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Table S1.
Fluidigm gene expression level in BAtTA MPP3
GeneFold change (versus control MPP3)GeneFold change (versus control MPP3)
Axin2 2.89 ± 1.74a Hhip 8.10 ± 5.65b 
Bax 1.17 ± 0.40 Hif1a 1.27 ± 0.27b 
Bbc3 0.74 ± 0.54 Hmga2 0.80 ± 0.21 
Bcl2 1.15 ± 0.25 Hoxa9 0.76 ± 0.22b 
Bcl2l1 0.97 ± 0.24 Id1 2.87 ± 1.04a 
Birc2 0.93 ± 0.13 Ikzf1 0.85 ± 0.12b 
Bmi 0.96 ± 0.17 Il1b 4.34 ± 2.44a 
Cbx7 2.05 ± 1.65 Il6 2.82 ± 0.87a 
Ccl3 2.05 ± 1.65 Il6ra 0.69 ± 0.34 
Ccna2 1.04 ± 0.39 Il7r 3.91 ± 1.95a 
Ccnb1 1.83 ± 0.42a Irf8 0.58 ± 0.30 
Ccnd1 1.75 ± 1.82 Jun 1.65 ± 0.52b 
Ccne1 1.86 ± 1.09b Lef1 0.83 ± 0.68 
Cd34 0.74 ± 0.21b Lrp5 0.95 ± 0.40 
Cd48 0.94 ± 0.39 Mcl1 1.02 ± 0.48 
Cdc20 2.97 ± 1.81b Meis1 0.77 ± 0.16b 
Cdk2 1.05 ± 0.42 Mfng 0.91 ± 0.19 
Cdkn1a 1.08 ± 0.16 Mki67 0.81 ± 0.32 
Cdkn1b 0.81 ± 0.08a Mpl 1.53 ± 1.02 
Cdkn1c 0.66 ± 0.42 Myc 1.04 ± 0.30 
Cebpa 1.18 ± 0.42 Nfe2l2 1.37 ± 0.34b 
Csf1r 1.37 ± 0.72 Nfkbia 1.46 ± 0.51 
Csf2ra 0.78 ± 0.28 Notch1 1.08 ± 0.19 
Csf3r 0.79 ± 0.22 Pai1 10.64 ± 9.71b 
Dnmt1 0.92 ± 0.26 Pax5 1.06 ± 0.33 
Dnmt3a 0.83 ± 0.21 Pdk4 2.53 ± 1.20a 
Ebf1 1.34 ± 0.74 Pmaip1 4.02 ± 2.37b 
Egr1 2.24 ± 1.37b Ppargc1a 0.54 ± 0.18a 
Epor 2.02 ± 1.60 Prkdc 0.74 ± 0.23 
Evi1 0.55 ± 0.20b Ptch1 1.25 ± 0.51 
Ezh1 1.02 ± 0.07 Ptch2 3.03 ± 3.66 
Ezh2 0.79 ± 0.25 Rad51 0.79 ± 0.54 
Flt3 1.07 ± 0.41 Rpa1 0.80 ± 0.34 
Fn1 0.70 ± 0.67 Runx1 0.83 ± 0.11b 
Fos 1.27 ± 0.44 Sfpi1 1.06 ± 0.35 
Foxo3 0.65 ± 0.20b Slamf1 1.41 ± 1.06 
Fzd2 3.30 ± 2.28b Smad7 1.25 ± 0.54 
Gata1 4.32 ± 2.83a Tcf3 0.86 ± 0.07a 
Gata2 2.23 ± 1.26b Tnf 2.14 ± 1.16 
Gfi1 1.50 ± 0.35a Traf1 1.41 ± 0.82 
Gfi1b 1.00 ± 0.57 Vwf 4.05 ± 2.38a 
Gli1 5.17 ± 3.26 Xiap 0.85 ± 0.18 
Hes1 6.46 ± 7.29b Xrcc5 0.99 ± 0.24 
Hes5 1.47 ± 0.75 Xrcc6 1.15 ± 0.29 
Hey1 2.67 ± 1.43b Zfpm1 0.60 ± 0.30b 
Hey2 1.10 ± 0.88   
GeneFold change (versus control MPP3)GeneFold change (versus control MPP3)
Axin2 2.89 ± 1.74a Hhip 8.10 ± 5.65b 
Bax 1.17 ± 0.40 Hif1a 1.27 ± 0.27b 
Bbc3 0.74 ± 0.54 Hmga2 0.80 ± 0.21 
Bcl2 1.15 ± 0.25 Hoxa9 0.76 ± 0.22b 
Bcl2l1 0.97 ± 0.24 Id1 2.87 ± 1.04a 
Birc2 0.93 ± 0.13 Ikzf1 0.85 ± 0.12b 
Bmi 0.96 ± 0.17 Il1b 4.34 ± 2.44a 
Cbx7 2.05 ± 1.65 Il6 2.82 ± 0.87a 
Ccl3 2.05 ± 1.65 Il6ra 0.69 ± 0.34 
Ccna2 1.04 ± 0.39 Il7r 3.91 ± 1.95a 
Ccnb1 1.83 ± 0.42a Irf8 0.58 ± 0.30 
Ccnd1 1.75 ± 1.82 Jun 1.65 ± 0.52b 
Ccne1 1.86 ± 1.09b Lef1 0.83 ± 0.68 
Cd34 0.74 ± 0.21b Lrp5 0.95 ± 0.40 
Cd48 0.94 ± 0.39 Mcl1 1.02 ± 0.48 
Cdc20 2.97 ± 1.81b Meis1 0.77 ± 0.16b 
Cdk2 1.05 ± 0.42 Mfng 0.91 ± 0.19 
Cdkn1a 1.08 ± 0.16 Mki67 0.81 ± 0.32 
Cdkn1b 0.81 ± 0.08a Mpl 1.53 ± 1.02 
Cdkn1c 0.66 ± 0.42 Myc 1.04 ± 0.30 
Cebpa 1.18 ± 0.42 Nfe2l2 1.37 ± 0.34b 
Csf1r 1.37 ± 0.72 Nfkbia 1.46 ± 0.51 
Csf2ra 0.78 ± 0.28 Notch1 1.08 ± 0.19 
Csf3r 0.79 ± 0.22 Pai1 10.64 ± 9.71b 
Dnmt1 0.92 ± 0.26 Pax5 1.06 ± 0.33 
Dnmt3a 0.83 ± 0.21 Pdk4 2.53 ± 1.20a 
Ebf1 1.34 ± 0.74 Pmaip1 4.02 ± 2.37b 
Egr1 2.24 ± 1.37b Ppargc1a 0.54 ± 0.18a 
Epor 2.02 ± 1.60 Prkdc 0.74 ± 0.23 
Evi1 0.55 ± 0.20b Ptch1 1.25 ± 0.51 
Ezh1 1.02 ± 0.07 Ptch2 3.03 ± 3.66 
Ezh2 0.79 ± 0.25 Rad51 0.79 ± 0.54 
Flt3 1.07 ± 0.41 Rpa1 0.80 ± 0.34 
Fn1 0.70 ± 0.67 Runx1 0.83 ± 0.11b 
Fos 1.27 ± 0.44 Sfpi1 1.06 ± 0.35 
Foxo3 0.65 ± 0.20b Slamf1 1.41 ± 1.06 
Fzd2 3.30 ± 2.28b Smad7 1.25 ± 0.54 
Gata1 4.32 ± 2.83a Tcf3 0.86 ± 0.07a 
Gata2 2.23 ± 1.26b Tnf 2.14 ± 1.16 
Gfi1 1.50 ± 0.35a Traf1 1.41 ± 0.82 
Gfi1b 1.00 ± 0.57 Vwf 4.05 ± 2.38a 
Gli1 5.17 ± 3.26 Xiap 0.85 ± 0.18 
Hes1 6.46 ± 7.29b Xrcc5 0.99 ± 0.24 
Hes5 1.47 ± 0.75 Xrcc6 1.15 ± 0.29 
Hey1 2.67 ± 1.43b Zfpm1 0.60 ± 0.30b 
Hey2 1.10 ± 0.88   

Fluidigm analyses in BAtTA MPP3 (n = 6; four pools of 100 cells per mouse, in two independent experiments). Results are expressed as fold change relative to control MPP3 (set to 1) and are mean ± SD; unpaired Student’s t test was used.

a

P < 0.01.

b

P < 0.05.

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