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Stephen J. Tucker
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Journal Articles

When is a hydrophobic gate not a hydrophobic gate?

David Seiferth, Philip C. Biggin, Stephen J. Tucker
Journal: Journal of General Physiology
J Gen Physiol (2022) 154 (11): e202213210.
DOI: https://doi.org/10.1085/jgp.202213210
Published: 26 October 2022
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Journal Articles

Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

In Special Collection:
Biophysics 2022 , Neuroscience Collection 2021
Peter Proks, Marcus Schewe, Linus J. Conrad, Shanlin Rao, Kristin Rathje, Karin E.J. Rödström, Elisabeth P. Carpenter, Thomas Baukrowitz, Stephen J. Tucker
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (8): e202012812.
DOI: https://doi.org/10.1085/jgp.202012812
Published: 25 May 2021
View article titled, Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate
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Includes: Supplementary data
Journal Articles

Dynamic role of the tether helix in PIP2-dependent gating of a G protein–gated potassium channel

Emre Lacin, Prafulla Aryal, Ian W. Glaaser, Karthik Bodhinathan, Eric Tsai, Nidaa Marsh, Stephen J. Tucker, Mark S.P. Sansom, Paul A. Slesinger
Journal: Journal of General Physiology
J Gen Physiol (2017) 149 (8): 799–811.
DOI: https://doi.org/10.1085/jgp.201711801
Published: 18 July 2017
View article titled, Dynamic role of the tether helix in PIP<sub>2</sub>-dependent gating of a G protein–gated potassium channel
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Includes: Supplementary data
Journal Articles

Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states

Conor McClenaghan, Marcus Schewe, Prafulla Aryal, Elisabeth P. Carpenter, Thomas Baukrowitz, Stephen J. Tucker
Journal: Journal of General Physiology
J Gen Physiol (2016) 147 (6): 497–505.
DOI: https://doi.org/10.1085/jgp.201611601
Published: 30 May 2016
View article titled, Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states
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Journal Articles

How Highly Charged Anionic Lipids Bind and Regulate Ion Channels

Stephen J. Tucker, Thomas Baukrowitz
Journal: Journal of General Physiology
J Gen Physiol (2008) 131 (5): 431–438.
DOI: https://doi.org/10.1085/jgp.200709936
Published: 14 April 2008
View article titled, How Highly Charged Anionic Lipids Bind and Regulate Ion Channels
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Journal Articles

Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification

Stefan Trapp, Stephen J. Tucker, Frances M. Ashcroft
Journal: Journal of General Physiology
J Gen Physiol (1998) 112 (3): 325–332.
DOI: https://doi.org/10.1085/jgp.112.3.325
Published: 01 September 1998
View article titled, Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification
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Journal Articles

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

Stefan Trapp, Peter Proks, Stephen J. Tucker, Frances M. Ashcroft
Journal: Journal of General Physiology
J Gen Physiol (1998) 112 (3): 333–349.
DOI: https://doi.org/10.1085/jgp.112.3.333
Published: 01 September 1998
View article titled, Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP
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