Table 3

HIV-1 env-specific CTLp Frequencies Over Time

CTLp (95% confidence intervals)
Patientvv*Cord blood2 mo4 mo6 mo7 mo12 mo19 mo
VI-06  vac  34 (23–50)        0.5 (0.03–8)       
  IIIB  13 (7–23)      153 (118–200)       
  vvVI-06-1D  64 (47–87)      197 (151–257)       
VI-05  vac   3 (1–10)           65 (48–89)   
  IIIB   3 (1–9)          219 (169–284)   
  vvVI-05-2M   8 (4–17)          129 (99–168)   
  vvVI-05-6M  ND           55 (40–76)   
VI-08  vac       88 (66–116)   50 (36–70)       19 (12–32) 
  IIIB      240 (184–311)   50 (35–70)      201 (154–262) 
  vvVI-08-20D      165 (127–213)  130 (99–170)       81 (60–108) 
  vvVI-08-6M      202 (156–261)   80 (60–107)      175 (135–229) 
VI-11  vac      8 (4–17)       3 (1–10)   95 (72–125)   
  IIIB     23 (14–36)       4 (1–11)  286 (219–373)   
  vvVI-11-1M    136 (105–177)      42 (29–60)  537 (403–717)   
  vvVI-11-3M    138 (107–180)      70 (52–94)  233 (180–303)   
CTLp (95% confidence intervals)
Patientvv*Cord blood2 mo4 mo6 mo7 mo12 mo19 mo
VI-06  vac  34 (23–50)        0.5 (0.03–8)       
  IIIB  13 (7–23)      153 (118–200)       
  vvVI-06-1D  64 (47–87)      197 (151–257)       
VI-05  vac   3 (1–10)           65 (48–89)   
  IIIB   3 (1–9)          219 (169–284)   
  vvVI-05-2M   8 (4–17)          129 (99–168)   
  vvVI-05-6M  ND           55 (40–76)   
VI-08  vac       88 (66–116)   50 (36–70)       19 (12–32) 
  IIIB      240 (184–311)   50 (35–70)      201 (154–262) 
  vvVI-08-20D      165 (127–213)  130 (99–170)       81 (60–108) 
  vvVI-08-6M      202 (156–261)   80 (60–107)      175 (135–229) 
VI-11  vac      8 (4–17)       3 (1–10)   95 (72–125)   
  IIIB     23 (14–36)       4 (1–11)  286 (219–373)   
  vvVI-11-1M    136 (105–177)      42 (29–60)  537 (403–717)   
  vvVI-11-3M    138 (107–180)      70 (52–94)  233 (180–303)   
*

 vac, vaccinia alone; IIIB, vv expressing IIIB env gp160. See Table 2 for explanation of vaccinia vectors expressing infant isolates.  

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