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Table 1

Differences in the Nucleotide and Amino Acid Sequence Comparing the IL-4Rs of C57BL/6 and BALB/c Mice

cDNA			Peptide
Base^*	C57BL/6	BALB/c	C57BL/6	BALB/c	aa^‡
Extracellular region
78	T	C
100	T	C	Cys	Arg	34
105	A	G
146	C	T	Thr	Ile	49
165	T	C
174	T	C
213	A	G
447	A	T
503	T	C	Met	Thr	168
Cytoplasmic region
861	T	C
926	T	C	Leu	Pro	309
945	A	G
1046	A	G	Asn	Ser	349
1071	A	G	Ile	Met	357
1248	A	G
1340	G	A	Gly	Asp	447
1802	A	G	Asp	Gly	601
2157	C	T

cDNA			Peptide
Base^*	C57BL/6	BALB/c	C57BL/6	BALB/c	aa^‡
Extracellular region
78	T	C
100	T	C	Cys	Arg	34
105	A	G
146	C	T	Thr	Ile	49
165	T	C
174	T	C
213	A	G
447	A	T
503	T	C	Met	Thr	168
Cytoplasmic region
861	T	C
926	T	C	Leu	Pro	309
945	A	G
1046	A	G	Asn	Ser	349
1071	A	G	Ile	Met	357
1248	A	G
1340	G	A	Gly	Asp	447
1802	A	G	Asp	Gly	601
2157	C	T

Numbers indicate the positions of the base exchanges counted from the first nucleotide coding for the mature IL-4R.

‡

Numbers indicate the positions of the amino acid substitutions in the mature IL-4R peptide. The sequence data of the BALB/c IL-4R are available from EMBL/GenBank/DDBJ under accession number AF000304.

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