Page 1 | Search Results | Journal of Experimental Medicine

1-20 of 109

Sort by

Sort Order Select

Journal Articles

ARL6IP1 gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spastic paraplegia model

Jung Hwa Lim, Hyun Mi Kang, Dae Hun Kim, Bohyeon Jeong, Da Yong Lee, Jae-Ran Lee, Jeong Yeob Baek, Hyun-Soo Cho, Mi-Young Son, Dae Soo Kim, Nam-Soon Kim, Cho-Rok Jung

J Exp Med (2023) 221 (1): e20230367.

https://doi.org/10.1084/jem.20230367

Published: 07 November 2023

View article titled, <em>ARL6IP1</em> gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spastic paraplegia model

Includes: Supplementary data

Journal Articles

A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation

In Special Collection:

Neuroscience Collection 2023

J Exp Med (2023) 220 (11): e20222105.

https://doi.org/10.1084/jem.20222105

Published: 29 August 2023

View article titled, A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation

Includes: Supplementary data

Journal Articles

CD8⁺ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

In Special Collection:

Neuroscience Collection 2023

Pearl A. Sutter, Antoine Ménoret, Evan R. Jellison, Alexandra M. Nicaise, Allison M. Bradbury, Anthony T. Vella, Ernesto R. Bongarzone, Stephen J. Crocker

J Exp Med (2023) 220 (9): e20221862.

https://doi.org/10.1084/jem.20221862

Published: 13 June 2023

View article titled, CD8<sup>+</sup> T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

Includes: Supplementary data

Journal Articles

Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage

In Special Collection:

Neuroscience Collection 2023 , Neuroimmunology and Neurodegeneration 2023

Justin Rustenhoven, Georgios Pavlou, Steffen E. Storck, Taitea Dykstra, Siling Du, Zhengpeng Wan, Daniel Quintero, Joshua P. Scallan, Igor Smirnov, Roger D. Kamm, Jonathan Kipnis

J Exp Med (2023) 220 (7): e20221929.

https://doi.org/10.1084/jem.20221929

Published: 07 April 2023

View article titled, Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage

Journal Articles

Engineering mighty microglia

Adeline E. Walsh, John R. Lukens

J Exp Med (2023) 220 (3): e20222070.

https://doi.org/10.1084/jem.20222070

Published: 17 January 2023

View article titled, Engineering mighty microglia

Journal Articles

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

In Special Collection:

JEM Clinical Immunology Collection 2023 , Neuroimmunology and Neurodegeneration 2023

J Exp Med (2022) 220 (3): e20220857.

https://doi.org/10.1084/jem.20220857

Published: 30 December 2022

View article titled, Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

Includes: Supplementary data

Journal Articles

Targeting neuroinflammation in neuropathic pain and opioid use

In Special Collection:

Neuroscience Collection 2023 , Neuroimmunology and Neurodegeneration 2023

Daniela Salvemini, Timothy M. Doyle

J Exp Med (2022) 220 (2): e20221244.

https://doi.org/10.1084/jem.20221244

Published: 23 December 2022

View article titled, Targeting neuroinflammation in neuropathic pain and opioid use

Journal Articles

Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

In Special Collection:

Neuroimmunology and Neurodegeneration 2023

Rafael T. Han, Ilia D. Vainchtein, Johannes C.M. Schlachetzki, Frances S. Cho, Leah C. Dorman, Eunji Ahn, Dong Kyu Kim, Jerika J. Barron, Hiromi Nakao-Inoue, Ari B. Molofsky, Christopher K. Glass, Jeanne T. Paz, Anna V. Molofsky

J Exp Med (2022) 220 (2): e20220605.

https://doi.org/10.1084/jem.20220605

Published: 15 December 2022

View article titled, Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

Includes: Supplementary data

Journal Articles

Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma

In Special Collection:

Neuroscience Collection 2023

Trishna Shah, Sue E. Leurgans, Rashi I. Mehta, Jingyun Yang, Chad A. Galloway, Karen L. de Mesy Bentley, Julie A. Schneider, Rupal I. Mehta

J Exp Med (2022) 220 (2): e20220618.

https://doi.org/10.1084/jem.20220618

Published: 05 December 2022

View article titled, Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma

Includes: Supplementary data

Journal Articles

The X factor in neurodegeneration

In Special Collection:

Autoimmunity: From Novel Mechanisms to Treatments , Neuroimmunology and Neurodegeneration 2023

Rhonda Voskuhl, Yuichiro Itoh

J Exp Med (2022) 219 (12): e20211488.

https://doi.org/10.1084/jem.20211488

Published: 04 November 2022

View article titled, The X factor in neurodegeneration

Journal Articles

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

In Special Collection:

Neuroscience Collection 2023 , Neuroimmunology and Neurodegeneration 2023

Nimansha Jain, Caroline A. Lewis, Jason D. Ulrich, David M. Holtzman

J Exp Med (2022) 220 (1): e20220654.

https://doi.org/10.1084/jem.20220654

Published: 11 October 2022

View article titled, Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

Includes: Supplementary data

Journal Articles

Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

In Special Collection:

Tolerance and Autoimmunity

J Exp Med (2022) 219 (11): e20220650.

https://doi.org/10.1084/jem.20220650

Published: 01 September 2022

View article titled, Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

Includes: Supplementary data

Journal Articles

Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis

In Special Collection:

Immunology Update Winter 2023 , Neuroscience Collection 2022 , Tolerance and Autoimmunity

Shen-zhao Lu, Yue Wu, Yong-shun Guo, Pei-zhou Liang, Shu Yin, Yan-qing Yin, Xiu-li Zhang, Yan-Fang Liu, Hong-yan Wang, Yi-chuan Xiao, Xin-miao Liang, Jia-wei Zhou

J Exp Med (2022) 219 (9): e20210998.

https://doi.org/10.1084/jem.20210998

Published: 25 July 2022

View article titled, Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis

Includes: Supplementary data

Journal Articles

IL-24 intrinsically regulates Th17 cell pathogenicity in mice

In Special Collection:

Cytokines Collection 2022

Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl, Helena Domínguez Moreno, Tereza Chadimová, Gildas Lepennetier, Tanja Kuhlmann, Rupert Öllinger, Thomas Engleitner, Roland Rad, Thomas Korn

J Exp Med (2022) 219 (8): e20212443.

https://doi.org/10.1084/jem.20212443

Published: 12 July 2022

View article titled, IL-24 intrinsically regulates Th17 cell pathogenicity in mice

Includes: Supplementary data

Journal Articles

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Xuefang Pan, Mahsa Taherzadeh, Poulomee Bose, Rachel Heon-Roberts, Annie L.A. Nguyen, TianMeng Xu, Camila Pará, Yojiro Yamanaka, David A. Priestman, Frances M. Platt, Shaukat Khan, Nidhi Fnu, Shunji Tomatsu, Carlos R. Morales, Alexey V. Pshezhetsky

J Exp Med (2022) 219 (8): e20211860.

https://doi.org/10.1084/jem.20211860

Published: 15 June 2022

View article titled, Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Includes: Supplementary data

Journal Articles

Interleukin-4 receptor signaling modulates neuronal network activity

In Special Collection:

Cytokines Collection 2022

Nicholas Hanuscheck, Carine Thalman, Micaela Domingues, Samantha Schmaul, Muthuraman Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, Gianvito Martino, Tanja Kuhlmann, Katarzyna Bozek, Tim van Beers, Stefan Bittner, Jakob von Engelhardt, Johannes Vogt, Christina Francisca Vogelaar, Frauke Zipp

J Exp Med (2022) 219 (6): e20211887.

https://doi.org/10.1084/jem.20211887

Published: 19 May 2022

View article titled, Interleukin-4 receptor signaling modulates neuronal network activity

Includes: Supplementary data

Journal Articles

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

In Special Collection:

Innate Immunity: From Basic Biology to Human Disease , Neuroscience Collection 2022

J Exp Med (2022) 219 (4): e20211121.

https://doi.org/10.1084/jem.20211121

Published: 09 March 2022

View article titled, DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

Includes: Supplementary data

Journal Articles

Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

J Exp Med (2022) 219 (3): e20211071.

https://doi.org/10.1084/jem.20211071

Published: 24 February 2022

View article titled, Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

Includes: Supplementary data

Journal Articles

The gut–meningeal immune axis: Priming brain defense against the most likely invaders

In Special Collection:

JEM Mucosal Immunology 2022 , Neuroscience Collection 2022 , Neuroimmunology and Neurodegeneration

Rafael Di Marco Barros, Zachary Fitzpatrick, Menna R. Clatworthy

J Exp Med (2022) 219 (3): e20211520.

https://doi.org/10.1084/jem.20211520

Published: 23 February 2022

View article titled, The gut–meningeal immune axis: Priming brain defense against the most likely invaders

Journal Articles

Neural control of immune cell trafficking

In Special Collection:

Neuroscience Collection 2022 , Neuroimmunology and Neurodegeneration

Scott N. Mueller

J Exp Med (2022) 219 (3): e20211604.

https://doi.org/10.1084/jem.20211604

Published: 23 February 2022

View article titled, Neural control of immune cell trafficking

NARROW

ARL6IP1 gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spastic paraplegia model

A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation

CD8⁺ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage

Engineering mighty microglia

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

Targeting neuroinflammation in neuropathic pain and opioid use

Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma

The X factor in neurodegeneration

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis

IL-24 intrinsically regulates Th17 cell pathogenicity in mice

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Interleukin-4 receptor signaling modulates neuronal network activity

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

The gut–meningeal immune axis: Priming brain defense against the most likely invaders

Neural control of immune cell trafficking

Email alerts

Email alerts

This Feature Is Available To Subscribers Only