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Table II.

Number of IFN-γ+ CD3+CD4+ or IFN-γ+ CD3+CD8+ cells in the lungs of sensitized and challenged CD8−/− mice that received DMSO-TEFF or GSI-TEFF cells


CD4+IFN-γ+ (×104)
CD8+IFN-γ+ (×104)
CD8-deficient 18.0 ± 1.2 — 
DMSO-TEFF 35.0 ± 5.6 21.6 ± 4.2 
GSI-TEFF 50.7 ± 3.8a 14.3 ± 1.3b 

CD4+IFN-γ+ (×104)
CD8+IFN-γ+ (×104)
CD8-deficient 18.0 ± 1.2 — 
DMSO-TEFF 35.0 ± 5.6 21.6 ± 4.2 
GSI-TEFF 50.7 ± 3.8a 14.3 ± 1.3b 

Mean values ± SEM are given. CD8-deficient, OVA-sensitized and challenged CD8-deficient mice; DMSO-TEFF, DMSO-treated TEFF cell recipient CD8-deficient mice that were OVA sensitized and challenged; GSI-TEFF, GSI-treated TEFF cell recipient CD8-deficient mice that were OVA sensitized and challenged.

a

P < 0.05 compared between GSI-TEFF cells versus CD8-deficient and DMSO-TEFF cells.

b

P < 0.05 compared between GSI-TEFF cells versus DMSO-TEFF cells.

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