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Table 4

LT β−/− Mice Are Susceptible to MOG 35–55 EAE

Group*No. sick/totalDay of onsetMean max clinical scoreDeath totalDisease index
C57BL/6  9/9  10.6   3.3  2/10  515 
LTβ+/−  13/13  8.9   2/13  525 
LTβ−/−  17/17  10.1  1.9§  0/17  312 
Group*No. sick/totalDay of onsetMean max clinical scoreDeath totalDisease index
C57BL/6  9/9  10.6   3.3  2/10  515 
LTβ+/−  13/13  8.9   2/13  525 
LTβ−/−  17/17  10.1  1.9§  0/17  312 
*

 Average of three separate experiments.  

 Disease index calculated at 30 d.  

§

P <0.003 compared to C57BL/6 controls.  

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