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Table 5

Properties of CD8+ T Cell Subsets

NaiveMemoryEffector
Genes expressed       
 CD45RA  +  −  + 
 CD27  +  +  − 
 CD28  +  +  − 
 CD11a  ±  +  ++ 
 CD11b  −  −  ++ 
 CD49d  −  +  ++ 
 CD57  −  −  ++ 
 CD95  −  ++  + 
 Fas ligand  −  ±  ++ 
       
 IL-2  +  ++  − 
 IL-4  −  +  − 
 IFN-γ  −  ++  ++ 
 TNF-α  −  ++  ++ 
       
 Perforin  −  ±  ++ 
 Granzyme B  −  ±  ++ 
       
Functions       
 Cytoxicity  −  ±  ++ 
 B cell differentiation  ↓   ↑   − 
NaiveMemoryEffector
Genes expressed       
 CD45RA  +  −  + 
 CD27  +  +  − 
 CD28  +  +  − 
 CD11a  ±  +  ++ 
 CD11b  −  −  ++ 
 CD49d  −  +  ++ 
 CD57  −  −  ++ 
 CD95  −  ++  + 
 Fas ligand  −  ±  ++ 
       
 IL-2  +  ++  − 
 IL-4  −  +  − 
 IFN-γ  −  ++  ++ 
 TNF-α  −  ++  ++ 
       
 Perforin  −  ±  ++ 
 Granzyme B  −  ±  ++ 
       
Functions       
 Cytoxicity  −  ±  ++ 
 B cell differentiation  ↓   ↑   − 
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