Of the two etiological components of swine influenza, only the filtrable virus possessed immunizing properties. H. influenzae suis, while essential to the production of the disease, played only a secondary and contributory rôle and, alone, conferred no immunity. Serum of swine convalescent from the filtrate disease neutralized the swine influenza etiological complex of organism and virus. Intramuscularly administered swine influenza virus was incapable of inducing illness but did render hogs immune to swine influenza. It is suggested that a specific relationship, as regards infectivity, exists between the swine influenza virus and the tissues of the respiratory tract.
Article| October 01 1932
STUDIES ON IMMUNITY TO SWINE INFLUENZA
Richard E. Shope
From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
Received: June 19 1932
Online Issn: 1540-9538
Print Issn: 0022-1007
Copyright, 1932, by The Rockefeller Institute for Medical Research New York
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Richard E. Shope; STUDIES ON IMMUNITY TO SWINE INFLUENZA . J Exp Med 1 October 1932; 56 (4): 575–585. doi: https://doi.org/10.1084/jem.56.4.575
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