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Table 3

WT MOG-specific T Cells Transfer EAE to LT-α−/− Mice

Experiment No. (cells)DonorRecipientNo. sick/totalDay of onsetMean maximum clinical scoreDisease index
1 (MOG T cell line)  B6  Irrad, Pt B6  4/4  9.3  0.88  65 
  B6  Irrad, Pt LT-α−/−  4/4  1.8   1,103 
2 (MOG T cell line)  B6  Irrad B6  1/2   0.5  19 
  B6  Irrad LT-α−/−  5/5  3.6   328 
3 (MOG spleen cells)  B6  B6  1/4  11  0.25  
  B6  LT-α−/−  3/3  5.3   157 
Experiment No. (cells)DonorRecipientNo. sick/totalDay of onsetMean maximum clinical scoreDisease index
1 (MOG T cell line)  B6  Irrad, Pt B6  4/4  9.3  0.88  65 
  B6  Irrad, Pt LT-α−/−  4/4  1.8   1,103 
2 (MOG T cell line)  B6  Irrad B6  1/2   0.5  19 
  B6  Irrad LT-α−/−  5/5  3.6   328 
3 (MOG spleen cells)  B6  B6  1/4  11  0.25  
  B6  LT-α−/−  3/3  5.3   157 
*

 Disease index calculated at 21 d.  

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