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Table 1

>IL-5 Protein Levels and Its Effects on Peripheral Blood and Femoral Marrow Cellularity

Mouse*HematocritIL-5 Present in the BALSerum IL-5Cell number/mm3 of blood (×10−3)Cell number/femur (×10−6)
TotalLymMonoEosNeuTotalEryLymEosNeu
    ng/total lavage  pg/ml                     
+/+  55.3 (4.6)4  N.D.  N.D.  9.9 (3.0)4  6.1 (3.9)  1.2 (0.5)  0.2 (0.1)  2.5 (1.0)  27.8 (4.9)4  11.0 (2.4)  5.9 (0.9)  0.7 (0.8)  10.1 (5.1) 
NJ.1726  54.3 (4.3)4  269 (37)4  1696 (449)4  41.4 (16.3)4  18.8 (10.6)  2.6 (1.0)  17.3 (8.7)  2.7 (1.5)  30.3 (3.8)4  4.1 (1.6)  3.8 (0.6)  15.2 (1.8)  7.3 (3.9) 
Mouse*HematocritIL-5 Present in the BALSerum IL-5Cell number/mm3 of blood (×10−3)Cell number/femur (×10−6)
TotalLymMonoEosNeuTotalEryLymEosNeu
    ng/total lavage  pg/ml                     
+/+  55.3 (4.6)4  N.D.  N.D.  9.9 (3.0)4  6.1 (3.9)  1.2 (0.5)  0.2 (0.1)  2.5 (1.0)  27.8 (4.9)4  11.0 (2.4)  5.9 (0.9)  0.7 (0.8)  10.1 (5.1) 
NJ.1726  54.3 (4.3)4  269 (37)4  1696 (449)4  41.4 (16.3)4  18.8 (10.6)  2.6 (1.0)  17.3 (8.7)  2.7 (1.5)  30.3 (3.8)4  4.1 (1.6)  3.8 (0.6)  15.2 (1.8)  7.3 (3.9) 

Values appearing as exponents represent the number of animals used to generate the data listed in the table. The numbers in parentheses are the standard deviations associated with the values listed. Differential cell numbers are the calculated averages derived from percent determinations of each cell type for individual animals. All differential percentages were based on ⩾200 cells. N.D., not detected. +/+, C57BL/6J mice. Lym, lymphocyte. Mono, monocyte. Eos, eosinophil. Neu, neutrophil. Ery, erythroblast.  

*

Listed data are derived from mice 7 mo of age.  

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