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Journal Articles

TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance

J Exp Med (2023) 220 (12): e20230944.

https://doi.org/10.1084/jem.20230944

Published: 29 September 2023

View article titled, TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance

Includes: Supplementary data

Journal Articles

Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice

J Exp Med (2023) 220 (11): e20230101.

https://doi.org/10.1084/jem.20230101

Published: 11 September 2023

View article titled, Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice

Journal Articles

Thymic mimicry: The art of imitation

Vanja Cabric, Chrysothemis C. Brown

J Exp Med (2023) 220 (10): e20231010.

https://doi.org/10.1084/jem.20231010

Published: 27 July 2023

View article titled, Thymic mimicry: The art of imitation

Journal Articles

miR-15/16 clusters restrict effector Treg cell differentiation and function

Jiayi Dong, William J. Huth, Nimi Marcel, Ziyue Zhang, Ling-Li Lin, Li-Fan Lu

J Exp Med (2023) 220 (10): e20230321.

https://doi.org/10.1084/jem.20230321

Published: 27 July 2023

View article titled, miR-15/16 clusters restrict effector Treg cell differentiation and function

Includes: Supplementary data

Journal Articles

IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation

In Special Collection:

Cytokines Collection 2023

Lina Petersone, Chun Jing Wang, Natalie M. Edner, Astrid Fabri, Spyridoula-Angeliki Nikou, Claudia Hinze, Ellen M. Ross, Elisavet Ntavli, Yassin Elfaki, Frank Heuts, Vitalijs Ovcinnikovs, Andrea Rueda Gonzalez, Luke P. Houghton, Hannah M. Li, Yang Zhang, Kai-Michael Toellner, Lucy S.K. Walker

J Exp Med (2023) 220 (10): e20221653.

https://doi.org/10.1084/jem.20221653

Published: 19 July 2023

View article titled, IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation

Includes: Supplementary data

Journal Articles

The Z-nucleic acid sensor ZBP1 in health and disease

Jonathan Maelfait, Jan Rehwinkel

J Exp Med (2023) 220 (8): e20221156.

https://doi.org/10.1084/jem.20221156

Published: 14 July 2023

View article titled, The Z-nucleic acid sensor ZBP1 in health and disease

Journal Articles

Single-cell profiling reveals unique features of diabetogenic T cells in anti-PD-1-induced type 1 diabetes mice

Jenna L. Collier, Kristen E. Pauken, Catherine A.A. Lee, Dillon G. Patterson, Samuel C. Markson, Thomas S. Conway, Megan E. Fung, Joshua A. France, Kyla N. Mucciarone, Christine G. Lian, George F. Murphy, Arlene H. Sharpe

J Exp Med (2023) 220 (10): e20221920.

https://doi.org/10.1084/jem.20221920

Published: 11 July 2023

View article titled, Single-cell profiling reveals unique features of diabetogenic T cells in anti-PD-1-induced type 1 diabetes mice

Includes: Supplementary data

Journal Articles

Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus

Daniel A. Michelson, Chong Zuo, Michael Verzi, Christophe Benoist, Diane Mathis

J Exp Med (2023) 220 (10): e20230461.

https://doi.org/10.1084/jem.20230461

Published: 03 July 2023

View article titled, Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus

Includes: Supplementary data

Journal Articles

Distinct inflammatory Th17 subsets emerge in autoimmunity and infection

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments

Ronald J. Bouch, Jing Zhang, Brandi C. Miller, Caroline J. Robbins, Timothy H. Mosher, Wencheng Li, Sergey A. Krupenko, Ravinder Nagpal, Jun Zhao, Richard S. Bloomfeld, Yong Lu, Mikhail A. Nikiforov, Qianqian Song, Zhiheng He

J Exp Med (2023) 220 (10): e20221911.

https://doi.org/10.1084/jem.20221911

Published: 27 June 2023

View article titled, Distinct inflammatory Th17 subsets emerge in autoimmunity and infection

Includes: Supplementary data

Journal Articles

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

In Special Collection:

Cytokines Collection 2023

Adrian Gervais, Francesca Rovida, Maria Antonietta Avanzini, Stefania Croce, Astrid Marchal, Shih-Ching Lin, Alessandro Ferrari, Christian W. Thorball, Orianne Constant, Tom Le Voyer, Quentin Philippot, Jérémie Rosain, Micol Angelini, Malena Pérez Lorenzo, Lucy Bizien, Cristian Achille, Francesca Trespidi, Elisa Burdino, Irene Cassaniti, Daniele Lilleri, Chiara Fornara, José Camilla Sammartino, Danilo Cereda, Chiara Marrocu, Antonio Piralla, Chiara Valsecchi, Stefano Ricagno, Paola Cogo, Olaf Neth, Inés Marín-Cruz, Monia Pacenti, Alessandro Sinigaglia, Marta Trevisan, Andrea Volpe, Antonio Marzollo, Francesca Conti, Tiziana Lazzarotto, Andrea Pession, Pierluigi Viale, Jacques Fellay, Stefano Ghirardello, Mélodie Aubart, Valeria Ghisetti, Alessandro Aiuti, Emmanuelle Jouanguy, Paul Bastard, Elena Percivalle, Fausto Baldanti, Anne Puel, Margaret R. MacDonald, Charles M. Rice, Giada Rossini, Kristy O. Murray, Yannick Simonin, Anna Nagy, Luisa Barzon, Laurent Abel, Michael S. Diamond, Aurélie Cobat, Shen-Ying Zhang, Jean-Laurent Casanova, Alessandro Borghesi

J Exp Med (2023) 220 (9): e20230661.

https://doi.org/10.1084/jem.20230661

Published: 22 June 2023

View article titled, Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

Journal Articles

Identification of an anergic B_ND cell–derived activated B cell population (B_ND2) in young-onset type 1 diabetes patients

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments , B cells, Infectious Diseases, and Autoimmunity , JEM Clinical Immunology Collection 2023

Zachary C. Stensland, Christopher A. Magera, Hali Broncucia, Brittany D. Gomez, Nasha M. Rios-Guzman, Kristen L. Wells, Catherine A. Nicholas, Marynette Rihanek, Maya J. Hunter, Kevin P. Toole, Peter A. Gottlieb, Mia J. Smith

J Exp Med (2023) 220 (8): e20221604.

https://doi.org/10.1084/jem.20221604

Published: 15 May 2023

View article titled, Identification of an anergic BND cell–derived activated B cell population (BND2) in young-onset type 1 diabetes patients

Includes: Supplementary data

Journal Articles

CTLA4 prohibits T cells from cross-dressing

Noémie Paillon, Claire Hivroz

J Exp Med (2023) 220 (7): e20230419.

https://doi.org/10.1084/jem.20230419

Published: 18 April 2023

View article titled, CTLA4 prohibits T cells from cross-dressing

Journal Articles

The stunning clodronate

Elvira Mass

J Exp Med (2023) 220 (6): e20230339.

https://doi.org/10.1084/jem.20230339

Published: 28 March 2023

View article titled, The stunning clodronate

Journal Articles

The interweaved signatures of common-gamma-chain cytokines across immunologic lineages

In Special Collection:

Innate Lymphoid Cells & Unconventional T Cells

Alev Baysoy, Kumba Seddu, Tamara Salloum, Caleb A. Dawson, Juliana J. Lee, Liang Yang, Shani Gal-oz, Hadas Ner-Gaon, Julie Tellier, Alberto Millan, Alexander Sasse, Brian Brown, Lewis L. Lanier, Tal Shay, Stephen Nutt, Daniel Dwyer, Christophe Benoist, The Immunological Genome Project Consortium

J Exp Med (2023) 220 (7): e20222052.

https://doi.org/10.1084/jem.20222052

Published: 28 March 2023

View article titled, The interweaved signatures of common-gamma-chain cytokines across immunologic lineages

Includes: Supplementary data

Journal Articles

Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms

In Special Collection:

JEM Clinical Immunology Collection 2023

Keenan A. Lacey, Lee Serpas, Sohei Makita, Yueyang Wang, Ali Rashidfarrokhi, Chetna Soni, Sandra Gonzalez, Andre Moreira, Victor J. Torres, Boris Reizis

J Exp Med (2023) 220 (6): e20221086.

https://doi.org/10.1084/jem.20221086

Published: 16 March 2023

View article titled, Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms

Journal Articles

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments , B cells, Infectious Diseases, and Autoimmunity , B Cell Biology in Health and Diseases

Kevin M. Nickerson, Shuchi Smita, Kenneth B. Hoehn, Anthony D. Marinov, Kayla B. Thomas, Justin T. Kos, Yi Yang, Sheldon I. Bastacky, Corey T. Watson, Steven H. Kleinstein, Mark J. Shlomchik

J Exp Med (2023) 220 (5): e20221346.

https://doi.org/10.1084/jem.20221346

Published: 24 February 2023

View article titled, Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

Includes: Supplementary data

Journal Articles

AP-1–independent NFAT signaling maintains follicular T cell function in infection and autoimmunity

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments

Abhinav Seth, Yoshiyuki Yokokura, Jin-Young Choi, Justin A. Shyer, Aurobind Vidyarthi, Joe Craft

J Exp Med (2023) 220 (5): e20211110.

https://doi.org/10.1084/jem.20211110

Published: 23 February 2023

View article titled, AP-1–independent NFAT signaling maintains follicular T cell function in infection and autoimmunity

Journal Articles

Regulatory T cells suppress CD4⁺ effector T cell activation by controlling protein synthesis

In Special Collection:

JEM Immunology Collection 2023 , Metabolism Signaling

Lomon So, Kazushige Obata-Ninomiya, Alex Hu, Virginia S. Muir, Ayako Takamori, Jing Song, Jane H. Buckner, Ram Savan, Steven F. Ziegler

J Exp Med (2023) 220 (3): e20221676.

https://doi.org/10.1084/jem.20221676

Published: 04 January 2023

View article titled, Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis

Includes: Supplementary data

Journal Articles

How decreasing T cell signaling unexpectedly results in autoimmunity

Jaeu Yi, Chyi-Song Hsieh

J Exp Med (2022) 220 (2): e20221886.

https://doi.org/10.1084/jem.20221886

Published: 15 December 2022

View article titled, How decreasing T cell signaling unexpectedly results in autoimmunity

Journal Articles

Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments

J Exp Med (2022) 220 (2): e20220386.

https://doi.org/10.1084/jem.20220386

Published: 01 December 2022

View article titled, Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease

Includes: Supplementary data

NARROW

TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance

Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice

Thymic mimicry: The art of imitation

miR-15/16 clusters restrict effector Treg cell differentiation and function

IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation

The Z-nucleic acid sensor ZBP1 in health and disease

Single-cell profiling reveals unique features of diabetogenic T cells in anti-PD-1-induced type 1 diabetes mice

Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus

Distinct inflammatory Th17 subsets emerge in autoimmunity and infection

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

Identification of an anergic B_ND cell–derived activated B cell population (B_ND2) in young-onset type 1 diabetes patients

CTLA4 prohibits T cells from cross-dressing

The stunning clodronate

The interweaved signatures of common-gamma-chain cytokines across immunologic lineages

Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

AP-1–independent NFAT signaling maintains follicular T cell function in infection and autoimmunity

Regulatory T cells suppress CD4⁺ effector T cell activation by controlling protein synthesis

How decreasing T cell signaling unexpectedly results in autoimmunity

Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease

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