Proliferative Responses of Fresh PBMCs from Patients 744 and 024 over Time
| Patient 744 | ||||||||
| Day of bleeding | Day 0 | Day 56 | Day 178 | Day 498 | ||||
| PHA | 44 | 12 | 385 | nt | ||||
| Tetanus toxoid | 40 | nt | 6 | nt | ||||
| Gag p24 peptide pool | 10 | 3.3 | 3.2 | 19 | ||||
| p24-1 | nt | 3.2 | 5.6 | 11 | ||||
| p24-1/16 variant | nt | nt | nt | 1.1 | ||||
| Patient 024 | ||||||||
| Day of bleeding | Day 0 | Day 29 | Day 271 | |||||
| PHA | 239 | 126 | 400 | |||||
| Tetanus toxoid | 98 | nt | ||||||
| Gag p17 peptide pool | 63 | 25 | 18 | |||||
| p17-3 | 24 | 21 | 25 | |||||
| p17-3/1 | nt | nt | 1 | |||||
| p17-3/2 | nt | nt | 1.1 | |||||
| p17-3/3 | nt | nt | 3.7 | |||||
| p17-3/4 | nt | nt | 1.3 |
| Patient 744 | ||||||||
| Day of bleeding | Day 0 | Day 56 | Day 178 | Day 498 | ||||
| PHA | 44 | 12 | 385 | nt | ||||
| Tetanus toxoid | 40 | nt | 6 | nt | ||||
| Gag p24 peptide pool | 10 | 3.3 | 3.2 | 19 | ||||
| p24-1 | nt | 3.2 | 5.6 | 11 | ||||
| p24-1/16 variant | nt | nt | nt | 1.1 | ||||
| Patient 024 | ||||||||
| Day of bleeding | Day 0 | Day 29 | Day 271 | |||||
| PHA | 239 | 126 | 400 | |||||
| Tetanus toxoid | 98 | nt | ||||||
| Gag p17 peptide pool | 63 | 25 | 18 | |||||
| p17-3 | 24 | 21 | 25 | |||||
| p17-3/1 | nt | nt | 1 | |||||
| p17-3/2 | nt | nt | 1.1 | |||||
| p17-3/3 | nt | nt | 3.7 | |||||
| p17-3/4 | nt | nt | 1.3 |
Results are expressed as SI = mean cpm of PBMCs + antigen/mean cpm of PBMCs alone. SI >2.5 was regarded as a positive response. nt, not tested.