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Journal Articles

JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia

In Special Collection:
Hematologic malignancies 2019
Marc R. Mansour, Shuning He, Zhaodong Li, Riadh Lobbardi, Brian J. Abraham, Clemens Hug, Sunniyat Rahman, Theresa E. Leon, You-Yi Kuang, Mark W. Zimmerman, Traci Blonquist, Evisa Gjini, Alejandro Gutierrez, Qin Tang, Laura Garcia-Perez, Karin Pike-Overzet, Lars Anders, Alla Berezovskaya, Yi Zhou, Leonard I. Zon, Donna Neuberg, Adele K. Fielding, Frank J.T. Staal, David M. Langenau, Takaomi Sanda, Richard A. Young, A. Thomas Look
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (7): 1929–1945.
DOI: https://doi.org/10.1084/jem.20170484
Published: 25 June 2018
View article titled, JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia
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Includes: Supplementary data
Journal Articles

The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

Marc R. Mansour, Takaomi Sanda, Lee N. Lawton, Xiaoyu Li, Taras Kreslavsky, Carl D. Novina, Marjorie Brand, Alejandro Gutierrez, Michelle A. Kelliher, Catriona H.M. Jamieson, Harald von Boehmer, Richard A. Young, A. Thomas Look
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (8): 1545–1557.
DOI: https://doi.org/10.1084/jem.20122516
Published: 15 July 2013
View article titled, The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia
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Journal Articles

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

Daniel R. Beisner, Petra Langerak, Albert E. Parker, Carol Dahlberg, Francella J. Otero, Sue E. Sutton, Laurent Poirot, Whitney Barnes, Michael A. Young, Sherry Niessen, Tim Wiltshire, Ursula Bodendorf, Bruno Martoglio, Benjamin Cravatt, Michael P. Cooke
Journal: Journal of Experimental Medicine
J Exp Med (2012) 210 (1): 23–30.
DOI: https://doi.org/10.1084/jem.20121072
Published: 24 December 2012
View article titled, The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain
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Includes: Supplementary data
Journal Articles

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

Zachary J. Roberts, Nadege Goutagny, Pin-Yu Perera, Hiroki Kato, Himanshu Kumar, Taro Kawai, Shizuo Akira, Ram Savan, David van Echo, Katherine A. Fitzgerald, Howard A. Young, Lai-Ming Ching, Stefanie N. Vogel
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (7): 1559–1569.
DOI: https://doi.org/10.1084/jem.20061845
Published: 11 June 2007
View article titled, The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis
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Includes: Supplementary data
Journal Articles

Role of Natural Killer Cells in Innate Protection against Lethal Ebola Virus Infection

Kelly L. Warfield, Jeremy G. Perkins, Dana L. Swenson, Emily M. Deal, Catharine M. Bosio, M. Javad Aman, Wayne M. Yokoyama, Howard A. Young, Sina Bavari
Journal: Journal of Experimental Medicine
J Exp Med (2004) 200 (2): 169–179.
DOI: https://doi.org/10.1084/jem.20032141
Published: 12 July 2004
View article titled, Role of Natural Killer Cells in Innate Protection against Lethal Ebola Virus Infection
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Journal Articles

The Four Distal Tyrosines Are Required for LAT-dependent Signaling in FcεRI-mediated Mast Cell Activation

Shin-ichiroh Saitoh, Sandra Odom, Gregorio Gomez, Connie L. Sommers, Howard A. Young, Juan Rivera, Lawrence E. Samelson
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (5): 831–843.
DOI: https://doi.org/10.1084/jem.20030574
Published: 02 September 2003
View article titled, The Four Distal Tyrosines Are Required for LAT-dependent Signaling in FcεRI-mediated Mast Cell Activation
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Journal Articles

Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 Cells

Andrea L. Wurster, Vikki L. Rodgers, Abhay R. Satoskar, Matthew J. Whitters, Deborah A. Young, Mary Collins, Michael J. Grusby
Journal: Journal of Experimental Medicine
J Exp Med (2002) 196 (7): 969–977.
DOI: https://doi.org/10.1084/jem.20020620
Published: 30 September 2002
View article titled, Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 Cells
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Journal Articles

In Vivo Cytotoxic T Lymphocyte Elicitation by Mycobacterial Heat Shock Protein 70 Fusion Proteins Maps to a Discrete Domain and Is Cd4+ T Cell Independent

Qian Huang, Joan F.L. Richmond, Kimiko Suzue, Herman N. Eisen, Richard A. Young
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (2): 403–408.
DOI: https://doi.org/10.1084/jem.191.2.403
Published: 17 January 2000
View article titled, In Vivo Cytotoxic T Lymphocyte Elicitation by Mycobacterial Heat Shock Protein 70 Fusion Proteins Maps to a Discrete Domain and Is Cd4<sup>+</sup> T Cell Independent
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Journal Articles

Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts

Xinping Zhang, Scott G. Morham, Robert Langenbach, Donald A. Young
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (4): 451–460.
DOI: https://doi.org/10.1084/jem.190.4.451
Published: 16 August 1999
View article titled, Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts
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Journal Articles

Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)

L H Mason, J R Ortaldo, H A Young, V Kumar, M Bennett, S K Anderson
Journal: Journal of Experimental Medicine
J Exp Med (1995) 182 (2): 293–303.
DOI: https://doi.org/10.1084/jem.182.2.293
Published: 01 August 1995
View article titled, Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)
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Journal Articles

Presentation by a major histocompatibility complex class I molecule of nucleoprotein peptide expressed in two different genes of an influenza virus transfectant.

H Isobe, T Moran, S Li, A Young, S Nathenson, P Palese, C Bona
Journal: Journal of Experimental Medicine
J Exp Med (1995) 181 (1): 203–213.
DOI: https://doi.org/10.1084/jem.181.1.203
Published: 01 January 1995
View article titled, Presentation by a major histocompatibility complex class I molecule of nucleoprotein peptide expressed in two different genes of an influenza virus transfectant.
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Journal Articles

Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1.

T J Tsomides, A Aldovini, R P Johnson, B D Walker, R A Young, H N Eisen
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (4): 1283–1293.
DOI: https://doi.org/10.1084/jem.180.4.1283
Published: 01 October 1994
View article titled, Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1.
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Journal Articles

Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells.

L Penix, W M Weaver, Y Pang, H A Young, C B Wilson
Journal: Journal of Experimental Medicine
J Exp Med (1993) 178 (5): 1483–1496.
DOI: https://doi.org/10.1084/jem.178.5.1483
Published: 01 November 1993
View article titled, Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells.
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Journal Articles

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

S H Chan, B Perussia, J W Gupta, M Kobayashi, M Pospísil, H A Young, S F Wolf, D Young, S C Clark, G Trinchieri
Journal: Journal of Experimental Medicine
J Exp Med (1991) 173 (4): 869–879.
DOI: https://doi.org/10.1084/jem.173.4.869
Published: 01 April 1991
View article titled, Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.
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Journal Articles

A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytes.

J C Chrivia, T Wedrychowicz, H A Young, K J Hardy
Journal: Journal of Experimental Medicine
J Exp Med (1990) 172 (2): 661–664.
DOI: https://doi.org/10.1084/jem.172.2.661
Published: 01 August 1990
View article titled, A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytes.
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Journal Articles

Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.

M J Smyth, J R Ortaldo, Y Shinkai, H Yagita, M Nakata, K Okumura, H A Young
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (4): 1269–1281.
DOI: https://doi.org/10.1084/jem.171.4.1269
Published: 01 April 1990
View article titled, Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.
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Journal Articles

Interleukin 2-induced proliferation of murine natural killer cells in vivo.

C A Biron, H A Young, M T Kasaian
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (1): 173–188.
DOI: https://doi.org/10.1084/jem.171.1.173
Published: 01 January 1990
View article titled, Interleukin 2-induced proliferation of murine natural killer cells in vivo.
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Journal Articles

Lack of gene rearrangement and mRNA expression of the beta chain of the T cell receptor in spontaneous rat large granular lymphocyte leukemia lines.

C W Reynolds, M Bonyhadi, R B Herberman, H A Young, S M Hedrick
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (5): 1249–1254.
DOI: https://doi.org/10.1084/jem.161.5.1249
Published: 01 May 1985
View article titled, Lack of gene rearrangement and mRNA expression of the beta chain of the T cell receptor in spontaneous rat large granular lymphocyte leukemia lines.
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Journal Articles

TRANSMISSION OF SWINE INFLUENZA VIRUS BY LUNGWORM MIGRATION

H. G. Sen, G. W. Kelley, N. R. Underdahl, G. A. Young
Journal: Journal of Experimental Medicine
J Exp Med (1961) 113 (3): 517–520.
DOI: https://doi.org/10.1084/jem.113.3.517
Published: 01 March 1961
View article titled, TRANSMISSION OF SWINE INFLUENZA VIRUS BY LUNGWORM MIGRATION
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