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Table 2

LT α−/− Mice Are Resistant to MOG 35–55 EAE

Group*No. sick/totalDay of onsetMean max clinical scoreDeath totalDisease index
C57BL/6  7/7  13.3  3.5  2/7  386 
LTα+/+  4/4  10.3   2/4  560 
LTα+/−  4/4  14.5  2.6  0/4  234 
LTα−/−  6/9  13.5  0.91§  0/9   61 
Group*No. sick/totalDay of onsetMean max clinical scoreDeath totalDisease index
C57BL/6  7/7  13.3  3.5  2/7  386 
LTα+/+  4/4  10.3   2/4  560 
LTα+/−  4/4  14.5  2.6  0/4  234 
LTα−/−  6/9  13.5  0.91§  0/9   61 
*

 Average of two separate experiments.  

 Disease index calculated on day 30.  

§

P <0.0005 compared to C57BL/6 controls.  

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