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Journal Articles

An engineered concealed IL-15-R elicits tumor-specific CD8⁺T cell responses through PD-1-cis delivery

In Special Collection:

JEM Cancer Immunotherapy 2022

Jiao Shen, Zhuangzhi Zou, Jingya Guo, Yueqi Cai, Diyuan Xue, Yong Liang, Wenyan Wang, Hua Peng, Yang-Xin Fu

J Exp Med (2022) 219 (12): e20220745.

https://doi.org/10.1084/jem.20220745

Published: 27 September 2022

View article titled, An engineered concealed IL-15-R elicits tumor-specific CD8+T cell responses through PD-1-cis delivery

Includes: Supplementary data

Journal Articles

Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation

In Special Collection:

Innate Immune Signaling in Disease and Homeostasis , JEM Cancer Immunotherapy 2021

Kaiting Yang, Yuzhu Hou, Yuan Zhang, Hua Liang, Anukriti Sharma, Wenxin Zheng, Liangliang Wang, Rolando Torres, Ken Tatebe, Steven J. Chmura, Sean P. Pitroda, Jack A. Gilbert, Yang-Xin Fu, Ralph R. Weichselbaum

J Exp Med (2021) 218 (3): e20201915.

https://doi.org/10.1084/jem.20201915

Published: 26 January 2021

View article titled, Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation

Journal Articles

β-Catenin regulates tumor-derived PD-L1

Chuanhui Han, Yang-Xin Fu

J Exp Med (2020) 217 (11): e20200684.

https://doi.org/10.1084/jem.20200684

Published: 27 August 2020

View article titled, β-Catenin regulates tumor-derived PD-L1

Journal Articles

Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling

In Special Collection:

2020: The Year in Experimental Medicine , Innate Immune Signaling in Disease and Homeostasis , JEM 2020 Update on Cancer Immunology and Immunotherapy , JEM Cancer Collection 2021

Yaoyao Shi, Wenxin Zheng, Kaiting Yang, Katharine G. Harris, Kaiyuan Ni, Lai Xue, Wenbin Lin, Eugene B. Chang, Ralph R. Weichselbaum, Yang-Xin Fu

J Exp Med (2020) 217 (5): e20192282.

https://doi.org/10.1084/jem.20192282

Published: 06 March 2020

View article titled, Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling

Includes: Supplementary data

Journal Articles

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

Erin C. Zook, Kevin Ramirez, Xiaohuan Guo, Grant van der Voort, Mikael Sigvardsson, Eric C. Svensson, Yang-Xin Fu, Barbara L. Kee

J Exp Med (2016) 213 (5): 687–696.

https://doi.org/10.1084/jem.20150851

Published: 11 April 2016

View article titled, The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

Includes: Supplementary data

Journal Articles

CD160 is essential for NK-mediated IFN-γ production

Tony C. Tu, Nicholas K. Brown, Tae-Jin Kim, Joanna Wroblewska, Xuanming Yang, Xiaohuan Guo, Seoyun Hyunji Lee, Vinay Kumar, Kyung-Mi Lee, Yang-Xin Fu

J Exp Med (2015) 212 (3): 415–429.

https://doi.org/10.1084/jem.20131601

Published: 23 February 2015

View article titled, CD160 is essential for NK-mediated IFN-γ production

Journal Articles

Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment

Tae-Jin Kim, Vaibhav Upadhyay, Vinay Kumar, Kyung-Mi Lee, Yang-Xin Fu

J Exp Med (2014) 211 (7): 1421–1431.

https://doi.org/10.1084/jem.20131501

Published: 09 June 2014

View article titled, Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment

Journal Articles

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

Elizabeth D. Thompson, Hilda L. Enriquez, Yang-Xin Fu, Victor H. Engelhard

J Exp Med (2010) 207 (8): 1791–1804.

https://doi.org/10.1084/jem.20092454

Published: 26 July 2010

View article titled, Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

Includes: Supplementary data

Journal Articles

Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection

Taeg S. Kim, Matthew M. Hufford, Jie Sun, Yang-Xin Fu, Thomas J. Braciale

J Exp Med (2010) 207 (6): 1161–1172.

https://doi.org/10.1084/jem.20092017

Published: 31 May 2010

View article titled, Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection

Includes: Supplementary data

Journal Articles

Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE^−/− mice

J Exp Med (2009) 206 (1): 233–248.

https://doi.org/10.1084/jem.20080752

Published: 12 January 2009

View article titled, Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE−/− mice

Includes: Supplementary data

Journal Articles

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Bin Zhang, Natalie A. Bowerman, Joseph K. Salama, Hank Schmidt, Michael T. Spiotto, Andrea Schietinger, Ping Yu, Yang-Xin Fu, Ralph R. Weichselbaum, Donald A. Rowley, David M. Kranz, Hans Schreiber

J Exp Med (2007) 204 (1): 49–55.

https://doi.org/10.1084/jem.20062056

Published: 08 January 2007

View article titled, Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Includes: Supplementary data

Journal Articles

Intratumor depletion of CD4⁺ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

Ping Yu, Youjin Lee, Wenhua Liu, Thomas Krausz, Anita Chong, Hans Schreiber, Yang-Xin Fu

J Exp Med (2005) 201 (5): 779–791.

https://doi.org/10.1084/jem.20041684

Published: 07 March 2005

View article titled, Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

Journal Articles

Lymphotoxin Is Required for Maintaining Physiological Levels of Serum IgE That Minimizes Th1-mediated Airway Inflammation

Hyung-Sik Kang, Sarah E. Blink, Robert K. Chin, Youjin Lee, Oliver Kim, Joel Weinstock, Thomas Waldschmidt, Daniel Conrad, Bohao Chen, Julian Solway, Anne I. Sperling, Yang-Xin Fu

J Exp Med (2003) 198 (11): 1643–1652.

https://doi.org/10.1084/jem.20021784

Published: 24 November 2003

View article titled, Lymphotoxin Is Required for Maintaining Physiological Levels of Serum IgE That Minimizes Th1-mediated Airway Inflammation

Journal Articles

Route of Immunization with Peptide-pulsed Dendritic Cells Controls the Distribution of Memory and Effector T Cells in Lymphoid Tissues and Determines the Pattern of Regional Tumor Control

David W. Mullins, Stacey L. Sheasley, Rebecca M. Ream, Timothy N.J. Bullock, Yang-Xin Fu, Victor H. Engelhard

J Exp Med (2003) 198 (7): 1023–1034.

https://doi.org/10.1084/jem.20021348

Published: 06 October 2003

View article titled, Route of Immunization with Peptide-pulsed Dendritic Cells Controls the Distribution of Memory and Effector T Cells in Lymphoid Tissues and Determines the Pattern of Regional Tumor Control

Includes: Supplementary data

Journal Articles

B7DC/PDL2 Promotes Tumor Immunity by a PD-1–independent Mechanism

Xingluo Liu, Jian Xin Gao, Jing Wen, Lijie Yin, Ou Li, Tao Zuo, Thomas F. Gajewski, Yang-Xin Fu, Pan Zheng, Yang Liu

J Exp Med (2003) 197 (12): 1721–1730.

https://doi.org/10.1084/jem.20022089

Published: 16 June 2003

View article titled, B7DC/PDL2 Promotes Tumor Immunity by a PD-1–independent Mechanism

Journal Articles

Complementary Role of CD4⁺ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8⁺ T Cells

Ping Yu, Michael T. Spiotto, Youjin Lee, Hans Schreiber, Yang-Xin Fu

J Exp Med (2003) 197 (8): 985–995.

https://doi.org/10.1084/jem.20021804

Published: 14 April 2003

View article titled, Complementary Role of CD4+ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8+ T Cells

Journal Articles

Reversal of Spontaneous Autoimmune Insulitis in Nonobese Diabetic Mice by Soluble Lymphotoxin Receptor

Qiang Wu, Benoît Salomon, Min Chen, Yang Wang, Lisa M. Hoffman, Jeffrey A. Bluestone, Yang-Xin Fu

J Exp Med (2001) 193 (11): 1327–1332.

https://doi.org/10.1084/jem.193.11.1327

Published: 04 June 2001

View article titled, Reversal of Spontaneous Autoimmune Insulitis in Nonobese Diabetic Mice by Soluble Lymphotoxin Receptor

Journal Articles

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

Paul D. Rennert, Paula S. Hochman, Richard A. Flavell, David D. Chaplin, Sundararajan Jayaraman, Jeffrey L. Browning, Yang-Xin Fu

J Exp Med (2001) 193 (11): 1227–1238.

https://doi.org/10.1084/jem.193.11.1227

Published: 29 May 2001

View article titled, Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

Journal Articles

The Requirement of Membrane Lymphotoxin for the Presence of Dendritic Cells in Lymphoid Tissues

Qiang Wu, Yang Wang, Jing Wang, Elizabeth O. Hedgeman, Jeffrey L. Browning, Yang-Xin Fu

J Exp Med (1999) 190 (5): 629–638.

https://doi.org/10.1084/jem.190.5.629

Published: 06 September 1999

View article titled, The Requirement of Membrane Lymphotoxin for the Presence of Dendritic Cells in Lymphoid Tissues

Journal Articles

Enhanced Growth of Primary Tumors in Cancer-Prone Mice after Immunization against the Mutant Region of an Inherited Oncoprotein

Christopher T. Siegel, Karin Schreiber, Stephen C. Meredith, Gabriele B. Beck-Engeser, David W. Lancki, Christopher A. Lazarski, Yang-Xin Fu, Donald A. Rowley, Hans Schreiber

J Exp Med (1999) 191 (11): 1945–1956.

https://doi.org/10.1084/jem.191.11.1945

Published: 06 June 1999

View article titled, Enhanced Growth of Primary Tumors in Cancer-Prone Mice after Immunization against the Mutant Region of an Inherited Oncoprotein

NARROW

An engineered concealed IL-15-R elicits tumor-specific CD8⁺T cell responses through PD-1-cis delivery

Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation

β-Catenin regulates tumor-derived PD-L1

Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

CD160 is essential for NK-mediated IFN-γ production

Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection

Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE^−/− mice

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Intratumor depletion of CD4⁺ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

Lymphotoxin Is Required for Maintaining Physiological Levels of Serum IgE That Minimizes Th1-mediated Airway Inflammation

Route of Immunization with Peptide-pulsed Dendritic Cells Controls the Distribution of Memory and Effector T Cells in Lymphoid Tissues and Determines the Pattern of Regional Tumor Control

B7DC/PDL2 Promotes Tumor Immunity by a PD-1–independent Mechanism

Complementary Role of CD4⁺ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8⁺ T Cells

Reversal of Spontaneous Autoimmune Insulitis in Nonobese Diabetic Mice by Soluble Lymphotoxin Receptor

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

The Requirement of Membrane Lymphotoxin for the Presence of Dendritic Cells in Lymphoid Tissues

Enhanced Growth of Primary Tumors in Cancer-Prone Mice after Immunization against the Mutant Region of an Inherited Oncoprotein

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