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Journal Articles

Na+/Ca2+ exchange in enamel cells is dominated by the K+-dependent NCKX exchanger

Guilherme Henrique Souza Bomfim, Erna Mitaishvili, Paul P.M. Schnetkamp, Rodrigo S. Lacruz
Journal: Journal of General Physiology
J Gen Physiol (2023) 156 (1): e202313372.
https://doi.org/10.1085/jgp.202313372
Published: 10 November 2023
View article titled, Na<sup>+</sup>/Ca<sup>2+</sup> exchange in enamel cells is dominated by the K<sup>+</sup>-dependent NCKX exchanger
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Includes: Supplementary data
Journal Articles

Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects

Gregory W. Busey, Mohan C. Manjegowda, Tao Huang, Wesley H. Iobst, Shardul S. Naphade, Joel A. Kennedy, Catherine A. Doyle, Philip V. Seegren, Kevin R. Lynch, Bimal N. Desai
Journal: Journal of General Physiology
J Gen Physiol (2023) 156 (1): e202313419.
https://doi.org/10.1085/jgp.202313419
Published: 09 November 2023
View article titled, Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects
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Journal Articles

IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels

Scott D. Zawieja, Grace A. Pea, Sarah E. Broyhill, Advaya Patro, Karen H. Bromert, Min Li, Charles E. Norton, Jorge A. Castorena-Gonzalez, Edward J. Hancock, Christopher D. Bertram, Michael J. Davis
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202313358.
https://doi.org/10.1085/jgp.202313358
Published: 18 October 2023
View article titled, IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels
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Includes: Supplementary data
Journal Articles

A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP3R

Edward J. Hancock, Scott D. Zawieja, Charlie Macaskill, Michael J. Davis, Christopher D. Bertram
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202313355.
https://doi.org/10.1085/jgp.202313355
Published: 18 October 2023
View article titled, A dual-clock-driven model of lymphatic muscle cell pacemaking to emulate knock-out of Ano1 or IP<sub>3</sub>R
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Journal Articles

Localized cardiomyocyte lipid accumulation is associated with slowed epicardial conduction in rats

Simon P. Wells, Antonia J.A. Raaijmakers, Claire L. Curl, Christopher O’Shea, Sarah Hayes, Kimberley M. Mellor, Jonathan M. Kalman, Paulus Kirchhof, Davor Pavlovic, Lea M.D. Delbridge, James R. Bell
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202213296.
https://doi.org/10.1085/jgp.202213296
Published: 03 October 2023
View article titled, Localized cardiomyocyte lipid accumulation is associated with slowed epicardial conduction in rats
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Journal Articles

Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol

David R.L. Scriven, Anne Berit Johnsen, Parisa Asghari, Keng C. Chou, Edwin D.W. Moore
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2023) 155 (11): e202213109.
https://doi.org/10.1085/jgp.202213109
Published: 20 September 2023
View article titled, Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol
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Journal Articles

Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models

Ria L. Dinsdale, Cooper E. Roache, Andrea L. Meredith
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313357.
https://doi.org/10.1085/jgp.202313357
Published: 20 September 2023
View article titled, Disease-associated <em>KCNMA1</em> variants decrease circadian clock robustness in channelopathy mouse models
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Includes: Supplementary data
Journal Articles

ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle

Elizabeth J. Akin, Joydeep Aoun, Connor Jimenez, Katie Mayne, Julius Baeck, Michael D. Young, Brennan Sullivan, Kenton M. Sanders, Sean M. Ward, Simon Bulley, Jonathan H. Jaggar, Scott Earley, Iain A. Greenwood, Normand Leblanc
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202213217.
https://doi.org/10.1085/jgp.202213217
Published: 13 September 2023
View article titled, ANO1, Ca<sub>V</sub>1.2, and IP<sub>3</sub>R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle
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Includes: Supplementary data
Journal Articles

Myosin expression and contractile function are altered by replating stem cell–derived cardiomyocytes

Felix Osten, Natalie Weber, Meike Wendland, Tim Holler, Birgit Piep, Simon Kröhn, Jana Teske, Alea K. Bodenschatz, Santoshi Biswanath Devadas, Kaja S. Menge, Shambhabi Chatterjee, Kristin Schwanke, Maike Kosanke, Judith Montag, Thomas Thum, Robert Zweigerdt, Theresia Kraft, Bogdan Iorga, Joachim D. Meissner
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313377.
https://doi.org/10.1085/jgp.202313377
Published: 01 September 2023
View article titled, Myosin expression and contractile function are altered by replating stem cell–derived cardiomyocytes
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Includes: Supplementary data
Journal Articles

The physical basis of osmosis

Gerald S. Manning, Alan R. Kay
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202313332.
https://doi.org/10.1085/jgp.202313332
Published: 25 August 2023
View article titled, The physical basis of osmosis
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Journal Articles

Mitochondrial morphology governs ATP production rate

Guadalupe C. Garcia, Kavya Gupta, Thomas M. Bartol, Terrence J. Sejnowski, Padmini Rangamani
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213263.
https://doi.org/10.1085/jgp.202213263
Published: 24 August 2023
View article titled, Mitochondrial morphology governs ATP production rate
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Journal Articles

Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes

Christine Deisl, Jay H. Chung, Donald W. Hilgemann
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202213329.
https://doi.org/10.1085/jgp.202213329
Published: 09 August 2023
View article titled, Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes
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Includes: Supplementary data
Journal Articles

Urea transport in human red blood cells: Donor variation compared to chloride, glucose, and water transport

Jonas Leifelt, Morten Hanefeld Dziegiel, Jesper Brahm
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202213321.
https://doi.org/10.1085/jgp.202213321
Published: 02 August 2023
View article titled, Urea transport in human red blood cells: Donor variation compared to chloride, glucose, and water transport
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Journal Articles

Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents

In Special Collection:
Neuroscience Collection 2023 , Physiology of Pain Detection and Processing Collection 2023
Sophia Kriegeskorte, Raya Bott, Martin Hampl, Alon Korngreen, Ralf Hausmann, Angelika Lampert
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213312.
https://doi.org/10.1085/jgp.202213312
Published: 02 August 2023
View article titled, Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents
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Includes: Supplementary data
Journal Articles

Mechanistic understanding of KCNQ1 activating polyunsaturated fatty acid analogs

Jessica J. Jowais, Samira Yazdi, Alessia Golluscio, Vanessa Olivier-Meo, Sara I. Liin, H. Peter Larsson
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202313339.
https://doi.org/10.1085/jgp.202313339
Published: 01 August 2023
View article titled, Mechanistic understanding of KCNQ1 activating polyunsaturated fatty acid analogs
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Journal Articles

Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse

Adrien Lesage, Maxime Lorenzini, Sophie Burel, Marine Sarlandie, Floriane Bibault, Cecilia Lindskog, Daniel Maloney, Jonathan R. Silva, R. Reid Townsend, Jeanne M. Nerbonne, Céline Marionneau
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213293.
https://doi.org/10.1085/jgp.202213293
Published: 27 July 2023
View article titled, Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (Na<sub>V</sub>) channels in mouse
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Includes: Supplementary data
Journal Articles

Kv12-encoded K+ channels drive the day–night switch in the repetitive firing rates of SCN neurons

In Special Collection:
Neuroscience Collection 2023
Tracey O. Hermanstyne, Nien-Du Yang, Daniel Granados-Fuentes, Xiaofan Li, Rebecca L. Mellor, Timothy Jegla, Erik D. Herzog, Jeanne M. Nerbonne
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213310.
https://doi.org/10.1085/jgp.202213310
Published: 26 July 2023
View article titled, Kv12-encoded K<sup>+</sup> channels drive the day–night switch in the repetitive firing rates of SCN neurons
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Includes: Supplementary data
Journal Articles

EAAT5 glutamate transporter rapidly binds glutamate with micromolar affinity in mouse rods

Wallace B. Thoreson, Bhavana Chhunchha
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313349.
https://doi.org/10.1085/jgp.202313349
Published: 21 July 2023
View article titled, EAAT5 glutamate transporter rapidly binds glutamate with micromolar affinity in mouse rods
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Journal Articles

Urea and water are transported through different pathways in the red blood cell membrane

Jesper Brahm, Morten Hanefeld Dziegiel, Jonas Leifelt
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (8): e202213322.
https://doi.org/10.1085/jgp.202213322
Published: 30 June 2023
View article titled, Urea and water are transported through different pathways in the red blood cell membrane
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Journal Articles

D-type K+ current rules the function of electrically coupled neurons in a species-specific fashion

In Special Collection:
Neuroscience Collection 2023 , Physiology of Pain Detection and Processing Collection 2023
Antonella Dapino, Federico Davoine, Sebastian Curti
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313353.
https://doi.org/10.1085/jgp.202313353
Published: 28 June 2023
View article titled, D-type K<sup>+</sup> current rules the function of electrically coupled neurons in a species-specific fashion
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Includes: Supplementary data