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Journal Articles

STING trafficking as a new dimension of immune signaling

Devon Jeltema, Kennady Abbott, Nan Yan

J Exp Med (2023) 220 (3): e20220990.

DOI: https://doi.org/10.1084/jem.20220990

Published: 27 January 2023

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Journal Articles

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

J Exp Med (2022) 220 (3): e20220857.

DOI: https://doi.org/10.1084/jem.20220857

Published: 30 December 2022

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Includes: Supplementary data

Journal Articles

Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury

Valérie Van Steenbergen, Laura Burattini, Michelle Trumpp, Julie Fourneau, Almir Aljović, Maryam Chahin, Hanseul Oh, Marta D’Ambra, Florence M. Bareyre

J Exp Med (2022) 220 (3): e20220615.

DOI: https://doi.org/10.1084/jem.20220615

Published: 26 December 2022

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Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

Rafael T. Han, Ilia D. Vainchtein, Johannes C.M. Schlachetzki, Frances S. Cho, Leah C. Dorman, Eunji Ahn, Dong Kyu Kim, Jerika J. Barron, Hiromi Nakao-Inoue, Ari B. Molofsky, Christopher K. Glass, Jeanne T. Paz, Anna V. Molofsky

J Exp Med (2022) 220 (2): e20220605.

DOI: https://doi.org/10.1084/jem.20220605

Published: 15 December 2022

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Includes: Supplementary data

Journal Articles

CSF-to-dura gateways

Jean-Leon Thomas, Helene Benveniste

J Exp Med (2022) 220 (2): e20221719.

DOI: https://doi.org/10.1084/jem.20221719

Published: 06 December 2022

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Journal Articles

Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma

Trishna Shah, Sue E. Leurgans, Rashi I. Mehta, Jingyun Yang, Chad A. Galloway, Karen L. de Mesy Bentley, Julie A. Schneider, Rupal I. Mehta

J Exp Med (2022) 220 (2): e20220618.

DOI: https://doi.org/10.1084/jem.20220618

Published: 05 December 2022

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Includes: Supplementary data

Journal Articles

The X factor in neurodegeneration

Rhonda Voskuhl, Yuichiro Itoh

J Exp Med (2022) 219 (12): e20211488.

DOI: https://doi.org/10.1084/jem.20211488

Published: 04 November 2022

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Journal Articles

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

Nimansha Jain, Caroline A. Lewis, Jason D. Ulrich, David M. Holtzman

J Exp Med (2022) 220 (1): e20220654.

DOI: https://doi.org/10.1084/jem.20220654

Published: 11 October 2022

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Includes: Supplementary data

Journal Articles

Sleep exerts lasting effects on hematopoietic stem cell function and diversity

In Special Collection:

Journal-Based CME Activities with Journal of Experimental Medicine (JEM) , Hematology 2022 , 2022: The Year in Experimental Medicine

J Exp Med (2022) 219 (11): e20220081.

DOI: https://doi.org/10.1084/jem.20220081

Published: 21 September 2022

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Includes: Supplementary data

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Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia

J Exp Med (2022) 219 (12): e20212479.

DOI: https://doi.org/10.1084/jem.20212479

Published: 15 September 2022

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Includes: Supplementary data

Journal Articles

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice

Giuseppe Barisano, Kassandra Kisler, Brent Wilkinson, Angeliki Maria Nikolakopoulou, Abhay P. Sagare, Yaoming Wang, William Gilliam, Mikko T. Huuskonen, Shu-Ting Hung, Justin K. Ichida, Fan Gao, Marcelo P. Coba, Berislav V. Zlokovic

J Exp Med (2022) 219 (11): e20221137.

DOI: https://doi.org/10.1084/jem.20221137

Published: 30 August 2022

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Includes: Supplementary data

Journal Articles

Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons

In Special Collection:

Neuroscience Collection 2022

Rachana Mishra, Trongha Phan, Pavan Kumar, Zachery Morrissey, Muskan Gupta, Carolyn Hollands, Aashutosh Shetti, Kyra Lauren Lopez, Mark Maienschein-Cline, Hoonkyo Suh, Rene Hen, Orly Lazarov

J Exp Med (2022) 219 (9): e20220391.

DOI: https://doi.org/10.1084/jem.20220391

Published: 19 August 2022

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Includes: Supplementary data

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Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder

In Special Collection:

Neuroscience Collection 2022 , Tolerance and Autoimmunity

J Exp Med (2022) 219 (9): e20220498.

DOI: https://doi.org/10.1084/jem.20220498

Published: 10 August 2022

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Includes: Supplementary data

Journal Articles

Delineating a serotonin 1B receptor circuit for appetite suppression in mice

In Special Collection:

Neuroscience Collection 2022

Li Li, Steven C. Wyler, Luis A. León-Mercado, Baijie Xu, Youjin Oh, Swati, Xiameng Chen, Rong Wan, Amanda G. Arnold, Lin Jia, Guanlin Wang, Katherine Nautiyal, René Hen, Jong-Woo Sohn, Chen Liu

J Exp Med (2022) 219 (8): e20212307.

DOI: https://doi.org/10.1084/jem.20212307

Published: 07 July 2022

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Journal Articles

Charting the meningeal lymphatic network

Sandro Da Mesquita

J Exp Med (2022) 219 (8): e20220891.

DOI: https://doi.org/10.1084/jem.20220891

Published: 05 July 2022

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Journal Articles

Conserved meningeal lymphatic drainage circuits in mice and humans

In Special Collection:

Lymphatic Vessels in Health and Disease 2022 , Neuroscience Collection 2022

Laurent Jacob, Jose de Brito Neto, Stephanie Lenck, Celine Corcy, Farhat Benbelkacem, Luiz Henrique Geraldo, Yunling Xu, Jean-Mickael Thomas, Marie-Renee El Kamouh, Myriam Spajer, Marie-Claude Potier, Stephane Haik, Michel Kalamarides, Bruno Stankoff, Stephane Lehericy, Anne Eichmann, Jean-Leon Thomas

J Exp Med (2022) 219 (8): e20220035.

DOI: https://doi.org/10.1084/jem.20220035

Published: 01 July 2022

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Journal Articles

The dense-core plaques of Alzheimer’s disease are granulomas

In Special Collection:

Neuroscience Collection 2022

Greg Lemke, Youtong Huang

J Exp Med (2022) 219 (8): e20212477.

DOI: https://doi.org/10.1084/jem.20212477

Published: 22 June 2022

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Journal Articles

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Xuefang Pan, Mahsa Taherzadeh, Poulomee Bose, Rachel Heon-Roberts, Annie L.A. Nguyen, TianMeng Xu, Camila Pará, Yojiro Yamanaka, David A. Priestman, Frances M. Platt, Shaukat Khan, Nidhi Fnu, Shunji Tomatsu, Carlos R. Morales, Alexey V. Pshezhetsky

J Exp Med (2022) 219 (8): e20211860.

DOI: https://doi.org/10.1084/jem.20211860

Published: 15 June 2022

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Includes: Supplementary data

Journal Articles

Interleukin-4 receptor signaling modulates neuronal network activity

In Special Collection:

Cytokines Collection 2022

Nicholas Hanuscheck, Carine Thalman, Micaela Domingues, Samantha Schmaul, Muthuraman Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, Gianvito Martino, Tanja Kuhlmann, Katarzyna Bozek, Tim van Beers, Stefan Bittner, Jakob von Engelhardt, Johannes Vogt, Christina Francisca Vogelaar, Frauke Zipp

J Exp Med (2022) 219 (6): e20211887.

DOI: https://doi.org/10.1084/jem.20211887

Published: 19 May 2022

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Includes: Supplementary data

Journal Articles

ATP spreads inflammation to other limbs through crosstalk between sensory neurons and interneurons

In Special Collection:

Neuroimmunology and Neurodegeneration , 2022: The Year in Experimental Medicine

Rie Hasebe, Kaoru Murakami, Masaya Harada, Nada Halaka, Hiroshi Nakagawa, Fuminori Kawano, Yoshinobu Ohira, Tadafumi Kawamoto, Fiona E. Yull, Timothy S. Blackwell, Junko Nio-Kobayashi, Toshihiko Iwanaga, Masahiko Watanabe, Nobuhiro Watanabe, Harumi Hotta, Toshihide Yamashita, Daisuke Kamimura, Yuki Tanaka, Masaaki Murakami

J Exp Med (2022) 219 (6): e20212019.

DOI: https://doi.org/10.1084/jem.20212019

Published: 17 May 2022

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2 3 4 5

NARROW

STING trafficking as a new dimension of immune signaling

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury

Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

CSF-to-dura gateways

Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma

The X factor in neurodegeneration

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

Sleep exerts lasting effects on hematopoietic stem cell function and diversity

Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice

Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons

Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder

Delineating a serotonin 1B receptor circuit for appetite suppression in mice

Charting the meningeal lymphatic network

Conserved meningeal lymphatic drainage circuits in mice and humans

The dense-core plaques of Alzheimer’s disease are granulomas

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT

Interleukin-4 receptor signaling modulates neuronal network activity

ATP spreads inflammation to other limbs through crosstalk between sensory neurons and interneurons

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