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Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer⁺ CD8⁺ T Cells in Humans

Valérie Dutoit, Verena Rubio-Godoy, Mikäel J. Pittet, Alfred Zippelius, Pierre-Yves Dietrich, Frédérique Anne Legal, Philippe Guillaume, Pedro Romero, Jean-Charles Cerottini, Richard A. Houghten, Clemencia Pinilla, Danila Valmori

J Exp Med (2002) 196 (2): 207–216.

DOI: https://doi.org/10.1084/jem.20020242

Published: 15 July 2002

View article titled, Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer+ CD8+ T Cells in Humans

Journal Articles

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Alfred Zippelius, Mikaël J. Pittet, Pascal Batard, Nathalie Rufer, Magda de Smedt, Philippe Guillaume, Kim Ellefsen, Danila Valmori, Danielle Liénard, Jean Plum, H. Robson MacDonald, Daniel E. Speiser, Jean-Charles Cerottini, Pedro Romero

J Exp Med (2002) 195 (4): 485–494.

DOI: https://doi.org/10.1084/jem.20011658

Published: 19 February 2002

View article titled, Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Journal Articles

Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells

Frederic Berard, Patrick Blanco, Jean Davoust, Eve-Marie Neidhart-Berard, Mahyar Nouri-Shirazi, Nicolas Taquet, Donata Rimoldi, Jean Charles Cerottini, Jacques Banchereau, A. Karolina Palucka

J Exp Med (2000) 192 (11): 1535–1544.

DOI: https://doi.org/10.1084/jem.192.11.1535

Published: 27 November 2000

View article titled, Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells

Journal Articles

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

Daniel E. Speiser, Mikaël J. Pittet, Danila Valmori, Rod Dunbar, Donata Rimoldi, Danielle Liénard, H. Robson MacDonald, Jean-Charles Cerottini, Vincenzo Cerundolo, Pedro Romero

J Exp Med (1999) 190 (6): 775–782.

DOI: https://doi.org/10.1084/jem.190.6.775

Published: 20 September 1999

View article titled, In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

Journal Articles

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8⁺ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

Mikaël J. Pittet, Danila Valmori, P. Rod Dunbar, Daniel E. Speiser, Danielle Liénard, Ferdy Lejeune, Katharina Fleischhauer, Vincenzo Cerundolo, Jean-Charles Cerottini, Pedro Romero

J Exp Med (1999) 190 (5): 705–716.

DOI: https://doi.org/10.1084/jem.190.5.705

Published: 06 September 1999

View article titled, High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

Journal Articles

Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3

Danila Valmori, Uzi Gileadi, Catherine Servis, P. Rod Dunbar, Jean-Charles Cerottini, Pedro Romero, Vincenzo Cerundolo, Frédéric Lévy

J Exp Med (1999) 189 (6): 895–906.

DOI: https://doi.org/10.1084/jem.189.6.895

Published: 15 March 1999

View article titled, Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3

Journal Articles

Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

Pedro Romero, P. Rod Dunbar, Danila Valmori, Mikaël Pittet, Graham S. Ogg, Donata Rimoldi, Ji-Li Chen, Danielle Liénard, Jean-Charles Cerottini, Vincenzo Cerundolo

J Exp Med (1998) 188 (9): 1641–1650.

DOI: https://doi.org/10.1084/jem.188.9.1641

Published: 02 November 1998

View article titled, Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

Journal Articles

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Benedikt Kessler, Denis Hudrisier, Jean-Charles Cerottini, Immanuel F. Luescher

J Exp Med (1997) 186 (12): 2033–2038.

DOI: https://doi.org/10.1084/jem.186.12.2033

Published: 15 December 1997

View article titled, Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Journal Articles

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2K^d–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

Benedikt M. Kessler, Paolo Bassanini, Jean-Charles Cerottini, Immanuel F. Luescher

J Exp Med (1997) 185 (4): 629–640.

DOI: https://doi.org/10.1084/jem.185.4.629

Published: 17 February 1997

View article titled, Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2Kd–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

Journal Articles

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : III. Velocity Sedimentation Studies of the Differentiation and Fate of Effector Cells in Long-Term Mixed Leukocyte Cultures

H. Robson MacDonald, Jean-Charles Cerottini, K. Theodor Brunner

J Exp Med (1974) 140 (6): 1511–1521.

DOI: https://doi.org/10.1084/jem.140.6.1511

Published: 01 December 1974

View article titled, GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : III. Velocity Sedimentation Studies of the Differentiation and Fate of Effector Cells in Long-Term Mixed Leukocyte Cultures

Journal Articles

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES

H. Robson MacDonald, Howard D. Engers, Jean-Charles Cerottini, K. Theodor Brunner

J Exp Med (1974) 140 (3): 718–730.

DOI: https://doi.org/10.1084/jem.140.3.718

Published: 01 September 1974

View article titled, GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES

Journal Articles

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : I. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN CELLS IN MIXED LEUKOCYTE CULTURES

Jean-Charles Cerottini, Howard D. Engers, H. Robson MacDonald, K. Theodor Brunner

J Exp Med (1974) 140 (3): 703–717.

DOI: https://doi.org/10.1084/jem.140.3.703

Published: 01 September 1974

View article titled, GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : I. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN CELLS IN MIXED LEUKOCYTE CULTURES

Journal Articles

THYMUS-DERIVED (T) CELL IMMUNOGLOBULINS : PRESENCE OF A RECEPTOR SITE FOR IGG AND ABSENCE OF LARGE AMOUNTS OF "BURIED" IG DETERMINANTS ON T CELLS

Howard M. Grey, Ralph T. Kubo, Jean-Charles Cerottini

J Exp Med (1972) 136 (5): 1323–1328.

DOI: https://doi.org/10.1084/jem.136.5.1323

Published: 01 November 1972

View article titled, THYMUS-DERIVED (T) CELL IMMUNOGLOBULINS : PRESENCE OF A RECEPTOR SITE FOR IGG AND ABSENCE OF LARGE AMOUNTS OF "BURIED" IG DETERMINANTS ON T CELLS

Journal Articles

THE IMMUNOGENICITY OF ANTIGEN BOUND TO THE PLASMA MEMBRANE OF MACROPHAGES

Emil R. Unanue, Jean-Charles Cerottini

J Exp Med (1970) 131 (4): 711–725.

DOI: https://doi.org/10.1084/jem.131.4.711

Published: 01 April 1970

View article titled, THE IMMUNOGENICITY OF ANTIGEN BOUND TO THE PLASMA MEMBRANE OF MACROPHAGES

Journal Articles

COMPARISON OF THE IMMUNE RESPONSIVENESS OF NZB AND NZB x NZW F₁ HYBRID MICE WITH THAT OF OTHER STRAINS OF MICE

Jean-Charles Cerottini, Paul-Henri Lambert, Frank J. Dixon

J Exp Med (1969) 130 (5): 1093–1105.

DOI: https://doi.org/10.1084/jem.130.5.1093

Published: 01 November 1969

View article titled, COMPARISON OF THE IMMUNE RESPONSIVENESS OF NZB AND NZB x NZW F1 HYBRID MICE WITH THAT OF OTHER STRAINS OF MICE

Journal Articles

AN APPROACH TO THE QUANTITATION OF IMMUNOGENIC ANTIGEN

Patricia J. McConahey, Jean-Charles Cerottini, Frank J. Dixon

J Exp Med (1968) 127 (5): 1003–1011.

DOI: https://doi.org/10.1084/jem.127.5.1003

Published: 01 May 1968

View article titled, AN APPROACH TO THE QUANTITATION OF IMMUNOGENIC ANTIGEN

NARROW

Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer⁺ CD8⁺ T Cells in Humans

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8⁺ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3

Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes

Effects of Epitope Modification on T Cell Receptor–Ligand Binding and Antigen Recognition by Seven H-2K^d–restricted Cytotoxic T Lymphocyte Clones Specific for a Photoreactive Peptide Derivative

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : III. Velocity Sedimentation Studies of the Differentiation and Fate of Effector Cells in Long-Term Mixed Leukocyte Cultures

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : I. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN CELLS IN MIXED LEUKOCYTE CULTURES

THYMUS-DERIVED (T) CELL IMMUNOGLOBULINS : PRESENCE OF A RECEPTOR SITE FOR IGG AND ABSENCE OF LARGE AMOUNTS OF "BURIED" IG DETERMINANTS ON T CELLS

THE IMMUNOGENICITY OF ANTIGEN BOUND TO THE PLASMA MEMBRANE OF MACROPHAGES

COMPARISON OF THE IMMUNE RESPONSIVENESS OF NZB AND NZB x NZW F₁ HYBRID MICE WITH THAT OF OTHER STRAINS OF MICE

AN APPROACH TO THE QUANTITATION OF IMMUNOGENIC ANTIGEN

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