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Table 1

The Total Number of Splenocytes and Splenic Subpopulations Examined after Treatment with BCMA-Ig

MouseTotal cellsB cellsCD4+ T cellsCD8+ T cellsNeutrophilsMac-1+ cells
BCMA-Ig treated       
B1 58.5 21.5 16.9 7.5 4.6 12.1 
B2 66.0 24.4 19.5 8.3 3.9 12.4 
B3 46.5 11.7 14.9 8.3 3.4 10.0 
B4 36.0 11.0 12.7 6.5 2.2 6.9 
Mean ± SD 51.8 ± 11.4 17.2 ± 5.9 16.0 ± 2.5 7.7 ± 0.7 3.5 ± 0.9 10.4 ± 2.2 
Controls       
A1 73.5 40.4 17.9 6.2 4.1 13.3 
A2 72.8 39.1 16.1 6.6 4.5 13.7 
A3 81.8 42.9 20.4 9.2 3.8 13.2 
A4 43.5 21.6 10.4 4.2 3.2 9.0 
Mean ± SD 67.9 ± 14.5 36.0 ± 8.4 16.2 ± 3.7 6.6 ± 1.8 3.9 ± 0.5 12.3 ± 1.9 
P values P > 0.1 P= 0.02 P > 0.1 P > 0.1 P > 0.1 P > 0.1 
MouseTotal cellsB cellsCD4+ T cellsCD8+ T cellsNeutrophilsMac-1+ cells
BCMA-Ig treated       
B1 58.5 21.5 16.9 7.5 4.6 12.1 
B2 66.0 24.4 19.5 8.3 3.9 12.4 
B3 46.5 11.7 14.9 8.3 3.4 10.0 
B4 36.0 11.0 12.7 6.5 2.2 6.9 
Mean ± SD 51.8 ± 11.4 17.2 ± 5.9 16.0 ± 2.5 7.7 ± 0.7 3.5 ± 0.9 10.4 ± 2.2 
Controls       
A1 73.5 40.4 17.9 6.2 4.1 13.3 
A2 72.8 39.1 16.1 6.6 4.5 13.7 
A3 81.8 42.9 20.4 9.2 3.8 13.2 
A4 43.5 21.6 10.4 4.2 3.2 9.0 
Mean ± SD 67.9 ± 14.5 36.0 ± 8.4 16.2 ± 3.7 6.6 ± 1.8 3.9 ± 0.5 12.3 ± 1.9 
P values P > 0.1 P= 0.02 P > 0.1 P > 0.1 P > 0.1 P > 0.1 

The number of cells (×106) from individual mice in each group is shown. P values were determined by Student's t test.

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