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W. O. Weigle
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Journal Articles

CD4+ T cell activation and tolerance induction in B cell knockout mice.

J A Phillips, C G Romball, M V Hobbs, D N Ernst, L Shultz, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1996) 183 (4): 1339–1344.
https://doi.org/10.1084/jem.183.4.1339
Published: 01 April 1996
View article titled, CD4+ T cell activation and tolerance induction in B cell knockout mice.
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Journal Articles

Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.

H Tighe, P Heaphy, S Baird, W O Weigle, D A Carson
Journal: Journal of Experimental Medicine
J Exp Med (1995) 181 (2): 599–606.
https://doi.org/10.1084/jem.181.2.599
Published: 01 February 1995
View article titled, Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.
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Journal Articles

Tolerogenicity of resting and activated B cells.

K M Gilbert, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1994) 179 (1): 249–258.
https://doi.org/10.1084/jem.179.1.249
Published: 01 January 1994
View article titled, Tolerogenicity of resting and activated B cells.
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Journal Articles

In vivo induction of tolerance in murine CD4+ cell subsets.

C G Romball, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1993) 178 (5): 1637–1644.
https://doi.org/10.1084/jem.178.5.1637
Published: 01 November 1993
View article titled, In vivo induction of tolerance in murine CD4+ cell subsets.
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Journal Articles

Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2.

M L Thoman, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1983) 157 (6): 2184–2189.
https://doi.org/10.1084/jem.157.6.2184
Published: 01 June 1983
View article titled, Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2.
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Journal Articles

Synthetic Fc peptide-mediated regulation of the immune response. I. Characterization of the immunomodulating properties of a synthetic 23-amino acid peptide derived from the sequence of the CH3 domain of human IgG1.

E L Morgan, J E Shields, C S Campbell, R L Barton, G A Koppel, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1983) 157 (3): 947–956.
https://doi.org/10.1084/jem.157.3.947
Published: 01 March 1983
View article titled, Synthetic Fc peptide-mediated regulation of the immune response. I. Characterization of the immunomodulating properties of a synthetic 23-amino acid peptide derived from the sequence of the CH3 domain of human IgG1.
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Journal Articles

Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors.

M G Goodman, D E Chenoweth, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1982) 156 (3): 912–917.
https://doi.org/10.1084/jem.156.3.912
Published: 01 September 1982
View article titled, Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors.
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Journal Articles

Deregulation of idiotype expression. Induction of tolerance in an anti-idiotypic response.

L Ortiz-Ortiz, W O Weigle, D E Parks
Journal: Journal of Experimental Medicine
J Exp Med (1982) 156 (3): 898–911.
https://doi.org/10.1084/jem.156.3.898
Published: 01 September 1982
View article titled, Deregulation of idiotype expression. Induction of tolerance in an anti-idiotypic response.
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Journal Articles

Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages.

D E Chenoweth, M G Goodman, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1982) 156 (1): 68–78.
https://doi.org/10.1084/jem.156.1.68
Published: 01 July 1982
View article titled, Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages.
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Journal Articles

Anaphylatoxin-mediated regulation of the immune response. I. C3a-mediated suppression of human and murine humoral immune responses.

E L Morgan, W O Weigle, T E Hugli
Journal: Journal of Experimental Medicine
J Exp Med (1982) 155 (5): 1412–1426.
https://doi.org/10.1084/jem.155.5.1412
Published: 01 May 1982
View article titled, Anaphylatoxin-mediated regulation of the immune response. I. C3a-mediated suppression of human and murine humoral immune responses.
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Journal Articles

Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes.

E L Morgan, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1981) 154 (3): 778–790.
https://doi.org/10.1084/jem.154.3.778
Published: 01 September 1981
View article titled, Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes.
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Journal Articles

In vitro tolerance induction of primed, IgD-negative murine spleen cells.

S M Walker, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1981) 153 (3): 653–664.
https://doi.org/10.1084/jem.153.3.653
Published: 01 March 1981
View article titled, In vitro tolerance induction of primed, IgD-negative murine spleen cells.
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Journal Articles

Regulation of Fc fragment-induced murine spleen cell proliferation.

E L Morgan, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1980) 151 (1): 1–11.
https://doi.org/10.1084/jem.151.1.1
Published: 01 January 1980
View article titled, Regulation of Fc fragment-induced murine spleen cell proliferation.
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Journal Articles

The requirement for adherent cells in the Fc fragment-induced proliferative response of murine spleen cells.

E L Morgan, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1979) 150 (2): 256–266.
https://doi.org/10.1084/jem.150.2.256
Published: 01 August 1979
View article titled, The requirement for adherent cells in the Fc fragment-induced proliferative response of murine spleen cells.
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Journal Articles

Induction and mode of action of suppressor cells generated against human gamma globulin. II. Effects of colchicine.

D E Parks, D A Shaller, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1979) 149 (5): 1168–1182.
https://doi.org/10.1084/jem.149.5.1168
Published: 01 May 1979
View article titled, Induction and mode of action of suppressor cells generated against human gamma globulin. II. Effects of colchicine.
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Journal Articles

Nonspecific activation of murine lymphocytes. VI. Mediation of synergistic interaction between T and B lymphocytes by a cell-associated, reciprocally acting lymphocyte proliferation helper.

M G Goodman, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1979) 149 (3): 644–657.
https://doi.org/10.1084/jem.149.3.644
Published: 01 March 1979
View article titled, Nonspecific activation of murine lymphocytes. VI. Mediation of synergistic interaction between T and B lymphocytes by a cell-associated, reciprocally acting lymphocyte proliferation helper.
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Journal Articles

Induction and mode of action of suppressor cells generated against human gamma globulin. I. An immunologic unresponsive state devoid of demonstrable suppressor cells.

D E Parks, M V Doyle, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1978) 148 (3): 625–638.
https://doi.org/10.1084/jem.148.3.625
Published: 01 September 1978
View article titled, Induction and mode of action of suppressor cells generated against human gamma globulin. I. An immunologic unresponsive state devoid of demonstrable suppressor cells.
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Journal Articles

Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects.

M G Goodman, D E Parks, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1978) 147 (3): 800–813.
https://doi.org/10.1084/jem.147.3.800
Published: 01 March 1978
View article titled, Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects.
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Journal Articles

Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen.

S M Walker, G C Meinke, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1977) 146 (2): 445–456.
https://doi.org/10.1084/jem.146.2.445
Published: 01 August 1977
View article titled, Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen.
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Journal Articles

B-lymphocytes activation by the Fc region of IgG.

M A Berman, W O Weigle
Journal: Journal of Experimental Medicine
J Exp Med (1977) 146 (1): 241–256.
https://doi.org/10.1084/jem.146.1.241
Published: 01 July 1977
View article titled, B-lymphocytes activation by the Fc region of IgG.
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