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Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection

Carlos Diaz-Salazar, Regina Bou-Puerto, Adriana M. Mujal, Colleen M. Lau, Madlaina von Hoesslin, Dietmar Zehn, Joseph C. Sun

J Exp Med (2020) 217 (4): e20190549.

DOI: https://doi.org/10.1084/jem.20190549

Published: 11 February 2020

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Journal Articles

pMHC affinity controls duration of CD8⁺ T cell–DC interactions and imprints timing of effector differentiation versus expansion

Aleksandra J. Ozga, Federica Moalli, Jun Abe, Jim Swoger, James Sharpe, Dietmar Zehn, Mario Kreutzfeldt, Doron Merkler, Jorge Ripoll, Jens V. Stein

J Exp Med (2016) 213 (12): 2811–2829.

DOI: https://doi.org/10.1084/jem.20160206

Published: 31 October 2016

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Includes: Supplementary data

Journal Articles

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival

Daniel T. Utzschneider, Francesca Alfei, Patrick Roelli, David Barras, Vijaykumar Chennupati, Stephanie Darbre, Mauro Delorenzi, Daniel D. Pinschewer, Dietmar Zehn

J Exp Med (2016) 213 (9): 1819–1834.

DOI: https://doi.org/10.1084/jem.20150598

Published: 25 July 2016

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Journal Articles

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

Sarah Enouz, Lucie Carrié, Doron Merkler, Michael J. Bevan, Dietmar Zehn

J Exp Med (2012) 209 (10): 1769–1779.

DOI: https://doi.org/10.1084/jem.20120905

Published: 17 September 2012

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Journal Articles

One naive T cell, multiple fates in CD8⁺ T cell differentiation

Carmen Gerlach, Jeroen W.J. van Heijst, Erwin Swart, Daoud Sie, Nicola Armstrong, Ron M. Kerkhoven, Dietmar Zehn, Michael J. Bevan, Koen Schepers, Ton N.M. Schumacher

J Exp Med (2010) 207 (6): 1235–1246.

DOI: https://doi.org/10.1084/jem.20091175

Published: 17 May 2010

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Includes: Supplementary data

NARROW

Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection

pMHC affinity controls duration of CD8⁺ T cell–DC interactions and imprints timing of effector differentiation versus expansion

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

One naive T cell, multiple fates in CD8⁺ T cell differentiation

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Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection

pMHC affinity controls duration of CD8+ T cell–DC interactions and imprints timing of effector differentiation versus expansion

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

One naive T cell, multiple fates in CD8+ T cell differentiation

Email alerts

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pMHC affinity controls duration of CD8⁺ T cell–DC interactions and imprints timing of effector differentiation versus expansion

One naive T cell, multiple fates in CD8⁺ T cell differentiation