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David A. Tuveson
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Journal Articles

Pancreatic cancer SLUGged

Rachel H. Josselsohn, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (9): e20200819.
DOI: https://doi.org/10.1084/jem.20200819
Published: 18 August 2020
View article titled, Pancreatic cancer SLUGged
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Journal Articles

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

In Special Collection:
JEM Cancer Collection 2021 , Mechanisms and Models of Cancer , Metabolism in Homeostasis and Disease
Tobiloba E. Oni, Giulia Biffi, Lindsey A. Baker, Yuan Hao, Claudia Tonelli, Tim D.D. Somerville, Astrid Deschênes, Pascal Belleau, Chang-il Hwang, Francisco J. Sánchez-Rivera, Hilary Cox, Erin Brosnan, Abhishek Doshi, Rebecca P. Lumia, Kimia Khaledi, Youngkyu Park, Lloyd C. Trotman, Scott W. Lowe, Alexander Krasnitz, Christopher R. Vakoc, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (9): e20192389.
DOI: https://doi.org/10.1084/jem.20192389
Published: 07 July 2020
View article titled, SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
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Includes: Supplementary data
Journal Articles

SIRT1–NOX4 signaling axis regulates cancer cachexia

In Special Collection:
Mechanisms and Models of Cancer
Aneesha Dasgupta, Surendra K. Shukla, Enza Vernucci, Ryan J. King, Jaime Abrego, Scott E. Mulder, Nicholas J. Mullen, Gavin Graves, Kyla Buettner, Ravi Thakur, Divya Murthy, Kuldeep S. Attri, Dezhen Wang, Nina V. Chaika, Camila G. Pacheco, Ibha Rai, Dannielle D. Engle, Paul M. Grandgenett, Michael Punsoni, Bradley N. Reames, Melissa Teoh-Fitzgerald, Rebecca Oberley-Deegan, Fang Yu, Kelsey A. Klute, Michael A. Hollingsworth, Matthew C. Zimmerman, Kamiya Mehla, Junichi Sadoshima, David A. Tuveson, Pankaj K. Singh
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (7): e20190745.
DOI: https://doi.org/10.1084/jem.20190745
Published: 22 May 2020
View article titled, SIRT1–NOX4 signaling axis regulates cancer cachexia
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Includes: Supplementary data
Journal Articles

Deciphering cancer fibroblasts

Giulia Biffi, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (12): 2967–2968.
DOI: https://doi.org/10.1084/jem.20182069
Published: 23 November 2018
View article titled, Deciphering cancer fibroblasts
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Journal Articles

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

In Special Collection:
2017: The Year in Experimental Medicine , Cancer 2018 , Cancer Plasticity and Heterogeneity
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S. Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E. Oni, Stephen A. Hearn, Eun Jung Lee, Iok In Christine Chio, Chang-Il Hwang, Hervé Tiriac, Lindsey A. Baker, Dannielle D. Engle, Christine Feig, Anne Kultti, Mikala Egeblad, Douglas T. Fearon, James M. Crawford, Hans Clevers, Youngkyu Park, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (3): 579–596.
DOI: https://doi.org/10.1084/jem.20162024
Published: 23 February 2017
View article titled, Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
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Includes: Supplementary data
Journal Articles

Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia

Edward W. Roberts, Andrew Deonarine, James O. Jones, Alice E. Denton, Christine Feig, Scott K. Lyons, Marion Espeli, Matthew Kraman, Brendan McKenna, Richard J.B. Wells, Qi Zhao, Otavia L. Caballero, Rachel Larder, Anthony P. Coll, Stephen O’Rahilly, Kevin M. Brindle, Sarah A. Teichmann, David A. Tuveson, Douglas T. Fearon
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (6): 1137–1151.
DOI: https://doi.org/10.1084/jem.20122344
Published: 27 May 2013
View article titled, Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
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Includes: Supplementary data
Journal Articles

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

Natalie Cook, Kristopher K. Frese, Tashinga E. Bapiro, Michael A. Jacobetz, Aarthi Gopinathan, Jodi L. Miller, Sudhir S. Rao, Tim Demuth, William J. Howat, Duncan I. Jodrell, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (3): 437–444.
DOI: https://doi.org/10.1084/jem.20111923
Published: 20 February 2012
View article titled, Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma
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