Search Results | Journal of Experimental Medicine

1-19 of 19

Sort by

Sort Order Select

Journal Articles

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

Eric J. Wigton, Yohei Mikami, Ryan J. McMonigle, Carlos A. Castellanos, Adam K. Wade-Vallance, Simon K. Zhou, Robin Kageyama, Adam Litterman, Suparna Roy, Daisuke Kitamura, Emily C. Dykhuizen, Christopher D.C. Allen, Hui Hu, John J. O’Shea, K. Mark Ansel

J Exp Med (2021) 218 (11): e20201422.

DOI: https://doi.org/10.1084/jem.20201422

Published: 29 September 2021

View article

Journal Articles

Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

In Special Collection:

JEM Hematologic Malignancies Collection 2021

Raud Razzaghi, Shreya Agarwal, Nikita Kotlov, Olga Plotnikova, Krystle Nomie, Da Wei Huang, George W. Wright, Grace A. Smith, Moyi Li, Katsuyoshi Takata, Maryam Yamadi, Chen Yao, John J. O’Shea, James D. Phelan, Stefania Pittaluga, David W. Scott, Jagan R. Muppidi

J Exp Med (2020) 218 (3): e20201173.

DOI: https://doi.org/10.1084/jem.20201173

Published: 25 November 2020

View article

Includes: Supplementary data

Journal Articles

Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells

Alejandro V. Villarino, Giuseppe Sciumè, Fred P. Davis, Shigeru Iwata, Beatrice Zitti, Gertraud W. Robinson, Lothar Hennighausen, Yuka Kanno, John J. O’Shea

J Exp Med (2017) 214 (10): 2999–3014.

DOI: https://doi.org/10.1084/jem.20150907

Published: 15 September 2017

View article

Includes: Supplementary data

Journal Articles

IL-27 shakes up the establishment of ectopic lymphoid structures

Alejandro V. Villarino, John J. O’Shea, Christopher A. Hunter

J Exp Med (2015) 212 (11): 1757.

DOI: https://doi.org/10.1084/jem.21211insight4

Published: 19 October 2015

View article

Journal Articles

Distinct requirements for T-bet in gut innate lymphoid cells

Giuseppe Sciumé, Kiyoshi Hirahara, Hayato Takahashi, Arian Laurence, Alejandro V. Villarino, Kentner L. Singleton, Sean P. Spencer, Christoph Wilhelm, Amanda C. Poholek, Golnaz Vahedi, Yuka Kanno, Yasmine Belkaid, John J. O'Shea

J Exp Med (2012) 209 (13): 2331–2338.

DOI: https://doi.org/10.1084/jem.20122097

Published: 03 December 2012

View article

Journal Articles

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

Hiroaki Takatori, Yuka Kanno, Wendy T. Watford, Cristina M. Tato, Greta Weiss, Ivaylo I. Ivanov, Dan R. Littman, John J. O'Shea

J Exp Med (2008) 206 (1): 35–41.

DOI: https://doi.org/10.1084/jem.20072713

Published: 29 December 2008

View article

Includes: Supplementary data

Journal Articles

Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii

Wendy T. Watford, Bruce D. Hissong, Lydia R. Durant, Hidehiro Yamane, Linda M. Muul, Yuka Kanno, Cristina M. Tato, Haydeé L. Ramos, Alan E. Berger, Lisa Mielke, Marko Pesu, Benjamin Solomon, David M. Frucht, William E. Paul, Alan Sher, Dragana Jankovic, Philip N. Tsichlis, John J. O'Shea

J Exp Med (2008) 205 (12): 2803–2812.

DOI: https://doi.org/10.1084/jem.20081461

Published: 10 November 2008

View article

Includes: Supplementary data

Journal Articles

CD4⁺FoxP3⁺ regulatory T cells confer infectious tolerance in a TGF-β–dependent manner

John Andersson, Dat Q. Tran, Marko Pesu, Todd S. Davidson, Heather Ramsey, John J. O'Shea, Ethan M. Shevach

J Exp Med (2008) 205 (9): 1975–1981.

DOI: https://doi.org/10.1084/jem.20080308

Published: 18 August 2008

View article

Includes: Supplementary data

Journal Articles

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

Alejandro V. Villarino, Cristina M. Tato, Jason S. Stumhofer, Zhengju Yao, Yongzhi K. Cui, Lothar Hennighausen, John J. O'Shea, Christopher A. Hunter

J Exp Med (2007) 204 (1): 65–71.

DOI: https://doi.org/10.1084/jem.20061198

Published: 16 January 2007

View article

Includes: Supplementary data

Journal Articles

Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!

Cristina M. Tato, Arian Laurence, John J. O'Shea

J Exp Med (2006) 203 (4): 809–812.

DOI: https://doi.org/10.1084/jem.20060522

Published: 10 April 2006

View article

Journal Articles

Correction

Takashi Usui, Jan C. Preiss, Yuka Kanno, Zheng Ju Yao, Jay H. Bream, John J. O'Shea, Warren Strober

J Exp Med (2006) 203 (4): 1129.

DOI: https://doi.org/10.1084/jem.20052165030906c

Published: 20 March 2006

View article

Journal Articles

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

Takashi Usui, Jan C. Preiss, Yuka Kanno, Zheng Ju Yao, Jay H. Bream, John J. O'Shea, Warren Strober

J Exp Med (2006) 203 (3): 755–766.

DOI: https://doi.org/10.1084/jem.20052165

Published: 06 March 2006

View article

Includes: Supplementary data

Journal Articles

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction.

F Candotti, S A Oakes, J A Johnston, L D Notarangelo, J J O'Shea, R M Blaese

J Exp Med (1996) 183 (6): 2687–2692.

DOI: https://doi.org/10.1084/jem.183.6.2687

Published: 01 June 1996

View article

Journal Articles

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7.

T Musso, J A Johnston, D Linnekin, L Varesio, T K Rowe, J J O'Shea, D W McVicar

J Exp Med (1995) 181 (4): 1425–1431.

DOI: https://doi.org/10.1084/jem.181.4.1425

Published: 01 April 1995

View article

Journal Articles

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

C M Bacon, D W McVicar, J R Ortaldo, R C Rees, J J O'Shea, J A Johnston

J Exp Med (1995) 181 (1): 399–404.

DOI: https://doi.org/10.1084/jem.181.1.399

Published: 01 January 1995

View article

Journal Articles

Receptor-induced death in human natural killer cells: involvement of CD16.

J R Ortaldo, A T Mason, J J O'Shea

J Exp Med (1995) 181 (1): 339–344.

DOI: https://doi.org/10.1084/jem.181.1.339

Published: 01 January 1995

View article

Journal Articles

IL-4 and IL-13 induce Lsk, a Csk-like tyrosine kinase, in human monocytes.

T Musso, L Varesio, X Zhang, T K Rowe, P Ferrara, J R Ortaldo, J J O'Shea, D W McVicar

J Exp Med (1994) 180 (6): 2383–2388.

DOI: https://doi.org/10.1084/jem.180.6.2383

Published: 01 December 1994

View article

Journal Articles

Connective tissue proteins and phagocytic cell function. Laminin enhances complement and Fc-mediated phagocytosis by cultured human macrophages.

J F Bohnsack, H K Kleinman, T Takahashi, J J O'Shea, E J Brown

J Exp Med (1985) 161 (5): 912–923.

DOI: https://doi.org/10.1084/jem.161.5.912

Published: 01 May 1985

View article

Journal Articles

Studies on the fibronectin receptors of human peripheral blood leukocytes. Morphologic and functional characterization.

C G Pommier, J O'Shea, T Chused, K Yancey, M M Frank, T Takahashi, E J Brown

J Exp Med (1984) 159 (1): 137–151.

DOI: https://doi.org/10.1084/jem.159.1.137

Published: 01 January 1984

View article

NARROW

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells

IL-27 shakes up the establishment of ectopic lymphoid structures

Distinct requirements for T-bet in gut innate lymphoid cells

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii

CD4⁺FoxP3⁺ regulatory T cells confer infectious tolerance in a TGF-β–dependent manner

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!

Correction

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction.

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7.

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

Receptor-induced death in human natural killer cells: involvement of CD16.

IL-4 and IL-13 induce Lsk, a Csk-like tyrosine kinase, in human monocytes.

Connective tissue proteins and phagocytic cell function. Laminin enhances complement and Fc-mediated phagocytosis by cultured human macrophages.

Studies on the fibronectin receptors of human peripheral blood leukocytes. Morphologic and functional characterization.

Email alerts

Email alerts

This Feature Is Available To Subscribers Only