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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8⁺ T cell dysfunction in melanoma patients

Julien Fourcade, Zhaojun Sun, Mourad Benallaoua, Philippe Guillaume, Immanuel F. Luescher, Cindy Sander, John M. Kirkwood, Vijay Kuchroo, Hassane M. Zarour

J Exp Med (2010) 207 (10): 2175–2186.

DOI: https://doi.org/10.1084/jem.20100637

Published: 06 September 2010

View article titled, Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

Includes: Supplementary data

Journal Articles

CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56^lck Complexes

Alexandre Arcaro, Claude Grégoire, Talitha R. Bakker, Lucia Baldi, Martin Jordan, Laurence Goffin, Nicole Boucheron, Florian Wurm, P. Anton van der Merwe, Bernard Malissen, Immanuel F. Luescher

J Exp Med (2001) 194 (10): 1485–1495.

DOI: https://doi.org/10.1084/jem.194.10.1485

Published: 19 November 2001

View article titled, CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56lck Complexes

Journal Articles

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Benedikt Kessler, Denis Hudrisier, Jean-Charles Cerottini, Immanuel F. Luescher

J Exp Med (1997) 186 (12): 2033–2038.

DOI: https://doi.org/10.1084/jem.186.12.2033

Published: 15 December 1997

View article titled, Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Journal Articles

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2K^d–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

Benedikt M. Kessler, Paolo Bassanini, Jean-Charles Cerottini, Immanuel F. Luescher

J Exp Med (1997) 185 (4): 629–640.

DOI: https://doi.org/10.1084/jem.185.4.629

Published: 17 February 1997

View article titled, Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2Kd–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

Journal Articles

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

Valery Renard, Pedro Romero, Eric Vivier, Bernard Malissen, Immanuel F. Luescher

J Exp Med (1996) 184 (6): 2439–2444.

DOI: https://doi.org/10.1084/jem.184.6.2439

Published: 01 December 1996

View article titled, CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

NARROW

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8⁺ T cell dysfunction in melanoma patients

CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56^lck Complexes

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2K^d–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56lck Complexes

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2Kd–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

Email alerts

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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8⁺ T cell dysfunction in melanoma patients

CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56^lck Complexes

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2K^d–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative