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1 May 1996
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In this Issue
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.
Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin.
Induction of passive Heymann nephritis with antibodies specific for a synthetic peptide derived from the receptor-associated protein.
Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways.
T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.
Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules.
The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells.
An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes.
CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.
A Oxenius,K A Campbell,C R Maliszewski,T Kishimoto,H Kikutani,H Hengartner,R M Zinkernagel,M F Bachmann
Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death.
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis.
S Nicholson,M da G Bonecini-Almeida,J R Lapa e Silva,C Nathan,Q W Xie,R Mumford,J R Weidner,J Calaycay,J Geng,N Boechat,C Linhares,W Rom,J L Ho
Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation.
The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.
Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice.
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.
Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2.
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling.
Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin.
M Uguccioni,P Loetscher,U Forssmann,B Dewald,H Li,S H Lima,Y Li,B Kreider,G Garotta,M Thelen,M Baggiolini
Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells.
RANTES and macrophage inflammatory protein 1 alpha selectively enhance immunoglobulin (IgE) and IgG4 production by human B cells.
Suboptimal activation of melanoma infiltrating lymphocytes (TIL) due to low avidity of TCR/MHC-tumor peptide interactions.
Th2 responsesT helper 2 cells in asthma