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Journal Articles

Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity

In Special Collection:
Autoimmunity: From Novel Mechanisms to Treatments
Kunihiko Moriya, Tomohiro Nakano, Yoshitaka Honda, Miyuki Tsumura, Masato Ogishi, Motoshi Sonoda, Masahiko Nishitani-Isa, Takashi Uchida, Mohamed Hbibi, Yoko Mizoguchi, Masataka Ishimura, Kazushi Izawa, Takaki Asano, Fumihiko Kakuta, Daiki Abukawa, Darawan Rinchai, Peng Zhang, Naotomo Kambe, Aziz Bousfiha, Takahiro Yasumi, Bertrand Boisson, Anne Puel, Jean-Laurent Casanova, Ryuta Nishikomori, Shouichi Ohga, Satoshi Okada, Yoji Sasahara, Shigeo Kure
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (9): e20212276.
https://doi.org/10.1084/jem.20212276
Published: 05 June 2023
View article titled, Human <em>RELA</em> dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity
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Includes: Supplementary data
Journal Articles

Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation

Masahiko Nishitani-Isa, Kojiro Mukai, Yoshitaka Honda, Hiroshi Nihira, Takayuki Tanaka, Hirofumi Shibata, Kumi Kodama, Eitaro Hiejima, Kazushi Izawa, Yuri Kawasaki, Mitsujiro Osawa, Yu Katata, Sachiko Onodera, Tatsuya Watanabe, Takashi Uchida, Shigeo Kure, Junko Takita, Osamu Ohara, Megumu K. Saito, Ryuta Nishikomori, Tomohiko Taguchi, Yoji Sasahara, Takahiro Yasumi
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (6): e20211889.
https://doi.org/10.1084/jem.20211889
Published: 28 April 2022
View article titled, Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation
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Includes: Supplementary data
Journal Articles

Augmented TLR9-induced Btk activation in PIR-B–deficient B-1 cells provokes excessive autoantibody production and autoimmunity

Tomohiro Kubo, Yuki Uchida, Yuko Watanabe, Masahiro Abe, Akira Nakamura, Masao Ono, Shizuo Akira, Toshiyuki Takai
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (9): 1971–1982.
https://doi.org/10.1084/jem.20082392
Published: 17 August 2009
View article titled, Augmented TLR9-induced Btk activation in PIR-B–deficient B-1 cells provokes excessive autoantibody production and autoimmunity
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Includes: Supplementary data
Journal Articles

The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

Junji Uchida, Yasuhito Hamaguchi, Julie A. Oliver, Jeffrey V. Ravetch, Jonathan C. Poe, Karen M. Haas, Thomas F. Tedder
Journal: Journal of Experimental Medicine
J Exp Med (2004) 199 (12): 1659–1669.
https://doi.org/10.1084/jem.20040119
Published: 21 June 2004
View article titled, The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy
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Journal Articles

AIRE Functions As an E3 Ubiquitin Ligase

Daisuke Uchida, Shigetsugu Hatakeyama, Akemi Matsushima, Hongwei Han, Satoshi Ishido, Hak Hotta, Jun Kudoh, Nobuyoshi Shimizu, Vassilis Doucas, Keiichi I. Nakayama, Noriyuki Kuroda, Mitsuru Matsumoto
Journal: Journal of Experimental Medicine
J Exp Med (2004) 199 (2): 167–172.
https://doi.org/10.1084/jem.20031291
Published: 20 January 2004
View article titled, AIRE Functions As an E3 Ubiquitin Ligase
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Includes: Supplementary data
Journal Articles

Pag3/Papα/Kiaa0400, a Gtpase-Activating Protein for Adp-Ribosylation Factor (Arf), Regulates Arf6 in Fcγ Receptor–Mediated Phagocytosis of Macrophages

Hiroshi Uchida, Akiko Kondo, Yasunori Yoshimura, Yuichi Mazaki, Hisataka Sabe
Journal: Journal of Experimental Medicine
J Exp Med (2001) 193 (8): 955–966.
https://doi.org/10.1084/jem.193.8.955
Published: 16 April 2001
View article titled, Pag3/Papα/Kiaa0400, a Gtpase-Activating Protein for Adp-Ribosylation Factor (Arf), Regulates Arf6 in Fcγ Receptor–Mediated Phagocytosis of Macrophages
Open the PDF for Pag3/Papα/Kiaa0400, a Gtpase-Activating Protein for Adp-Ribosylation Factor (Arf), Regulates Arf6 in Fcγ Receptor–Mediated Phagocytosis of Macrophages in another window
Journal Articles

Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

Akemi Matsushima, Tsuneyasu Kaisho, Paul D. Rennert, Hiroyasu Nakano, Kyoko Kurosawa, Daisuke Uchida, Kiyoshi Takeda, Shizuo Akira, Mitsuru Matsumoto
Journal: Journal of Experimental Medicine
J Exp Med (2001) 193 (5): 631–636.
https://doi.org/10.1084/jem.193.5.631
Published: 05 March 2001
View article titled, Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I
Open the PDF for Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I in another window
Journal Articles

Idiopathic Pulmonary Alveolar Proteinosis as an Autoimmune Disease with Neutralizing Antibody against Granulocyte/Macrophage Colony-Stimulating Factor

Takayuki Kitamura, Naohiko Tanaka, Junichi Watanabe, Uchida, Shiro Kanegasaki, Yoshitsugu Yamada, Koh Nakata
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (6): 875–880.
https://doi.org/10.1084/jem.190.6.875
Published: 20 September 1999
View article titled, Idiopathic Pulmonary Alveolar Proteinosis as an Autoimmune Disease with Neutralizing Antibody against Granulocyte/Macrophage Colony-Stimulating Factor
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Journal Articles

Polymorphism of human minor histocompatibility antigens: T cell recognition of human minor histocompatibility peptides presented by HLA-B35 subtype molecules.

Y Beck, L Satz, Y Takamiya, S Nakayama, L Ling, Y Ishikawa, T Nagao, H Uchida, K Tokunaga, C Müller
Journal: Journal of Experimental Medicine
J Exp Med (1995) 181 (6): 2037–2048.
https://doi.org/10.1084/jem.181.6.2037
Published: 01 June 1995
View article titled, Polymorphism of human minor histocompatibility antigens: T cell recognition of human minor histocompatibility peptides presented by HLA-B35 subtype molecules.
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Journal Articles

Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.

N Uchida, I L Weissman
Journal: Journal of Experimental Medicine
J Exp Med (1992) 175 (1): 175–184.
https://doi.org/10.1084/jem.175.1.175
Published: 01 January 1992
View article titled, Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.
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Journal Articles

Monoclonal alloantibodies specific for the constant region of T cell antigen receptors.

T Tokuhisa, Y Komatsu, Y Uchida, M Taniguchi
Journal: Journal of Experimental Medicine
J Exp Med (1982) 156 (3): 888–897.
https://doi.org/10.1084/jem.156.3.888
Published: 01 September 1982
View article titled, Monoclonal alloantibodies specific for the constant region of T cell antigen receptors.
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