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Paul Saftig
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Journal Articles

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis

Julia Bolik, Freia Krause, Marija Stevanovic, Monja Gandraß, Ilka Thomsen, Sarah-Sophie Schacht, Eva Rieser, Miryam Müller, Neele Schumacher, Jürgen Fritsch, Rielana Wichert, Eithan Galun, Juri Bergmann, Christian Röder, Clemens Schafmayer, Jan-Hendrik Egberts, Christoph Becker-Pauly, Paul Saftig, Ralph Lucius, Wulf Schneider-Brachert, Roja Barikbin, Dieter Adam, Matthias Voss, Wolfgang Hitzl, Achim Krüger, Boris Strilic, Irit Sagi, Henning Walczak, Stefan Rose-John, Dirk Schmidt-Arras
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20201039.
DOI: https://doi.org/10.1084/jem.20201039
Published: 17 December 2021
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Includes: Supplementary data
Journal Articles

The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

Janna Schneppenheim, Ralf Dressel, Susann Hüttl, Renate Lüllmann-Rauch, Michael Engelke, Kai Dittmann, Jürgen Wienands, Eeva-Liisa Eskelinen, Irm Hermans-Borgmeyer, Regina Fluhrer, Paul Saftig, Bernd Schröder
Journal: Journal of Experimental Medicine
J Exp Med (2012) 210 (1): 41–58.
DOI: https://doi.org/10.1084/jem.20121069
Published: 24 December 2012
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Journal Articles

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

Athena Chalaris, Nina Adam, Christian Sina, Philip Rosenstiel, Judith Lehmann-Koch, Peter Schirmacher, Dieter Hartmann, Joanna Cichy, Olga Gavrilova, Stefan Schreiber, Thomas Jostock, Vance Matthews, Robert Häsler, Christoph Becker, Markus F. Neurath, Karina Reiß, Paul Saftig, Jürgen Scheller, Stefan Rose-John
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (8): 1617–1624.
DOI: https://doi.org/10.1084/jem.20092366
Published: 05 July 2010
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Includes: Supplementary data
Journal Articles

Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy

Blanche Schroen, Joost J. Leenders, Arie van Erk, Anne T. Bertrand, Mirjam van Loon, Rick E. van Leeuwen, Nard Kubben, Rudy F. Duisters, Mark W. Schellings, Ben J. Janssen, Jacques J. Debets, Michael Schwake, Morten A. Høydal, Stephane Heymans, Paul Saftig, Yigal M. Pinto
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (5): 1227–1235.
DOI: https://doi.org/10.1084/jem.20070145
Published: 07 May 2007
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Includes: Supplementary data