Received:
October 04 1931
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright, 1932, by The Rockefeller Institute for Medical Research New York
1932
J Exp Med (1932) 55 (1): 27–30.
Article history
Received:
October 04 1931
Citation
Howard T. Karsner, Ruben Straus, Robert A. Moore, Ramon F. Hanzal; UREA TOLERANCE AFTER UNILATERAL NEPHRECTOMY IN RABBITS . J Exp Med 1 January 1932; 55 (1): 27–30. doi: https://doi.org/10.1084/jem.55.1.27
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