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Journal Articles

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

J Gen Physiol (2023) 155 (7): e202213268.

DOI: https://doi.org/10.1085/jgp.202213268

Published: 25 May 2023

View article titled, Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

Includes: Supplementary data

Journal Articles

Blockade of TRPV channels by intracellular spermine

Grigory Maksaev, Peng Yuan, Colin G. Nichols

J Gen Physiol (2023) 155 (5): e202213273.

DOI: https://doi.org/10.1085/jgp.202213273

Published: 13 March 2023

View article titled, Blockade of TRPV channels by intracellular spermine

Journal Articles

Real-time observation of functional specialization among phosphorylation sites in CFTR

Daniel T. Infield, Miranda E. Schene, Frederico S. Fazan, Grace D. Galles, Jason D. Galpin, Christopher A. Ahern

J Gen Physiol (2023) 155 (4): e202213216.

DOI: https://doi.org/10.1085/jgp.202213216

Published: 25 January 2023

View article titled, Real-time observation of functional specialization among phosphorylation sites in CFTR

Includes: Supplementary data

Journal Articles

Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development

Jamison L. Nourse, Vivian M. Leung, Hamid Abuwarda, Elizabeth L. Evans, Esmeralda Izquierdo-Ortiz, Alan T. Ly, Nguyen Truong, Samantha Smith, Harsh Bhavsar, Gabriella Bertaccini, Edwin S. Monuki, Mitradas M. Panicker, Medha M. Pathak

J Gen Physiol (2022) 154 (10): e202213084.

DOI: https://doi.org/10.1085/jgp.202213084

Published: 07 September 2022

View article titled, Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development

Includes: Supplementary data

Journal Articles

Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy

Maricela García-Castañeda, Antonio Michelucci, Nan Zhao, Sundeep Malik, Robert T. Dirksen

J Gen Physiol (2022) 154 (9): e202213081.

DOI: https://doi.org/10.1085/jgp.202213081

Published: 08 August 2022

View article titled, Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy

Includes: Supplementary data

Journal Articles

ORAI3 is dispensable for store-operated Ca²⁺ entry and immune responses by lymphocytes and macrophages

Liwei Wang, Lucile Noyer, Yin-Hu Wang, Anthony Y. Tao, Wenyi Li, Jingjie Zhu, Pedro Saavedra, Syed T. Hoda, Jun Yang, Stefan Feske

J Gen Physiol (2022) 154 (10): e202213104.

DOI: https://doi.org/10.1085/jgp.202213104

Published: 21 July 2022

View article titled, ORAI3 is dispensable for store-operated Ca<sup>2+</sup> entry and immune responses by lymphocytes and macrophages

Includes: Supplementary data

Journal Articles

Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P₂ synthesis

Lizbeth de la Cruz, Christopher Kushmerick, Jane M. Sullivan, Martin Kruse, Oscar Vivas

J Gen Physiol (2022) 154 (3): e202113001.

DOI: https://doi.org/10.1085/jgp.202113001

Published: 18 February 2022

View article titled, Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P<sub>2</sub> synthesis

Includes: Supplementary data

Journal Articles

The N2A region of titin has a unique structural configuration

In Special Collection:

Biophysics 2022

Chiara Stronczek, Stephan Lange, Belinda Bullard, Sebastian Wolniak, Emma Börgeson, Olga Mayans, Jennifer R. Fleming

J Gen Physiol (2021) 153 (7): e202012766.

DOI: https://doi.org/10.1085/jgp.202012766

Published: 09 April 2021

View article titled, The N2A region of titin has a unique structural configuration

Journal Articles

The role of molecular diffusion within dendritic spines in synaptic function

In Special Collection:

Neuroscience Collection 2021

Kazuki Obashi, Justin W. Taraska, Shigeo Okabe

J Gen Physiol (2021) 153 (4): e202012814.

DOI: https://doi.org/10.1085/jgp.202012814

Published: 15 March 2021

View article titled, The role of molecular diffusion within dendritic spines in synaptic function

Journal Articles

Molecular underpinning of intracellular pH regulation on TMEM16F

In Special Collection:

Biophysics 2022 , Protons and Membrane Function

Pengfei Liang, Huanghe Yang

J Gen Physiol (2020) 153 (2): e202012704.

DOI: https://doi.org/10.1085/jgp.202012704

Published: 21 December 2020

View article titled, Molecular underpinning of intracellular pH regulation on TMEM16F

Includes: Supplementary data

Journal Articles

The very low number of calcium-induced permeability transition pores in the single mitochondrion

In Special Collection:

Biophysics 2021

Maria A. Neginskaya, Jasiel O. Strubbe, Giuseppe F. Amodeo, Benjamin A. West, Shoshana Yakar, Jason N. Bazil, Evgeny V. Pavlov

J Gen Physiol (2020) 152 (10): e202012631.

DOI: https://doi.org/10.1085/jgp.202012631

Published: 17 August 2020

View article titled, The very low number of calcium-induced permeability transition pores in the single mitochondrion

Journal Articles

Roles for the SNAP25 linker domain in the fusion pore and a dynamic plasma membrane SNARE “acceptor” complex

Ronald W. Holz, Mary A. Bittner

J Gen Physiol (2020) 152 (9): e202012619.

DOI: https://doi.org/10.1085/jgp.202012619

Published: 28 July 2020

View article titled, Roles for the SNAP25 linker domain in the fusion pore and a dynamic plasma membrane SNARE “acceptor” complex

Journal Articles

Membrane conductances of mouse cone photoreceptors

Norianne T. Ingram, Alapakkam P. Sampath, Gordon L. Fain

J Gen Physiol (2020) 152 (3): e201912520.

DOI: https://doi.org/10.1085/jgp.201912520

Published: 27 January 2020

View article titled, Membrane conductances of mouse cone photoreceptors

Journal Articles

The central role of the tail in switching off 10S myosin II activity

Shixin Yang, Kyoung Hwan Lee, John L. Woodhead, Osamu Sato, Mitsuo Ikebe, Roger Craig

J Gen Physiol (2019) 151 (9): 1081–1093.

DOI: https://doi.org/10.1085/jgp.201912431

Published: 06 August 2019

View article titled, The central role of the tail in switching off 10S myosin II activity

Includes: Supplementary data

Journal Articles

A primer on resolving the nanoscale structure of the plasma membrane with light and electron microscopy

Justin W. Taraska

J Gen Physiol (2019) 151 (8): 974–985.

DOI: https://doi.org/10.1085/jgp.201812227

Published: 28 June 2019

View article titled, A primer on resolving the nanoscale structure of the plasma membrane with light and electron microscopy

Journal Articles

Evolution of our understanding of cell volume regulation by the pump-leak mechanism

Alan R. Kay, Mordecai P. Blaustein

J Gen Physiol (2019) 151 (4): 407–416.

DOI: https://doi.org/10.1085/jgp.201812274

Published: 19 February 2019

View article titled, Evolution of our understanding of cell volume regulation by the pump-leak mechanism

Journal Articles

Unraveling the mechanisms of calcium-dependent secretion

Arun Anantharam, Alex J.B. Kreutzberger

J Gen Physiol (2019) 151 (4): 417–434.

DOI: https://doi.org/10.1085/jgp.201812298

Published: 19 February 2019

View article titled, Unraveling the mechanisms of calcium-dependent secretion

Journal Articles

Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors

In Special Collection:

Excitatory Synapses , Molecular Basis of Disease and Therapy in the Nervous System

Amol V. Shivange, Philip M. Borden, Anand K. Muthusamy, Aaron L. Nichols, Kallol Bera, Huan Bao, Ishak Bishara, Janice Jeon, Matthew J. Mulcahy, Bruce Cohen, Saidhbhe L. O'Riordan, Charlene Kim, Dennis A. Dougherty, Edwin R. Chapman, Jonathan S. Marvin, Loren L. Looger, Henry A. Lester

J Gen Physiol (2019) 151 (6): 738–757.

DOI: https://doi.org/10.1085/jgp.201812201

Published: 04 February 2019

View article titled, Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors

Includes: Supplementary data

Journal Articles

Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion

Prabhodh S. Abbineni, Mary A. Bittner, Daniel Axelrod, Ronald W. Holz

J Gen Physiol (2018) 151 (2): 118–130.

DOI: https://doi.org/10.1085/jgp.201812182

Published: 30 November 2018

View article titled, Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion

Includes: Supplementary data

Journal Articles

Visualization of expanding fusion pores in secretory cells

Prabhodh S. Abbineni, Daniel Axelrod, Ronald W. Holz

J Gen Physiol (2018) 150 (12): 1640–1646.

DOI: https://doi.org/10.1085/jgp.201812186

Published: 23 November 2018

View article titled, Visualization of expanding fusion pores in secretory cells

NARROW

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

Blockade of TRPV channels by intracellular spermine

Real-time observation of functional specialization among phosphorylation sites in CFTR

Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development

Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy

ORAI3 is dispensable for store-operated Ca²⁺ entry and immune responses by lymphocytes and macrophages

Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P₂ synthesis

The N2A region of titin has a unique structural configuration

The role of molecular diffusion within dendritic spines in synaptic function

Molecular underpinning of intracellular pH regulation on TMEM16F

The very low number of calcium-induced permeability transition pores in the single mitochondrion

Roles for the SNAP25 linker domain in the fusion pore and a dynamic plasma membrane SNARE “acceptor” complex

Membrane conductances of mouse cone photoreceptors

The central role of the tail in switching off 10S myosin II activity

A primer on resolving the nanoscale structure of the plasma membrane with light and electron microscopy

Evolution of our understanding of cell volume regulation by the pump-leak mechanism

Unraveling the mechanisms of calcium-dependent secretion

Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors

Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion

Visualization of expanding fusion pores in secretory cells

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