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Table 1

Baseline Characteristics of Rhesus Macaques before CD8⁺ T Cell Depletion

			Lymphocyte count		SIVmac239Δnef viral load
Macaque	Immunized	Challenged	CD4⁺ T cells	CD8⁺ T cells	Chiron bDNA plasma	Real-time PCR plasma	Real-time PCR PBMC
			cells/mm³	cells/mm³	RNA copies/ml	RNA copies/ml	copies/10⁶ PBMCs
1496/AT41	SIVmac239Δnef	SIVmac251	581 ± 193	1,317 ± 254	<10⁴	1.1 × 10³	<50
1502/AT44	SIVmac239Δnef	SIVmac251	1,408 ± 218	895 ± 145	<10⁴	2.5 × 10³	<50
1506/AT45	SIVmac239Δnef	SIVmac251	664 ± 141	519 ± 118	<10⁴	1.3 × 10³	<50
1518/AT49	SIVmac239Δnef	–	692 ± 199	738 ± 153	<10⁴	0.2 × 10³	<50
1520/AT50	SIVmac239Δnef	–	989 ± 97	1,709 ± 427	<10⁴	1.8 × 10³	<50
1522/AT51	SIVmac239Δnef	–	695 ± 98	1,288 ± 412	<10⁴	6.1 × 10³	<50

			Lymphocyte count		SIVmac239Δnef viral load
Macaque	Immunized	Challenged	CD4⁺ T cells	CD8⁺ T cells	Chiron bDNA plasma	Real-time PCR plasma	Real-time PCR PBMC
			cells/mm³	cells/mm³	RNA copies/ml	RNA copies/ml	copies/10⁶ PBMCs
1496/AT41	SIVmac239Δnef	SIVmac251	581 ± 193	1,317 ± 254	<10⁴	1.1 × 10³	<50
1502/AT44	SIVmac239Δnef	SIVmac251	1,408 ± 218	895 ± 145	<10⁴	2.5 × 10³	<50
1506/AT45	SIVmac239Δnef	SIVmac251	664 ± 141	519 ± 118	<10⁴	1.3 × 10³	<50
1518/AT49	SIVmac239Δnef	–	692 ± 199	738 ± 153	<10⁴	0.2 × 10³	<50
1520/AT50	SIVmac239Δnef	–	989 ± 97	1,709 ± 427	<10⁴	1.8 × 10³	<50
1522/AT51	SIVmac239Δnef	–	695 ± 98	1,288 ± 412	<10⁴	6.1 × 10³	<50