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Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

In Special Collection:

Biophysics 2022 , Neuroscience Collection 2021

Peter Proks, Marcus Schewe, Linus J. Conrad, Shanlin Rao, Kristin Rathje, Karin E.J. Rödström, Elisabeth P. Carpenter, Thomas Baukrowitz, Stephen J. Tucker

J Gen Physiol (2021) 153 (8): e202012812.

DOI: https://doi.org/10.1085/jgp.202012812

Published: 25 May 2021

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Includes: Supplementary data

Journal Articles

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A K_ATP channels: A mechanistic study

Peter Proks, Heidi de Wet, Frances M. Ashcroft

J Gen Physiol (2014) 144 (5): 469–486.

DOI: https://doi.org/10.1085/jgp.201411222

Published: 27 October 2014

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Includes: Supplementary data

Journal Articles

Activation of the K_ATP channel by Mg-nucleotide interaction with SUR1

Peter Proks, Heidi de Wet, Frances M. Ashcroft

J Gen Physiol (2010) 136 (4): 389–405.

DOI: https://doi.org/10.1085/jgp.201010475

Published: 27 September 2010

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Journal Articles

How ATP Inhibits the Open K_ATP Channel

Tim J. Craig, Frances M. Ashcroft, Peter Proks

J Gen Physiol (2008) 132 (1): 131–144.

DOI: https://doi.org/10.1085/jgp.200709874

Published: 30 June 2008

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Includes: Supplementary data

Journal Articles

Mutations within the P-Loop of Kir6.2 Modulate the Intraburst Kinetics of the Atp-Sensitive Potassium Channel

Peter Proks, Charlotte E. Capener, Phillippa Jones, Frances M. Ashcroft

J Gen Physiol (2001) 118 (4): 341–353.

DOI: https://doi.org/10.1085/jgp.118.4.341

Published: 18 September 2001

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Journal Articles

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

Stefan Trapp, Peter Proks, Stephen J. Tucker, Frances M. Ashcroft

J Gen Physiol (1998) 112 (3): 333–349.

DOI: https://doi.org/10.1085/jgp.112.3.333

Published: 01 September 1998

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NARROW

Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A K_ATP channels: A mechanistic study

Activation of the K_ATP channel by Mg-nucleotide interaction with SUR1

How ATP Inhibits the Open K_ATP Channel

Mutations within the P-Loop of Kir6.2 Modulate the Intraburst Kinetics of the Atp-Sensitive Potassium Channel

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

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Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: A mechanistic study

Activation of the KATP channel by Mg-nucleotide interaction with SUR1

How ATP Inhibits the Open KATP Channel

Mutations within the P-Loop of Kir6.2 Modulate the Intraburst Kinetics of the Atp-Sensitive Potassium Channel

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

Email alerts

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Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A K_ATP channels: A mechanistic study

Activation of the K_ATP channel by Mg-nucleotide interaction with SUR1

How ATP Inhibits the Open K_ATP Channel