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Table 1

Phenotypic Characterization of CD8+ T Cell Subsets*

CD45RA+CD27+CD45RA+CD27CD45RACD27+CD45RACD27
Homing receptors         
 CD62L    76 ± 9       28 ± 13        20 ± 7        30 ± 3 
 Integrins         
 CD49d     25 ± 13  87 ± 2        41 ± 15  34 ± 20 
 CD49e     25 ± 14       76 ± 12        56 ± 6    61 ± 12 
 CD29     27 ± 15  93 ± 2        73 ± 6        83 ± 3 
 CD11a   290 ± 60§  716 ± 50  369 ± 100  317 ± 100 
 CD18bright     21 ± 20  87 ± 7  47 ± 17  32 ± 18 
 CD11b         10 ± 7       67 ± 13  9 ± 3        25 ± 3 
         
Activation and costimulatory molecules       
 CD58     18 ± 16  86 ± 8        80 ± 8    88 ± 10 
 CD28     77 ± 12  17 ± 4        83 ± 2        50 ± 7 
 CD57     1.0 ± 0.7       50 ± 13        10 ± 6        14 ± 9 
 CD95   10 ± 1§  29 ± 8        56 ± 2    58 ± 10 
CD45RA+CD27+CD45RA+CD27CD45RACD27+CD45RACD27
Homing receptors         
 CD62L    76 ± 9       28 ± 13        20 ± 7        30 ± 3 
 Integrins         
 CD49d     25 ± 13  87 ± 2        41 ± 15  34 ± 20 
 CD49e     25 ± 14       76 ± 12        56 ± 6    61 ± 12 
 CD29     27 ± 15  93 ± 2        73 ± 6        83 ± 3 
 CD11a   290 ± 60§  716 ± 50  369 ± 100  317 ± 100 
 CD18bright     21 ± 20  87 ± 7  47 ± 17  32 ± 18 
 CD11b         10 ± 7       67 ± 13  9 ± 3        25 ± 3 
         
Activation and costimulatory molecules       
 CD58     18 ± 16  86 ± 8        80 ± 8    88 ± 10 
 CD28     77 ± 12  17 ± 4        83 ± 2        50 ± 7 
 CD57     1.0 ± 0.7       50 ± 13        10 ± 6        14 ± 9 
 CD95   10 ± 1§  29 ± 8        56 ± 2    58 ± 10 
*

 CD8+ cells were >97% CD3+TCR-α/β+CD16 in all subsets.  

 Percentage of positive cells ± SD, n = 5.  

§

 Mean fluorescence intensity ± SD, n = 5.  

 Significant difference (P <0.05) compared to the CD45RA+CD27+ subset (Wilcoxon signed rank test).  

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