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Scott W. Lowe
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Journal Articles

TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion

In Special Collection:
JEM Cancer Immunotherapy 2022 , JEM Cancer Collection 2022 , JEM Immunology Collection 2022 , 2022: The Year in Experimental Medicine
Mojdeh Shakiba, Paul Zumbo, Gabriel Espinosa-Carrasco, Laura Menocal, Friederike Dündar, Sandra E. Carson, Emmanuel M. Bruno, Francisco J. Sanchez-Rivera, Scott W. Lowe, Steven Camara, Richard P. Koche, Vincent P. Reuter, Nicholas D. Socci, Benjamin Whitlock, Fella Tamzalit, Morgan Huse, Matthew D. Hellmann, Daniel K. Wells, Nadine A. Defranoux, Doron Betel, Mary Philip, Andrea Schietinger
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (2): e20201966.
https://doi.org/10.1084/jem.20201966
Published: 22 December 2021
View article titled, TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion
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Journal Articles

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

In Special Collection:
JEM Cancer Collection 2021 , Mechanisms and Models of Cancer , Metabolism in Homeostasis and Disease
Tobiloba E. Oni, Giulia Biffi, Lindsey A. Baker, Yuan Hao, Claudia Tonelli, Tim D.D. Somerville, Astrid Deschênes, Pascal Belleau, Chang-il Hwang, Francisco J. Sánchez-Rivera, Hilary Cox, Erin Brosnan, Abhishek Doshi, Rebecca P. Lumia, Kimia Khaledi, Youngkyu Park, Lloyd C. Trotman, Scott W. Lowe, Alexander Krasnitz, Christopher R. Vakoc, David A. Tuveson
Journal: Journal of Experimental Medicine
J Exp Med (2020) 217 (9): e20192389.
https://doi.org/10.1084/jem.20192389
Published: 07 July 2020
View article titled, SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
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Includes: Supplementary data
Journal Articles

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

Alexandre Iannello, Thornton W. Thompson, Michele Ardolino, Scott W. Lowe, David H. Raulet
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (10): 2057–2069.
https://doi.org/10.1084/jem.20130783
Published: 16 September 2013
View article titled, p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
Open the PDF for p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells in another window
Includes: Supplementary data
Journal Articles

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia

Letetia Jones, Guangwei Wei, Sabina Sevcikova, Vernon Phan, Sachi Jain, Angell Shieh, Jasmine C. Y. Wong, Min Li, Joshua Dubansky, Mei Lin Maunakea, Rachel Ochoa, George Zhu, Thelma R. Tennant, Kevin M. Shannon, Scott W. Lowe, Michelle M. Le Beau, Scott C. Kogan
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (12): 2581–2594.
https://doi.org/10.1084/jem.20091071
Published: 08 November 2010
View article titled, Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia
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Includes: Supplementary data