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Gut microbiota biofilms: From regulatory mechanisms to therapeutic targets

Andre G. Buret, Thibault Allain

J Exp Med (2023) 220 (3): e20221743.

DOI: https://doi.org/10.1084/jem.20221743

Published: 23 January 2023

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Journal Articles

Microbiome influencers of checkpoint blockade–associated toxicity

In Special Collection:

Journal-Based CME Activities with Journal of Experimental Medicine (JEM)

Yinghong Wang, Robert R. Jenq, Jennifer A. Wargo, Stephanie S. Watowich

J Exp Med (2023) 220 (3): e20220948.

DOI: https://doi.org/10.1084/jem.20220948

Published: 09 January 2023

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Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses

In Special Collection:

Immunology Update Winter 2023

Suzanne H. Hodge, Maria Z. Krauss, Irem Kaymak, James I. King, Andrew J.M. Howden, Gordana Panic, Richard K. Grencis, Jonathan R. Swann, Linda V. Sinclair, Matthew R. Hepworth

J Exp Med (2022) 220 (3): e20221073.

DOI: https://doi.org/10.1084/jem.20221073

Published: 26 December 2022

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Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells

In Special Collection:

Immunology Update Winter 2023

Katherine A. Kaiser, Lucas F. Loffredo, Kenia de los Santos-Alexis, Olivia R. Ringham, Nicholas Arpaia

J Exp Med (2022) 220 (3): e20221462.

DOI: https://doi.org/10.1084/jem.20221462

Published: 19 December 2022

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Includes: Supplementary data

Journal Articles

cDC1-derived IL-27 regulates small intestinal CD4⁺ T cell homeostasis in mice

In Special Collection:

Immunology Update Winter 2023

Fatemeh Ahmadi, Fredrik Junghus, Christian Ashworth, Amanda Lappalainen, Urs Mörbe, Knut Kotarsky, William W. Agace

J Exp Med (2022) 220 (3): e20221090.

DOI: https://doi.org/10.1084/jem.20221090

Published: 14 December 2022

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Journal Articles

PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells

In Special Collection:

Immunology Update Winter 2023

Sarah C. Edwards, Ann Hedley, Wilma H.M. Hoevenaar, Robert Wiesheu, Teresa Glauner, Anna Kilbey, Robin Shaw, Katerina Boufea, Nizar Batada, Shinya Hatano, Yasunobu Yoshikai, Karen Blyth, Crispin Miller, Kristina Kirschner, Seth B. Coffelt

J Exp Med (2022) 220 (2): e20211431.

DOI: https://doi.org/10.1084/jem.20211431

Published: 07 December 2022

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Includes: Supplementary data

Journal Articles

Lectin recruits pathogenic bugs

Charles R. Schutt, Sho Yamasaki

J Exp Med (2022) 220 (1): e20221732.

DOI: https://doi.org/10.1084/jem.20221732

Published: 22 November 2022

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Journal Articles

Intelectin-1 binds and alters the localization of the mucus barrier–modifying bacterium Akkermansia muciniphila

J Exp Med (2022) 220 (1): e20211938.

DOI: https://doi.org/10.1084/jem.20211938

Published: 22 November 2022

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Includes: Supplementary data

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Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

In Special Collection:

Journal-Based CME Activities with Journal of Experimental Medicine (JEM) , Immunology Update Winter 2023

J Exp Med (2022) 220 (2): e20221333.

DOI: https://doi.org/10.1084/jem.20221333

Published: 11 November 2022

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Includes: Supplementary data

Journal Articles

Metabolic features of innate lymphoid cells

Huiyang Yu, Nicolas Jacquelot, Gabrielle T. Belz

J Exp Med (2022) 219 (11): e20221140.

DOI: https://doi.org/10.1084/jem.20221140

Published: 27 October 2022

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Journal Articles

Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice

Catalina Cosovanu, Philipp Resch, Stefan Jordan, Andrea Lehmann, Markus Ralser, Vadim Farztdinov, Joachim Spranger, Michael Mülleder, Sebastian Brachs, Christian Neumann

J Exp Med (2022) 219 (12): e20220233.

DOI: https://doi.org/10.1084/jem.20220233

Published: 19 September 2022

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Includes: Supplementary data

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The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium

Monica T. Jimenez, Megan L. Clark, Jasmine M. Wright, Michaël F. Michieletto, Suying Liu, Isabel Erickson, Lenka Dohnalova, Giulia T. Uhr, John Tello-Cajiao, Leonel Joannas, Adam Williams, Nicola Gagliani, Meenakshi Bewtra, Vesselin T. Tomov, Christoph A. Thaiss, Jorge Henao-Mejia

J Exp Med (2022) 219 (12): e20212278.

DOI: https://doi.org/10.1084/jem.20212278

Published: 08 September 2022

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Includes: Supplementary data

Journal Articles

Helminths revive to survive

John R. Grainger, Rufus H. Daw

J Exp Med e20221183.

DOI: https://doi.org/10.1084/jem.20221183

Published: 16 August 2022

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Journal Articles

Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules

Xuqiu Lei, Natalia Ketelut-Carneiro, Liraz Shmuel-Galia, Weili Xu, Ruth Wilson, Tim Vierbuchen, Yongzhi Chen, Andrea Reboldi, Joonsoo Kang, Karen L. Edelblum, Doyle Ward, Katherine A. Fitzgerald

J Exp Med (2022) 219 (8): e20212563.

DOI: https://doi.org/10.1084/jem.20212563

Published: 06 July 2022

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Includes: Supplementary data

Journal Articles

Fueling the fire in the gut

Chia-Hao Lin, Li-Fan Lu

J Exp Med (2022) 219 (7): e20220723.

DOI: https://doi.org/10.1084/jem.20220723

Published: 27 May 2022

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Journal Articles

Lysophosphatidylserines derived from microbiota in Crohn’s disease elicit pathological Th1 response

In Special Collection:

JEM Clinical Immunology Collection 2022 , Cytokines Collection 2022

Yuriko Otake-Kasamoto, Hisako Kayama, Toshihiro Kishikawa, Shinichiro Shinzaki, Taku Tashiro, Takahiro Amano, Mizuki Tani, Takeo Yoshihara, Bo Li, Haruka Tani, Li Liu, Akio Hayashi, Daisuke Okuzaki, Daisuke Motooka, Shota Nakamura, Yukinori Okada, Hideki Iijima, Kiyoshi Takeda, Tetsuo Takehara

J Exp Med (2022) 219 (7): e20211291.

DOI: https://doi.org/10.1084/jem.20211291

Published: 24 May 2022

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Includes: Supplementary data

Journal Articles

Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity

Jihye Han, Qingqing Wan, Goo-Young Seo, Kenneth Kim, Sarah el Baghdady, Jee H. Lee, Mitchell Kronenberg, Yun-Cai Liu

J Exp Med (2022) 219 (6): e20211985.

DOI: https://doi.org/10.1084/jem.20211985

Published: 09 May 2022

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Includes: Supplementary data

Journal Articles

miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease

In Special Collection:

JEM Mucosal Immunology 2022

Carlos Perez-Sanchez, Ariana Barbera Betancourt, Paul A. Lyons, Zinan Zhang, Chenqu Suo, James C. Lee, Eoin F. McKinney, Louise K. Modis, Christian Ellson, Kenneth G.C. Smith

J Exp Med (2022) 219 (5): e20211366.

DOI: https://doi.org/10.1084/jem.20211366

Published: 01 April 2022

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Includes: Supplementary data

Journal Articles

Adapting to their new home: Eosinophils remodel the gut architecture

Isabelle Catherine Arnold

J Exp Med (2022) 219 (4): e20220146.

DOI: https://doi.org/10.1084/jem.20220146

Published: 22 March 2022

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Journal Articles

Allo-reactive tissue-resident T cells causing damage: An inside job

René A.W. van Lier, Pleun Hombrink

J Exp Med (2022) 219 (4): e20220121.

DOI: https://doi.org/10.1084/jem.20220121

Published: 14 March 2022

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2 3 4 5

NARROW

Gut microbiota biofilms: From regulatory mechanisms to therapeutic targets

Microbiome influencers of checkpoint blockade–associated toxicity

Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses

Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells

cDC1-derived IL-27 regulates small intestinal CD4⁺ T cell homeostasis in mice

PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells

Lectin recruits pathogenic bugs

Intelectin-1 binds and alters the localization of the mucus barrier–modifying bacterium Akkermansia muciniphila

Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Metabolic features of innate lymphoid cells

Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice

The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium

Helminths revive to survive

Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules

Fueling the fire in the gut

Lysophosphatidylserines derived from microbiota in Crohn’s disease elicit pathological Th1 response

Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity

miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease

Adapting to their new home: Eosinophils remodel the gut architecture

Allo-reactive tissue-resident T cells causing damage: An inside job

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