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Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

In Special Collection:

2021: The Year in Experimental Medicine , Cardiovascular Biology 2021 , JEM Stroke Immunology Collection 2022

Frank M. Davis, Lam C. Tsoi, William J. Melvin, Aaron denDekker, Rachael Wasikowski, Amrita D. Joshi, Sonya Wolf, Andrea T. Obi, Allison C. Billi, Xianying Xing, Christopher Audu, Bethany B. Moore, Steven L. Kunkel, Alan Daugherty, Hong S. Lu, Johann E. Gudjonsson, Katherine A. Gallagher

J Exp Med (2021) 218 (6): e20201839.

https://doi.org/10.1084/jem.20201839

Published: 29 March 2021

View article titled, Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

Includes: Supplementary data

Journal Articles

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

Jeremy Juang, Peter J.R. Ebert, Dan Feng, K. Christopher Garcia, Michelle Krogsgaard, Mark M. Davis

J Exp Med (2010) 207 (6): 1223–1234.

https://doi.org/10.1084/jem.20092170

Published: 10 May 2010

View article titled, Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

Includes: Supplementary data

Journal Articles

Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses

Bebhinn Treanor, Peter M.P. Lanigan, Sunil Kumar, Chris Dunsby, Ian Munro, Egidijus Auksorius, Fiona J. Culley, Marco A. Purbhoo, David Phillips, Mark A.A. Neil, Deborah N. Burshtyn, Paul M.W. French, Daniel M. Davis

J Exp Med (2006) 203 (7): i19.

https://doi.org/10.1084/JEM2037OIA19

Published: 10 July 2006

Journal Articles

Erratum

Hongyan Wang, Fiona E. McCann, John D. Gordan, Xiang Wu, Eun-Yi Moon, Monika Raab, Talat H. Malik, Daniel M. Davis, Christopher E. Rudd

J Exp Med (2005) 201 (4): 659.

https://doi.org/10.1084/jem.20040780020805c

Published: 22 February 2005

View article titled, Erratum

Journal Articles

ADAP–SLP-76 Binding Differentially Regulates Supramolecular Activation Cluster (SMAC) Formation Relative to T Cell–APC Conjugation

Hongyan Wang, Fiona E. McCann, John D. Gordan, Xiang Wu, Monika Raab, Talat H. Malik, Daniel M. Davis, Christopher E. Rudd

J Exp Med (2004) 200 (8): 1063–1074.

https://doi.org/10.1084/jem.20040780

Published: 11 October 2004

View article titled, ADAP–SLP-76 Binding Differentially Regulates Supramolecular Activation Cluster (SMAC) Formation Relative to T Cell–APC Conjugation

Includes: Supplementary data

Journal Articles

Cell Surface Organization of Stress-inducible Proteins ULBP and MICA That Stimulate Human NK Cells and T Cells via NKG2D

Konstantina Eleme, Sabrina B. Taner, Björn Önfelt, Lucy M. Collinson, Fiona E. McCann, N. Jan Chalupny, David Cosman, Colin Hopkins, Anthony I. Magee, Daniel M. Davis

J Exp Med (2004) 199 (7): 1005–1010.

https://doi.org/10.1084/jem.20032194

Published: 29 March 2004

View article titled, Cell Surface Organization of Stress-inducible Proteins ULBP and MICA That Stimulate Human NK Cells and T Cells via NKG2D

Journal Articles

Intercellular Transfer and Supramolecular Organization of Human Leukocyte Antigen C at Inhibitory Natural Killer Cell Immune Synapses

Leo M. Carlin, Konstantina Eleme, Fiona E. McCann, Daniel M. Davis

J Exp Med (2001) 194 (10): 1507–1517.

https://doi.org/10.1084/jem.194.10.1507

Published: 19 November 2001

View article titled, Intercellular Transfer and Supramolecular Organization of Human Leukocyte Antigen C at Inhibitory Natural Killer Cell Immune Synapses

Journal Articles

Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma: Direct Evidence of T Cell–Mediated Vitiligo

Cassian Yee, John A. Thompson, Patrick Roche, David R. Byrd, Peter P. Lee, Michael Piepkorn, Karla Kenyon, Mark M. Davis, Stanley R. Riddell, Philip D. Greenberg

J Exp Med (2000) 192 (11): 1637–1644.

https://doi.org/10.1084/jem.192.11.1637

Published: 04 December 2000

View article titled, Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma: <subtitle>Direct Evidence of T Cell–Mediated Vitiligo</subtitle>

Journal Articles

The Transmembrane Sequence of Human Histocompatibility Leukocyte Antigen (HLA)-C as a Determinant in Inhibition of a Subset of Natural Killer Cells

Daniel M. Davis, Ofer Mandelboim, Isabel Luque, Eishi Baba, Jonathan Boyson, Jack L. Strominger

J Exp Med (1999) 189 (8): 1265–1274.

https://doi.org/10.1084/jem.189.8.1265

Published: 19 April 1999

View article titled, The Transmembrane Sequence of Human Histocompatibility Leukocyte Antigen (HLA)-C as a Determinant in Inhibition of a Subset of Natural Killer Cells

Journal Articles

The Avidity Spectrum of T Cell Receptor Interactions Accounts for T Cell Anergy in a Double Transgenic Model

Laila Girgis, Mark M. Davis, Barbara Fazekas de St. Groth

J Exp Med (1999) 189 (2): 265–278.

https://doi.org/10.1084/jem.189.2.265

Published: 18 January 1999

View article titled, The Avidity Spectrum of T Cell Receptor Interactions Accounts for T Cell Anergy in a Double Transgenic Model

Journal Articles

A T Cell Receptor–specific Blockade of Positive Selection

Kristin K. Baldwin, Philip A. Reay, Lawren Wu, Andrew Farr, Mark M. Davis

J Exp Med (1999) 189 (1): 13–24.

https://doi.org/10.1084/jem.189.1.13

Published: 04 January 1999

View article titled, A T Cell Receptor–specific Blockade of Positive Selection

Journal Articles

Differential Effect of B Lymphocyte–induced Maturation Protein (Blimp-1) Expression on Cell Fate during B Cell Development

Eric J. Messika, Peter S. Lu, Yen-Jen Sung, Tony Yao, Jen-Tsan Chi, Yueh-hsiu Chien, Mark M. Davis

J Exp Med (1998) 188 (3): 515–525.

https://doi.org/10.1084/jem.188.3.515

Published: 03 August 1998

View article titled, Differential Effect of B Lymphocyte–induced Maturation Protein (Blimp-1) Expression on Cell Fate during B Cell Development

Journal Articles

Kinetics and Extent of T Cell Activation as Measured with the Calcium Signal

Christoph Wülfing, Joshua D. Rabinowitz, Craig Beeson, Michael D. Sjaastad, Harden M. McConnell, Mark M. Davis

J Exp Med (1997) 185 (10): 1815–1825.

https://doi.org/10.1084/jem.185.10.1815

Published: 19 May 1997

View article titled, Kinetics and Extent of T Cell Activation as Measured with the Calcium Signal

Journal Articles

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages

Peter A. Kiener, Patricia M. Davis, Gary C. Starling, Christopher Mehlin, Seymour J. Klebanoff, Jeffrey A. Ledbetter, W. Conrad Liles

J Exp Med (1997) 185 (8): 1511–1516.

https://doi.org/10.1084/jem.185.8.1511

Published: 21 April 1997

View article titled, Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages

Journal Articles

Limited role of CD28-mediated signals in T helper subset differentiation.

D R Brown, J M Green, N H Moskowitz, M Davis, C B Thompson, S L Reiner

J Exp Med (1996) 184 (3): 803–810.

https://doi.org/10.1084/jem.184.3.803

Published: 01 September 1996

View article titled, Limited role of CD28-mediated signals in T helper subset differentiation.

Journal Articles

Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface.

C Beeson, J Rabinowitz, K Tate, I Gütgemann, Y H Chien, P P Jones, M M Davis, H M McConnell

J Exp Med (1996) 184 (2): 777–782.

https://doi.org/10.1084/jem.184.2.777

Published: 01 August 1996

View article titled, Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface.

Journal Articles

Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced.

J J Boniface, D S Lyons, D A Wettstein, N L Allbritton, M M Davis

J Exp Med (1996) 183 (1): 119–126.

https://doi.org/10.1084/jem.183.1.119

Published: 01 January 1996

View article titled, Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced.

Journal Articles

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

W Y Ho, M P Cooke, C C Goodnow, M M Davis

J Exp Med (1994) 179 (5): 1539–1549.

https://doi.org/10.1084/jem.179.5.1539

Published: 01 May 1994

View article titled, Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

Journal Articles

CDR3 length in antigen-specific immune receptors.

E P Rock, P R Sibbald, M M Davis, Y H Chien

J Exp Med (1994) 179 (1): 323–328.

https://doi.org/10.1084/jem.179.1.323

Published: 01 January 1994

View article titled, CDR3 length in antigen-specific immune receptors.

Journal Articles

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

E W Ehrich, B Devaux, E P Rock, J L Jorgensen, M M Davis, Y H Chien

J Exp Med (1993) 178 (2): 713–722.

https://doi.org/10.1084/jem.178.2.713

Published: 01 August 1993

View article titled, T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

NARROW

Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses

Erratum

ADAP–SLP-76 Binding Differentially Regulates Supramolecular Activation Cluster (SMAC) Formation Relative to T Cell–APC Conjugation

Cell Surface Organization of Stress-inducible Proteins ULBP and MICA That Stimulate Human NK Cells and T Cells via NKG2D

Intercellular Transfer and Supramolecular Organization of Human Leukocyte Antigen C at Inhibitory Natural Killer Cell Immune Synapses

Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma: Direct Evidence of T Cell–Mediated Vitiligo

The Transmembrane Sequence of Human Histocompatibility Leukocyte Antigen (HLA)-C as a Determinant in Inhibition of a Subset of Natural Killer Cells

The Avidity Spectrum of T Cell Receptor Interactions Accounts for T Cell Anergy in a Double Transgenic Model

A T Cell Receptor–specific Blockade of Positive Selection

Differential Effect of B Lymphocyte–induced Maturation Protein (Blimp-1) Expression on Cell Fate during B Cell Development

Kinetics and Extent of T Cell Activation as Measured with the Calcium Signal

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages

Limited role of CD28-mediated signals in T helper subset differentiation.

Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface.

Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced.

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

CDR3 length in antigen-specific immune receptors.

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

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